PDB: 195 resultsInfo pagesStatus searchChemie searchBIRD

---

5MLW	Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide Descriptor: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION Authors: Ariza, A. Deposit date: 2016-12-07 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
5MLO	Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide Descriptor: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide Authors: Ariza, A. Deposit date: 2016-12-07 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
5MAV	Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide. Descriptor: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen Authors: Grishkovskaya, I, Djinovic-Carugo, K, Slade, D. Deposit date: 2016-11-06 Release date: 2017-08-02 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.575 Å) Cite: A novel non-canonical PIP-box mediates PARG interaction with PCNA. Nucleic Acids Res., 45, 2017
4YHR	Crystal Structure of Yeast Proliferating Cell Nuclear Antigen Descriptor: Proliferating cell nuclear antigen Authors: Litman, J.M, Nguyen, V.Q, Kondratick, C.M, Powers, K.T, Schnieders, M.J, Washington, M.T. Deposit date: 2015-02-27 Release date: 2015-03-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.9502 Å) Cite: Dead-End Elimination with a Polarizable Force Field Repacks PCNA Models from Low-Resolution X-ray Diffraction into Atomic Resolution Structures To be published
5MOM	Crystal Structure of PCNA encoding the hypomorphic mutation S228I Descriptor: Proliferating cell nuclear antigen Authors: Biasutto, A.J, Mancini, E.J, Green, C.M, Wilson, R.H.C. Deposit date: 2016-12-14 Release date: 2017-01-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.27 Å) Cite: PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst.), 50, 2017
4ZTD	Crystal Structure of Human PCNA in complex with a TRAIP peptide Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen Authors: Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. Deposit date: 2015-05-14 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.199 Å) Cite: TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J.Cell Biol., 212, 2016
5A6D	Proliferating Cell Nuclear Antigen, PCNA, from Thermococcus gammatolerans Descriptor: DNA POLYMERASE SLIDING CLAMP Authors: Venancio-Landeros, A, Cardona-Felix, C.S, Rudino-Pinera, E. Deposit date: 2015-06-25 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans. Biochem Biophys Rep, 8, 2016
5AUJ	Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative Descriptor: DNA polymerase sliding clamp Authors: Watanabe, Y, Oyama, T. Deposit date: 2015-04-21 Release date: 2016-04-27 Last modified: 2020-02-19 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative To Be Published
6EHT	Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme Descriptor: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ... Authors: De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. Deposit date: 2017-09-15 Release date: 2018-08-08 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: p15PAF binding to PCNA modulates the DNA sliding surface. Nucleic Acids Res., 46, 2018
3LX2	Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582 Descriptor: DNA polymerase sliding clamp 2, SULFATE ION Authors: Ladner, J.E, Kelman, Z, Pan, M. Deposit date: 2010-02-24 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
6FCM	Crystal structure of human PCNA Descriptor: Proliferating cell nuclear antigen Authors: Housset, D, Frachet, P. Deposit date: 2017-12-20 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
7QNZ	human Lig1-DNA-PCNA complex reconstituted in absence of ATP Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Oligo13P, ... Authors: Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. Deposit date: 2021-12-23 Release date: 2023-01-11 Method: ELECTRON MICROSCOPY (4.58 Å) Cite: Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing. Nat Commun, 13, 2022
7QO1	complex of DNA ligase I and FEN1 on PCNA and DNA Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ... Authors: Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. Deposit date: 2021-12-23 Release date: 2023-01-11 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing. Nat Commun, 13, 2022
6FCN	Crystal structure of human PCNA soaked with p47phox(106-127) peptide Descriptor: Proliferating cell nuclear antigen Authors: Housset, D, Frachet, P. Deposit date: 2017-12-20 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.22 Å) Cite: Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
7RPX	Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA Descriptor: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-04 Release date: 2021-11-17 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPO	Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-03 Release date: 2021-11-17 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPW	Archaeal DNA ligase and heterotrimeric PCNA in complex with adenylated DNA Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-04 Release date: 2021-11-17 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.38 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
6GWS	Crystal structure of human PCNA in complex with three p15 peptides Descriptor: PCNA-associated factor, Proliferating cell nuclear antigen Authors: De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A. Deposit date: 2018-06-25 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.9 Å) Cite: p15PAF binding to PCNA modulates the DNA sliding surface. Nucleic Acids Res., 46, 2018
6GIS	Structural basis of human clamp sliding on DNA Descriptor: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen Authors: De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. Deposit date: 2018-05-15 Release date: 2018-05-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Structural basis of human PCNA sliding on DNA. Nat Commun, 8, 2017
3WGW	Structure of PCNA bound to a small molecule inhibitor Descriptor: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION Authors: Hashimoto, H. Deposit date: 2013-08-12 Release date: 2014-02-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
8P9O	PCNA from Chaetomium thermophilum in complex with PolD3 peptide Descriptor: Proliferating cell nuclear antigen, Synthetic peptide corresponding to amino acids 437 to 451 of PolD3 from Chaetomium thermophilum Authors: Alphey, M.S, Wolford, C.B, MacNeill, S.A. Deposit date: 2023-06-06 Release date: 2023-12-13 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA. Front Mol Biosci, 10, 2023
8Q7I	PCNA from Chaetomium thermophilum in complex with Fen1 peptide Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION Authors: Alphey, M.S, Wolford, C.B, MacNeill, S.A. Deposit date: 2023-08-16 Release date: 2023-12-13 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA. Front Mol Biosci, 10, 2023
3LX1	Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535 Descriptor: DNA polymerase sliding clamp 1, SULFATE ION Authors: Ladner, J.E, Kelman, Z, Pan, M. Deposit date: 2010-02-24 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
3P91	Crystal structure of Proliferating Cellular Nuclear Antigen from Entamoeba histolytica Descriptor: Proliferating cell nuclear antigen Authors: Lara-Gonzalez, S, Cardona-Felix, C.S, Brieba, L.G. Deposit date: 2010-10-15 Release date: 2011-06-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure and biochemical characterization of proliferating cellular nuclear antigen from a parasitic protozoon. Acta Crystallogr.,Sect.D, 67, 2011
3VKX	Structure of PCNA Descriptor: 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... Authors: Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. Deposit date: 2011-11-26 Release date: 2012-03-14 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012

<12345678>