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2XRD
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BU of 2xrd by Molmil
Structure of the N-terminal four domains of the complement regulator Rat Crry
Descriptor: COMPLEMENT REGULATORY PROTEIN CRRY
Authors:Leath, K.J, Roversi, P, Johnson, S, Morgan, B.P, Lea, S.M.
Deposit date:2010-09-14
Release date:2011-06-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structures of the Rat Complement Regulator Crry.
Acta Crystallogr.,Sect.F, 67, 2011
2XRB
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BU of 2xrb by Molmil
Structure of the N-terminal four domains of the complement regulator Rat Crry
Descriptor: 1,2-ETHANEDIOL, COMPLEMENT REGULATORY PROTEIN CRRY, SULFATE ION
Authors:Leath, K.J, Roversi, P, Johnson, S, Morgan, B.P, Lea, S.M.
Deposit date:2010-09-13
Release date:2011-06-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the Rat Complement Regulator Crry.
Acta Crystallogr.,Sect.F, 67, 2011
2YRA
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BU of 2yra by Molmil
Solution structure of the zinc finger domains (1-87) from human F-box only protein
Descriptor: Seizure 6-like protein isoform 3
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-02
Release date:2007-10-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the zinc finger domains (1-87) from human F-box only protein
To be Published
2YBY
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BU of 2yby by Molmil
Structure of domains 6 and 7 of the mouse complement regulator Factor H
Descriptor: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H
Authors:Everett, R.J, Caesar, J.J.E, Johnson, S.J, Tang, C.M, Lea, S.M.
Deposit date:2011-03-30
Release date:2012-04-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
8ACF
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BU of 8acf by Molmil
Structure of the argX-117 in complex with a complement C2 fragment at low pH
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2022-07-05
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
8ACI
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BU of 8aci by Molmil
Structure of ARG-117 Fab in complex with a fragment of complement C2, neutral pH
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ARGX-117 Fab heavy chain, ARGX-117 Fab light chain, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2022-07-05
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
7ZJM
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BU of 7zjm by Molmil
Crystal structure of a complex between CspZ from Borrelia burgdorferi strain B408 and human FH SCR domains 6-7
Descriptor: Complement factor H, CspZ, DI(HYDROXYETHYL)ETHER, ...
Authors:Brangulis, K, Marcinkiewicz, A, Hart, T.M, Dupuis, A.P, Zamba Campero, M, Nowak, T.A, Stout, J.L, Akopjana, I, Kazaks, A, Bogans, J, Ciota, A.T, Kraiczy, P, Kolokotronis, S.O, Lin, Y.-P.
Deposit date:2022-04-11
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural evolution of an immune evasion determinant shapes pathogen host tropism.
Proc.Natl.Acad.Sci.USA, 120, 2023
1NWV
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BU of 1nwv by Molmil
SOLUTION STRUCTURE OF A FUNCTIONALLY ACTIVE COMPONENT OF DECAY ACCELERATING FACTOR
Descriptor: Complement decay-accelerating factor
Authors:Uhrinova, S, Lin, F, Ball, G, Bromek, K, Uhrin, D, Medof, M.E, Barlow, P.N.
Deposit date:2003-02-07
Release date:2003-04-22
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a functionally active fragment of decay-accelerating factor
Proc.Natl.Acad.Sci.USA, 100, 2003
1OK1
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BU of 1ok1 by Molmil
Decay accelerating factor (cd55) : the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK9
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BU of 1ok9 by Molmil
Decay accelerating factor (CD55): The structure of an intact human complement regulator.
Descriptor: ACETATE ION, CHLORIDE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-21
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJW
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BU of 1ojw by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, SULFATE ION
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK3
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BU of 1ok3 by Molmil
Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJV
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BU of 1ojv by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJY
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BU of 1ojy by Molmil
Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK2
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BU of 1ok2 by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1PPQ
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BU of 1ppq by Molmil
NMR structure of 16th module of Immune Adherence Receptor, Cr1 (Cd35)
Descriptor: Complement receptor type 1
Authors:O'Leary, J.M, Bromek, K, Black, G.M, Uhrinova, S, Schmitz, C, Krych, M, Atkinson, J.P, Uhrin, D, Barlow, P.N.
Deposit date:2003-06-17
Release date:2004-05-04
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.
Protein Sci., 13, 2004
1SS2
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BU of 1ss2 by Molmil
Solution structure of the second complement control protein (CCP) module of the GABA(B)R1a receptor, Pro-119 cis conformer
Descriptor: Gamma-aminobutyric acid type B receptor, subunit 1
Authors:Blein, S, Uhrin, D, Smith, B.O, White, J.H, Barlow, P.N.
Deposit date:2004-03-23
Release date:2004-10-12
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded.
J.Biol.Chem., 279, 2004
1SRZ
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BU of 1srz by Molmil
Solution structure of the second complement control protein (CCP) module of the GABA(B)R1a receptor, Pro-119 trans conformer
Descriptor: Gamma-aminobutyric acid type B receptor, subunit 1
Authors:Blein, S, Uhrin, D, Smith, B.O, White, J.H, Barlow, P.N.
Deposit date:2004-03-23
Release date:2004-10-12
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural Analysis of the Complement Control Protein (CCP) Modules of GABAB Receptor 1a: ONLY ONE OF THE TWO CCP MODULES IS COMPACTLY FOLDED
J.Biol.Chem., 279, 2004
1E5G
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BU of 1e5g by Molmil
Solution structure of central CP module pair of a pox virus complement inhibitor
Descriptor: COMPLEMENT CONTROL PROTEIN C3
Authors:Henderson, C.E, Bromek, K, Mullin, N.P, Smith, B.O, Uhrin, D, Barlow, P.N.
Deposit date:2000-07-25
Release date:2000-08-31
Last modified:2013-07-03
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of the Central Ccp Module Pair of a Poxvirus Complement Control Protein
J.Mol.Biol., 307, 2001
1GKG
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BU of 1gkg by Molmil
Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)
Descriptor: COMPLEMENT RECEPTOR TYPE 1
Authors:Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N.
Deposit date:2001-08-14
Release date:2002-04-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
Cell(Cambridge,Mass.), 108, 2002
2Q7Z
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BU of 2q7z by Molmil
Solution Structure of the 30 SCR domains of human Complement Receptor 1
Descriptor: Complement receptor type 1
Authors:Furtado, P.B, Huang, C.Y, Ihyembe, D, Hammond, R.A, Marsh, H.C, Perkins, S.J.
Deposit date:2007-06-08
Release date:2007-10-16
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands
J.Mol.Biol., 375, 2008
1GKN
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BU of 1gkn by Molmil
Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)
Descriptor: COMPLEMENT RECEPTOR TYPE 1
Authors:Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N.
Deposit date:2001-08-16
Release date:2002-04-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
Cell(Cambridge,Mass.), 108, 2002
2QFG
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BU of 2qfg by Molmil
Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H.
Descriptor: Complement factor H
Authors:Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J.
Deposit date:2007-06-27
Release date:2007-09-25
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
2QZH
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BU of 2qzh by Molmil
SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF
Descriptor: Complement decay-accelerating factor
Authors:Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G.
Deposit date:2007-08-16
Release date:2007-10-30
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (14 Å)
Cite:Interaction of decay-accelerating factor with coxsackievirus b3.
J.Virol., 81, 2007
1H04
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BU of 1h04 by Molmil
Human CD55 domains 3 & 4
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR, NICKEL (II) ION
Authors:Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M.
Deposit date:2002-06-11
Release date:2003-03-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003

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數據於2024-05-29公開中

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