PDB: 8861 resultsInfo pagesStatus searchChemie searchBIRD

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4MQW	Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31) Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ... Authors: Jiang, X, Liu, H, Chen, X, He, X. Deposit date: 2013-09-16 Release date: 2014-04-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer. J.Biol.Chem., 289, 2014
2CXK	Crystal structure of the TIG domain of human calmodulin-binding transcription activator 1 (CAMTA1) Descriptor: SULFATE ION, calmodulin binding transcription activator 1 Authors: Pioszak, A.A, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-06-30 Release date: 2005-12-30 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of the TIG domain of human calmodulin-binding transcription activator 1 (CAMTA1) To be Published
2UYZ	Non-covalent complex between Ubc9 and SUMO1 Descriptor: SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9 Authors: Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K. Deposit date: 2007-04-21 Release date: 2007-06-12 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation. EMBO J., 26, 2007
1ZFS	Solution structure of S100A1 bound to calcium Descriptor: CALCIUM ION, S-100 protein, alpha chain Authors: Wright, N.T, Varney, K.M, Weber, D.J. Deposit date: 2005-04-20 Release date: 2006-04-11 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The three-dimensional solution structure of Ca(2+)-bound S100A1 as determined by NMR spectroscopy J.Mol.Biol., 353, 2006
4NJ3	Modulating the interaction between CDK2 and Cyclin A with a Quinoline-based inhibitor Descriptor: 6-(3-chlorophenyl)-2-{[(2S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid, Cyclin-dependent kinase 2 Authors: Fischmann, T.O, Hruza, A.W. Deposit date: 2013-11-08 Release date: 2013-11-27 Last modified: 2014-01-08 Method: X-RAY DIFFRACTION (1.848 Å) Cite: Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor. Bioorg.Med.Chem.Lett., 24, 2014
4QA6	Crystal structure of I243N/Y306F HDAC8 in complex with a tetrapeptide substrate Descriptor: 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... Authors: Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. Deposit date: 2014-05-02 Release date: 2014-08-06 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.053 Å) Cite: Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4Q9G	Crystal structure of K12V/C16S/C117V/P134V mutant of human acidic fibroblast growth factor Descriptor: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION Authors: Blaber, M, Xia, X. Deposit date: 2014-05-01 Release date: 2015-03-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.554 Å) Cite: Mutation choice to eliminate buried free cysteines in protein therapeutics. J.Pharm.Sci., 104, 2015
2B52	Human cyclin dependent kinase 2 (CDK2) complexed with DPH-042562 Descriptor: 1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA, Cell division protein kinase 2 Authors: Muckelbauer, J. Deposit date: 2005-09-27 Release date: 2005-10-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. Part 4: Heterocycles at C3 Bioorg.Med.Chem.Lett., 14, 2004
4QA2	Crystal structure of I243N HDAC8 in complex with SAHA Descriptor: GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... Authors: Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. Deposit date: 2014-05-02 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.377 Å) Cite: Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QBC	Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium formate buffer Descriptor: FORMIC ACID, Fibroblast growth factor 1, SULFATE ION Authors: Blaber, M, Xia, X. Deposit date: 2014-05-07 Release date: 2015-03-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.519 Å) Cite: Mutation choice to eliminate buried free cysteines in protein therapeutics. J.Pharm.Sci., 104, 2015
4QBV	Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium citrate buffer Descriptor: CITRATE ANION, Fibroblast growth factor 1 Authors: Blaber, M, Xia, X. Deposit date: 2014-05-08 Release date: 2015-03-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.497 Å) Cite: Mutation choice to eliminate buried free cysteines in protein therapeutics. J.Pharm.Sci., 104, 2015
1JEQ	Crystal Structure of the Ku Heterodimer Descriptor: KU70, KU80 Authors: Walker, J.R, Corpina, R.A, Goldberg, J. Deposit date: 2001-06-18 Release date: 2001-08-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature, 412, 2001
