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2MMK
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BU of 2mmk by Molmil
Y41 and T47 phosphorylation of the Mengovirus Leader Protein: NMR Studies of the Phosphorylation of the Mengovirus Leader Protein Reveal Stabilization of Intermolecular Domain Interactions
Descriptor: Leader protein, ZINC ION
Authors:Bacot-Davis, V.R, Porter, F.W, Palmenberg, A.C.
Deposit date:2014-03-15
Release date:2014-10-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPase.
Proc.Natl.Acad.Sci.USA, 111, 2014
1FMO
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BU of 1fmo by Molmil
CRYSTAL STRUCTURE OF A POLYHISTIDINE-TAGGED RECOMBINANT CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH THE PEPTIDE INHIBITOR PKI(5-24) AND ADENOSINE
Descriptor: ADENOSINE, CAMP-DEPENDENT PROTEIN KINASE, HEAT STABLE RABBIT SKELETAL MUSCLE INHIBITOR PROTEIN
Authors:Narayana, N, Cox, S, Shaltiel, S, Taylor, S.S, Xuong, N.-H.
Deposit date:1997-07-08
Release date:1998-01-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
Biochemistry, 36, 1997
5HRK
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BU of 5hrk by Molmil
The crystal structure of AsfvPolX(H115F mutant): 1nt-gap(P) DNA2:dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A)-3'), ...
Authors:Chen, Y.Q, Zhang, J, Gan, J.H.
Deposit date:2016-01-23
Release date:2017-01-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
2OJ3
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BU of 2oj3 by Molmil
Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+)
Descriptor: COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ...
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-12
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
1NN8
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BU of 1nn8 by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus
Descriptor: MYRISTIC ACID, coat protein VP1, coat protein VP2, ...
Authors:He, Y, Mueller, S, Chipman, P.R, Bator, C.M, Peng, X, Bowman, V.D, Mukhopadhyay, S, Wimmer, E, Kuhn, R.J, Rossmann, M.G.
Deposit date:2003-01-13
Release date:2004-01-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Complexes of poliovirus serotypes with their common cellular receptor, CD155
J.Virol., 77, 2003
4FU3
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BU of 4fu3 by Molmil
CID of human RPRD1B
Descriptor: CHLORIDE ION, Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION
Authors:Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC)
Deposit date:2012-06-28
Release date:2012-08-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CID of human RPRD1B
TO BE PUBLISHED
3GLG
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BU of 3glg by Molmil
Crystal Structure of a Mutant (gammaT157A) E. coli Clamp Loader Bound to Primer-Template DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ...
Authors:Simonetta, K.R, Seyedin, S.N, Kuriyan, J.
Deposit date:2009-03-12
Release date:2009-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell(Cambridge,Mass.), 137, 2009
3GLF
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BU of 3glf by Molmil
Crystal Structure of the Ecoli Clamp Loader Bound to Primer-Template DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ...
Authors:Simonetta, K.R, Kuriyan, J.
Deposit date:2009-03-12
Release date:2009-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.388 Å)
Cite:The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell(Cambridge,Mass.), 137, 2009
4KN6
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BU of 4kn6 by Molmil
Crystal structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with 6-fluoro-3-hydroxy-2-pyrazinecarboxamide (T-705) ribose-5'-monophosphate
Descriptor: 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide, Hypoxanthine-guanine phosphoribosyltransferase
Authors:Naesens, L, Guddat, L, Keough, D, van Kuilenburg, A.B.P, Meijer, J, Vande Voorde, J, Balzarini, J.
Deposit date:2013-05-08
Release date:2013-08-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.728 Å)
Cite:Role of human hypoxanthine Guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir).
Mol.Pharmacol., 84, 2013
4NAC
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BU of 4nac by Molmil
Crystal Structure of the N-terminal Domain of p15RS
Descriptor: Regulation of nuclear pre-mRNA domain-containing protein 1A
Authors:Mei, K, Jin, Z, Ren, F, Wang, Y.
Deposit date:2013-10-22
Release date:2013-12-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal Structure of the N-terminal Domain of p15RS
To be Published
1SFK
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BU of 1sfk by Molmil
Core (C) protein from West Nile Virus, subtype Kunjin
Descriptor: CALCIUM ION, CHLORIDE ION, Core protein, ...
Authors:Dokland, T, Walsh, M, Mackenzie, J.M, Khromykh, A.A, Ee, K.-H, Wang, S.
Deposit date:2004-02-19
Release date:2004-08-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:West nile virus core protein; tetramer structure and ribbon formation
Structure, 12, 2004
2MMH
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BU of 2mmh by Molmil
Unphosphorylated Mengovirus Leader Protein: NMR Studies of the Phosphorylation of the Mengovirus Leader Protein Reveal Stabilization of Intermolecular Domain Interactions
Descriptor: Leader protein, ZINC ION
Authors:Bacot-Davis, V.R, Porter, F.W, Palmenberg, A.C.
Deposit date:2014-03-15
Release date:2014-10-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPase.
Proc.Natl.Acad.Sci.USA, 111, 2014
4WVY
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BU of 4wvy by Molmil
Double-heterohexameric rings of full-length Rvb1(ATP)/Rvb2(apo)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Hopfner, K.-P, Lakomek, K.
Deposit date:2014-11-08
Release date:2015-02-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural Basis for Dodecameric Assembly States and Conformational Plasticity of the Full-Length AAA+ ATPases Rvb1Rvb2.
Structure, 23, 2015
4XID
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BU of 4xid by Molmil
AntpHD with 15bp DNA duplex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
Authors:White, M.A, Zandarashvili, L, Iwahara, J.
Deposit date:2015-01-06
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
1OOP
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BU of 1oop by Molmil
The Crystal Structure of Swine Vesicular Disease Virus
Descriptor: Coat protein VP1, Coat protein VP2, Coat protein VP3, ...
Authors:Fry, E.E, Knowles, N.J, Newman, J.W.I, Wilsden, G, Rao, Z, King, A.M.Q, