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5YKE	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A) Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11 Authors: Chen, L, Wu, J.X. Deposit date: 2017-10-14 Release date: 2018-04-18 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.11 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWC	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW9	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A) Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (5 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWB	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-30 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW8	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A) Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWA	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A) Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
7U2X	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-25 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7UAA	CryoEM structure of the pancreatic ATP-sensitive potassium channel in the ATP-bound state with Kir6.2-CTD in the up conformation Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-03-11 Release date: 2022-08-31 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7TYS	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the up conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-14 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U6Y	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of glibenclamide and ATP with Kir6.2-CTD in the down conformation Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-03-06 Release date: 2022-08-31 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (7.4 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U24	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-23 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7TYT	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the down conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-14 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1E	CryoEM structure of the pancreatic ATP-sensitive potassium channel bound to ATP with Kir6.2-CTD in the down conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-21 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (4.52 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1S	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-22 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1Q	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-21 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U7M	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-03-07 Release date: 2022-08-31 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7UQR	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the apo form with Kir6.2-CTD in the down conformation Descriptor: ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-04-20 Release date: 2022-08-31 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (4.55 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022

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