PDB: 1288 resultsInfo pagesStatus searchChemie searchBIRD

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5MRE	Structure of the yeast mitochondrial ribosome - Class B Descriptor: 15S ribosomal RNA, 21S ribosomal RNA, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Desai, N, Brown, A, Amunts, A, Ramakrishnan, V. Deposit date: 2016-12-22 Release date: 2017-02-15 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: The structure of the yeast mitochondrial ribosome. Science, 355, 2017
1Y8F	Solution structure of the munc13-1 C1-domain Descriptor: Unc-13 homolog A, ZINC ION Authors: Shen, N, Guryev, O, Rizo, J. Deposit date: 2004-12-12 Release date: 2005-04-12 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1. Biochemistry, 44, 2005
7M4U	A. baumannii Ribosome-Eravacycline complex: 30S Descriptor: 16s Ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Morgan, C.E, Yu, E.W. Deposit date: 2021-03-22 Release date: 2021-05-19 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii. Mbio, 12, 2021
3HPI	Crystal structure of maltose-binding protein mutant with bound sucrose Descriptor: ACETATE ION, Maltose-binding periplasmic protein, ZINC ION, ... Authors: Gould, A.D, Shilton, B.H. Deposit date: 2009-06-04 Release date: 2010-02-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Studies of the maltose transport system reveal a mechanism for coupling ATP hydrolysis to substrate translocation without direct recognition of substrate. J.Biol.Chem., 285, 2010
7M4X	A. baumannii Ribosome-Eravacycline complex: P-site tRNA 70S Descriptor: 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ... Authors: Morgan, C.E, Yu, E.W. Deposit date: 2021-03-22 Release date: 2021-05-19 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.66 Å) Cite: Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii. Mbio, 12, 2021
6YT9	Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit body Descriptor: 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... Authors: Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. Deposit date: 2020-04-24 Release date: 2020-09-16 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
6ZIS	Crystal structure of a CGRP receptor ectodomain heterodimer with bound high affinity inhibitor Descriptor: Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, N-{(1S)-5-amino-1-[(4-pyridin-4-ylpiperazin-1-yl)carbonyl]pentyl}-3,5-dibromo-Nalpha-{[4-(2-oxo-1,4-dihydroquinazolin-3 (2H)-yl)piperidin-1-yl]carbonyl}-D-tyrosinamide, TETRAETHYLENE GLYCOL, ... Authors: Southall, S.M. Deposit date: 2020-06-26 Release date: 2020-07-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Structure-Based Drug Discovery ofN-((R)-3-(7-Methyl-1H-indazol-5-yl)-1-oxo-1-(((S)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine. J.Med.Chem., 63, 2020
6ZLD	Crystal Structure of UDP-Glucuronic acid 4-epimerase from Bacillus cereus in complex with UDP-Glucuronic acid and NAD Descriptor: Epimerase domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID Authors: Iacovino, L.G, Savino, S, Mattevi, A. Deposit date: 2020-06-30 Release date: 2020-07-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction. J.Biol.Chem., 295, 2020
1Y8P	Crystal structure of the PDK3-L2 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, ... Authors: Kato, M, Chuang, J.L, Wynn, R.M, Chuang, D.T. Deposit date: 2004-12-13 Release date: 2005-05-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.63 Å) Cite: Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex. Embo J., 24, 2005
6ZLL	Crystal Structure of UDP-Glucuronic acid 4-epimerase from Bacillus cereus in complex with UDP-Galacturonic acid and NAD Descriptor: (2S,3R,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic acid, Epimerase domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Iacovino, L.G, Savino, S, Mattevi, A. Deposit date: 2020-06-30 Release date: 2020-07-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction. J.Biol.Chem., 295, 2020
6QYK	Structure of MBP-Mcl-1 in complex with compound 7a Descriptor: (2~{R})-2-[6-ethyl-5-(1~{H}-indol-5-yl)thieno[2,3-d]pyrimidin-4-yl]oxypropanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Authors: Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. Deposit date: 2019-03-09 Release date: 2019-08-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
5MM3	Unstructured MamC magnetite-binding protein located between two helices. Descriptor: Sugar ABC transporter substrate-binding protein,Magnetosome protein MamC,Sugar ABC transporter substrate-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Authors: Nudelman, H, Zarivach, R. Deposit date: 2016-12-08 Release date: 2017-10-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The importance of the helical structure of a MamC-derived magnetite-interacting peptide for its function in magnetite formation. Acta Crystallogr D Struct Biol, 74, 2018
