PDB: 35140 resultsInfo pagesStatus searchChemie searchBIRD

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6LQZ	Solution structure of Taf14ET-Sth1EBMC Descriptor: Nuclear protein STH1/NPS1, Transcription initiation factor TFIID subunit 14 Authors: Wu, B, Chen, G, Chen, Y. Deposit date: 2020-01-15 Release date: 2020-08-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation. Nat Commun, 11, 2020
6MIN	Crystal structure of Taf14 YEATS domain G82A mutant in complex with histone H3K9cr Descriptor: Histone H3K9cr, Transcription initiation factor TFIID subunit 14 Authors: Klein, B.J, Andrews, F.H, Kutateladze, T.G. Deposit date: 2018-09-19 Release date: 2018-11-14 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9, 2018
6MK0	Integrin AlphaVBeta3 ectodomain bound to antagonist TDI-4161 Descriptor: (2S)-2-[(1,3-benzothiazole-2-carbonyl)amino]-4-{[5-(1,8-naphthyridin-2-yl)pentanoyl]amino}butanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: van Agthoven, J, Arnaout, M.A. Deposit date: 2018-09-24 Release date: 2019-09-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.005 Å) Cite: Novel Pure alphaVbeta3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations Acs Pharmacol Transl Sci, 2, 2019
6MIO	Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr Descriptor: Histone H3K9pr, Transcription initiation factor TFIID subunit 14 Authors: Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G. Deposit date: 2018-09-19 Release date: 2018-11-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9, 2018
8FO2	Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 monomer state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ... Authors: Zhu, H, Sun, J. Deposit date: 2022-12-29 Release date: 2024-01-03 Method: ELECTRON MICROSCOPY (4.13 Å) Cite: Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2. Science, 382, 2023
8FO8	Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 dimer state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ... Authors: Zhu, H, Sun, J. Deposit date: 2022-12-29 Release date: 2024-01-03 Method: ELECTRON MICROSCOPY (3.88 Å) Cite: Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2. Science, 382, 2023
8FO9	Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 tetramer state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ... Authors: Zhu, H, Sun, J. Deposit date: 2022-12-30 Release date: 2024-01-03 Method: ELECTRON MICROSCOPY (3.48 Å) Cite: Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2. Science, 382, 2023
6MIQ	Crystal structure of Taf14 YEATS domain in complex with histone H3K9bu Descriptor: Histone H3K9bu, Transcription initiation factor TFIID subunit 14 Authors: Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G. Deposit date: 2018-09-19 Release date: 2018-11-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9, 2018
4HVW	Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide VSL12 Descriptor: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2012-11-07 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.98 Å) Cite: Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
8FMQ	Complex structure of K210 deletion Troponin complex with alendronate Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-24 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (3.248 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
8FMN	Complex structure of K210 deletion Troponin complex Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-23 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
8FMR	Complex structure of K210 deletion Troponin complex with ibandronate Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-24 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (3.238 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
8FMT	Complex structure of TnnT-R205L Troponin complex Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-24 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
8FMO	Complex structure of K210 deletion Troponin complex with risedronate Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-24 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (2.612 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
4HVV	Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide APP12 Descriptor: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, SYNTHETIC PEPTIDE Acetyl-APPLPPRNRP Authors: Camara-Artigas, A. Deposit date: 2012-11-07 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
8FMS	Complex structure of K210 deletion Troponin complex with neridronate Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-24 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (3.435 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
8FMP	Complex structure of K210 deletion Troponin complex with pamidronate Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-24 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (3.24 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
8FMM	Complex structure of wild type Troponin complex Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... Authors: Wang, P, Ahmed, M, Sadek, H. Deposit date: 2022-12-23 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (3.112 Å) Cite: Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug To Be Published
6MSL	Integrin AlphaVBeta3 ectodomain bound to EETI-II 2.5D Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine Knot Protein 2.5D, ... Authors: van Agthoven, J.F, Arnaout, M.A. Deposit date: 2018-10-16 Release date: 2019-10-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.104 Å) Cite: Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1. Structure, 27, 2019
6MIP	Crystal structure of Taf14 YEATS domain G82A mutant Descriptor: DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14 Authors: Klein, B.J, Andrews, F.H, Kutateladze, T.G. Deposit date: 2018-09-19 Release date: 2018-11-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9, 2018
6MJ2	Human TRPM2 ion channel in a calcium- and ADPR-bound state Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 2 Authors: Wang, L, Fu, T.M, Xia, S, Wu, H. Deposit date: 2018-09-20 Release date: 2018-12-12 Last modified: 2019-01-02 Method: ELECTRON MICROSCOPY (6.36 Å) Cite: Structures and gating mechanism of human TRPM2. Science, 362, 2018
6N88	Cryo-EM structure of the Importin7:Importin beta:Histone H1.0 complex Descriptor: Histone H1.0, Importin subunit beta-1, MGC52556 protein Authors: Bilokapic, S, Ivic, N, Halic, M. Deposit date: 2018-11-28 Release date: 2019-02-27 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Fuzzy Interactions Form and Shape the Histone Transport Complex. Mol. Cell, 73, 2019
6MIX	Human TRPM2 ion channel in apo state Descriptor: Transient receptor potential cation channel subfamily M member 2 Authors: Wang, L, Fu, T.M, Xia, S, Wu, H. Deposit date: 2018-09-20 Release date: 2018-12-12 Last modified: 2019-01-02 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structures and gating mechanism of human TRPM2. Science, 362, 2018
6MIZ	Human TRPM2 ion channel in an ADPR-bound state Descriptor: Transient receptor potential cation channel subfamily M member 2 Authors: Wang, L, Fu, T.M, Xia, S, Wu, H. Deposit date: 2018-09-20 Release date: 2018-12-12 Last modified: 2019-01-02 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Structures and gating mechanism of human TRPM2. Science, 362, 2018
6MSU	Integrin alphaVBeta3 in complex with EETI-II 2.5F Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... Authors: van Agthoven, J.F, Arnaout, M.A. Deposit date: 2018-10-18 Release date: 2019-10-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1. Structure, 27, 2019

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