2C6M	Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor Descriptor: 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 Authors: Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. Deposit date: 2005-11-10 Release date: 2005-12-07 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Triazolo[1,5-A]Pyrimidines as Novel Cdk2 Inhibitors: Protein Structure-Guided Design and Sar. Bioorg.Med.Chem.Lett., 16, 2006
1FRO	HUMAN GLYOXALASE I WITH BENZYL-GLUTATHIONE INHIBITOR Descriptor: LACTOYLGLUTATHIONE LYASE, S-BENZYL-GLUTATHIONE, ZINC ION Authors: Cameron, A.D, Jones, T.A. Deposit date: 1997-02-25 Release date: 1997-06-16 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping. EMBO J., 16, 1997
5ZMP	The structure of a lysine deacylase Descriptor: ZINC ION, lysine deacylase Authors: Ge, F. Deposit date: 2018-04-05 Release date: 2019-02-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.19 Å) Cite: The structure of a lysine deacylase To Be Published
2DAO	Solution structure of ETS domain Transcriptional factor ETV6 protein Descriptor: Transcription factor ETV6 Authors: Niraula, T.N, Sasagawa, A, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-12-14 Release date: 2006-12-12 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of ETS domain Transcriptional factor ETV6 protein To be Published
1FXF	CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + MJ33 INHIBITOR + PHOSPHATE IONS) Descriptor: 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHATE ION, ... Authors: Pan, Y.H, Epstein, T.M, Jain, M.K, Bahnson, B.J. Deposit date: 2000-09-25 Release date: 2001-09-25 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Five coplanar anion binding sites on one face of phospholipase A2: relationship to interface binding. Biochemistry, 40, 2001
2DMU	Solution structure of the homeobox domain of Homeobox protein goosecoid Descriptor: Homeobox protein goosecoid Authors: Ohnishi, S, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-24 Release date: 2006-10-24 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the homeobox domain of Homeobox protein goosecoid To be Published
4EK5	Crystal structure of the cdk2 in complex with aminopyrazole inhibitor Descriptor: Cyclin-dependent kinase 2, N-(5-cyclopropyl-1H-pyrazol-3-yl)benzene-1,4-dicarboxamide Authors: Kang, Y.N, Stuckey, J.A. Deposit date: 2012-04-09 Release date: 2013-05-01 Last modified: 2013-05-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of the cdk2 in complex with aminopyrazole inhibitor To be Published
4ERW	CDK2 in complex with staurosporine Descriptor: 1,2-ETHANEDIOL, Cyclin-dependent kinase 2, STAUROSPORINE Authors: Alam, R, Martin, M.P, Zhu, J.-Y, Schonbrunn, E. Deposit date: 2012-04-20 Release date: 2012-08-22 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2 Å) Cite: A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13, 2012
2DMT	Solution structure of the homeobox domain of Homeobox protein BarH-like 1 Descriptor: Homeobox protein BarH-like 1 Authors: Ohnishi, S, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-24 Release date: 2006-10-24 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the homeobox domain of Homeobox protein BarH-like 1 To be Published
2DVW	Structure of the Oncoprotein Gankyrin in Complex with S6 ATPase of the 26S Proteasome Descriptor: 26S protease regulatory subunit 6B, 26S proteasome non-ATPase regulatory subunit 10 Authors: Yokoyama, S, Padmanabhan, B, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-08-01 Release date: 2007-03-13 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the Oncoprotein Gankyrin in Complex with S6 ATPase of the 26S Proteasome Structure, 15, 2007
2DJN	The solution structure of the homeobox domain of human Homeobox protein DLX-5 Descriptor: Homeobox protein DLX-5 Authors: Sasagawa, A, Ohnishi, S, Tochio, N, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-05 Release date: 2006-10-05 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: The solution structure of the homeobox domain of human Homeobox protein DLX-5 To be Published
2DO3	Solution structure of the third KOW motif of transcription elongation factor SPT5 Descriptor: Transcription elongation factor SPT5 Authors: Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-27 Release date: 2006-10-27 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the third KOW motif of transcription elongation factor SPT5 To be Published
4EK8	Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor Descriptor: 4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)pyrimidin-2-amine, Cyclin-dependent kinase 2 Authors: Kang, Y.N, Stuckey, J.A. Deposit date: 2012-04-09 Release date: 2013-05-01 Last modified: 2013-05-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor To be Published

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