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2MQF
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BU of 2mqf by Molmil
NMR structure of spider toxin-TRTX-Hhn2b
Descriptor: Mu-theraphotoxin-Hhn2b
Authors:Klint, J.K, Chin, Y.K.Y, Mobli, M.
Deposit date:2014-06-19
Release date:2015-07-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7
Mol.Pharmacol., 88, 2015
2MXM
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BU of 2mxm by Molmil
NMR solution structure of TRTX-Tp1a from the tarantula Thrixopelma pruriens
Descriptor: entity
Authors:Rosengren, K.
Deposit date:2015-01-08
Release date:2015-06-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Identification and Characterization of ProTx-III [ mu-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.
Mol.Pharmacol., 88, 2015
2N6O
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BU of 2n6o by Molmil
Structure of spider-venom peptide Hm1a
Descriptor: Kappa-theraphotoxin-Hm1a
Authors:Undheim, E.A.B, King, G.F, Mobli, M.
Deposit date:2015-08-27
Release date:2016-09-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of spider-venom peptide Hm1a
To be Published
6W6O
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BU of 6w6o by Molmil
NaChBac-Nav1.7VSDII chimera and HWTX-IV complex
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Huwentoxin-IV, NaChBac-Nav1.7VSDII chimera
Authors:Yan, N, Gao, S.
Deposit date:2020-03-17
Release date:2020-06-24
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc.
Proc.Natl.Acad.Sci.USA, 117, 2020
7K48
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BU of 7k48 by Molmil
Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a
Authors:Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A.
Deposit date:2020-09-15
Release date:2020-12-02
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin.
Mol.Cell, 81, 2021
3J5Q
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BU of 3j5q by Molmil
Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy
Descriptor: Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M, Cao, E, Julius, D, Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
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數據於2024-06-19公開中

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