PDB: 256 resultsInfo pagesStatus searchChemie searchBIRD

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3PZF	1.75A resolution structure of Serpin-2 from Anopheles gambiae Descriptor: Serpin 2 Authors: Lovell, S, Battaile, K.P, An, C, Michel, K. Deposit date: 2010-12-14 Release date: 2011-02-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoes. Proteins, 79, 2011
3Q03	Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation. Descriptor: CHLORIDE ION, Plasminogen activator inhibitor 1, ZINC ION Authors: Jensen, J.K, Morth, J.P. Deposit date: 2010-12-15 Release date: 2011-06-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6401 Å) Cite: Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability. J.Biol.Chem., 286, 2011
4G8O	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 Descriptor: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ... Authors: Stuckey, J.A, Lawrence, D.A, Li, S.-H. Deposit date: 2012-07-23 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
4GA7	Crystal structure of human serpinB1 mutant Descriptor: Leukocyte elastase inhibitor Authors: Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. Deposit date: 2012-07-25 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
2ZNH	Crystal Structure of a Domain-Swapped Serpin Dimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... Authors: Yamasaki, M, Huntington, J.A. Deposit date: 2008-04-25 Release date: 2008-10-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization Nature, 455, 2008
4IC0	Crystal Structure of PAI-1 in Complex with Gallate Descriptor: 3,4,5-trihydroxybenzoic acid, Plasminogen activator inhibitor 1 Authors: Hong, Z.B, Lin, Z.H, Gong, L.H, Huang, M.D. Deposit date: 2012-12-09 Release date: 2013-12-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Crystal Structure of PAI-1 in Complex with Gallate To be Published
3R4L	Human very long half life Plasminogen Activator Inhibitor type-1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Yang, J, Zheng, H, Han, Q, Skrzypczak-Jankun, E, Jankun, J. Deposit date: 2011-03-17 Release date: 2011-11-02 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure. Int.J.Mol.Med., 29, 2012
2HI9	Crystal Structure of human native protein C inhibitor Descriptor: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor Authors: Li, W, Adams, T.E, Huntington, J.A. Deposit date: 2006-06-29 Release date: 2007-03-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of native protein C inhibitor provides insight into its multiple functions. J.Biol.Chem., 282, 2007
2HIJ	Crystal Structure of P14 Alanine Variant of Antithrombin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... Authors: Luis, S.A, Bock, S.C, Huntington, J.A. Deposit date: 2006-06-29 Release date: 2007-06-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal Structure of P14 Alanine Variant of Antithrombin To be Published
2ZV6	Crystal structure of human squamous cell carcinoma antigen 1 Descriptor: Serpin B3 Authors: Zheng, B, Matoba, Y, Katagiri, C, Hibino, T, Sugiyama, M. Deposit date: 2008-11-01 Release date: 2009-02-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of SCCA1 and insight about the interaction with JNK1 Biochem.Biophys.Res.Commun., 380, 2009
3STO	Serpin from the trematode Schistosoma Haematobium Descriptor: Serine protease inhibitor Authors: Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E. Deposit date: 2011-07-11 Release date: 2012-05-30 Last modified: 2013-01-23 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain. Acta Crystallogr.,Sect.D, 68, 2012
4IF8	Structure Of Vaspin Descriptor: SULFATE ION, Serpin A12 Authors: Kuettner, E.B, Strater, N, Heiker, J.T, Kloting, N, Kovacs, P, Schultz, S, Kern, M, Stumvoll, M, Bluher, M, Beck-Sickinger, A.G. Deposit date: 2012-12-14 Release date: 2013-02-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Vaspin inhibits kallikrein 7 by serpin mechanism Cell.Mol.Life Sci., 70, 2013
2H4R	Crystal structure of wildtype MENT in the native conformation Descriptor: Heterochromatin-associated protein MENT Authors: Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S. Deposit date: 2006-05-25 Release date: 2006-07-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
3T1P	Crystal structure of an alpha-1-antitrypsin trimer Descriptor: Alpha-1-antitrypsin Authors: Huntington, J.A, Yamasaki, M. Deposit date: 2011-07-22 Release date: 2011-08-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer. EMBO Rep., 12, 2011
4G8R	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 Descriptor: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION Authors: Stuckey, J.A, Lawrence, D.A, Li, S.-H. Deposit date: 2012-07-23 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
2H4Q	Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation Descriptor: Heterochromatin-associated protein MENT Authors: Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A. Deposit date: 2006-05-25 Release date: 2006-07-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2H4P	Crystal structure of wildtype MENT in the cleaved conformation Descriptor: Heterochromatin-associated protein MENT Authors: Buckle, A.M, McGowan, S, Irving, J.A, Whisstock, J.C. Deposit date: 2006-05-24 Release date: 2006-07-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
3CAA	CLEAVED ANTICHYMOTRYPSIN A347R Descriptor: ANTICHYMOTRYPSIN Authors: Lukacs, C.M, Christianson, D.W. Deposit date: 1997-08-18 Release date: 1998-02-25 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
3CVM	High resolution structure of a stable Plasminogen activator inhibitor type-1 in its protease cleaved form Descriptor: Plasminogen activator inhibitor 1 Authors: Jensen, J.K, Gettins, P.G.W. Deposit date: 2008-04-18 Release date: 2008-08-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.02 Å) Cite: High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: a new tool for detailed interaction studies and modeling. Protein Sci., 17, 2008
1WZ9	The 2.1 A structure of a tumour suppressing serpin Descriptor: Maspin precursor, SULFATE ION Authors: Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. Deposit date: 2005-03-03 Release date: 2005-03-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
6F4V	Crystal structure of cleaved Kallistatin complexed with heparin at 1.8 Angstrom resolution Descriptor: 1,2-ETHANEDIOL, 3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, CHLORIDE ION, ... Authors: Zhou, A, Wei, Z. Deposit date: 2017-11-30 Release date: 2018-12-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of human Kallistatin To Be Published
6F02	Crystal structure of human glycosylated kallistatin at 3.0 Angstrom resolution Descriptor: Kallistatin, SULFATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhou, A, Ma, L. Deposit date: 2017-11-17 Release date: 2018-12-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of human Kallistatin To Be Published
6F4U	Crystal structure of reactive loop cleaved kallistatin at 1.9 angstrom resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... Authors: Zhou, A, Wei, Z, Lin, F. Deposit date: 2017-11-30 Release date: 2018-12-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of human Kallistatin To Be Published
1XU8	The 2.8 A structure of a tumour suppressing serpin Descriptor: Maspin, SULFATE ION Authors: Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C. Deposit date: 2004-10-25 Release date: 2005-03-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
3ZHA	Molecular basis for the action of the collagen-specific chaperone Hsp47 SERPINH1 and its structure-specific client recognition. Descriptor: COLLAGEN MODEL PEPTIDE 18-T8R11, HSP47, SUCCINIC ACID Authors: Widmer, C, Gebauer, J.M, Baumann, U. Deposit date: 2012-12-20 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012

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