6SMV	Structure of HPV49 E6 protein in complex with MAML1 LxxLL motif Descriptor: DI(HYDROXYETHYL)ETHER, Maltose/maltodextrin-binding periplasmic protein,Protein E6,Mastermind-like protein 1, ZINC ION, ... Authors: Suarez, I.P, Cousido-Siah, A, Bonhoure, A, Kostmann, C, Mitschler, A, Podjarny, A, Trave, G. Deposit date: 2019-08-22 Release date: 2019-09-04 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Cellular target recognition by HPV18 and HPV49 oncoproteins To be published
6NDJ	Crystal structure of human NLRP6 PYD domain with MBP fusion Descriptor: Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera Authors: Shen, C, Fu, T.M, Wu, H. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Molecular mechanism for NLRP6 inflammasome assembly and activation. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6QYN	Structure of MBP-Mcl-1 in complex with compound 10d Descriptor: (2~{R})-2-[5-(3-chloranyl-2-methyl-4-oxidanyl-phenyl)-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Authors: Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. Deposit date: 2019-03-09 Release date: 2019-08-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
1AKO	EXONUCLEASE III FROM ESCHERICHIA COLI Descriptor: EXONUCLEASE III Authors: Mol, C.D, Kuo, C.-F, Thayer, M.M, Cunningham, R.P, Tainer, J.A. Deposit date: 1997-05-26 Release date: 1997-08-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure and function of the multifunctional DNA-repair enzyme exonuclease III. Nature, 374, 1995
6QYO	Structure of MBP-Mcl-1 in complex with compound 18a Descriptor: (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Authors: Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. Deposit date: 2019-03-09 Release date: 2019-08-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
7NZM	Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... Authors: Yan, Y, Hardwick, S, Ron, D. Deposit date: 2021-03-24 Release date: 2021-09-29 Last modified: 2021-10-20 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
1ZKB	Zinc-free Engineered maltose binding protein Descriptor: Maltose-binding periplasmic protein Authors: Telmer, P.G, Shilton, B.H. Deposit date: 2005-05-02 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural studies of an engineered zinc biosensor reveal an unanticipated mode of zinc binding. J.Mol.Biol., 354, 2005
6SIV	Structure of HPV16 E6 oncoprotein in complex with mutant IRF3 LxxLL motif Descriptor: Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3, Protein E6, ZINC ION, ... Authors: Suarez, I.P, Cousido-Siah, A, Bonhoure, A, Mitschler, A, Podjarny, A, Trave, G. Deposit date: 2019-08-12 Release date: 2019-08-21 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.752 Å) Cite: Deciphering the molecular and structural interaction between IRF3 and HPV16 E6 To be published
1ZN9	Human Adenine Phosphoribosyltransferase in Apo and AMP Complexed Forms Descriptor: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase Authors: Iulek, J, Silva, M, Tomich, C.H.T.P, Thiemann, O.H. Deposit date: 2005-05-11 Release date: 2006-04-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism J.Biomol.Struct.Dyn., 25, 2008
1ANW	THE EFFECT OF METAL BINDING ON THE STRUCTURE OF ANNEXIN V AND IMPLICATIONS FOR MEMBRANE BINDING Descriptor: ANNEXIN V, CALCIUM ION Authors: Lewit-Bentley, A, Morera, S, Huber, R, Bodo, G. Deposit date: 1993-10-26 Release date: 1994-12-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The effect of metal binding on the structure of annexin V and implications for membrane binding. Eur.J.Biochem., 210, 1992
6O7H	Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system Descriptor: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ... Authors: Jia, N, Patel, D.J. Deposit date: 2019-03-07 Release date: 2019-07-31 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75, 2019
1Y8O	Crystal structure of the PDK3-L2 complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, ... Authors: Kato, M, Chuang, J.L, Wynn, R.M, Chuang, D.T. Deposit date: 2004-12-13 Release date: 2005-05-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex. Embo J., 24, 2005
6OFW	Dihydropteroate synthase from Xanthomonas albilineans in complex with 7,8-dihydropteroate Descriptor: 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoic acid, Dihydropteroate synthase, SULFATE ION Authors: Oliveira, A.A, Guido, R.V.C, Maluf, F.V, Bueno, R.V, Lima, G.M.A. Deposit date: 2019-04-01 Release date: 2020-04-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Dihydropteroate synthase from Xanthomonas albilineans in complex with 7,8-dihydropteroate To Be Published

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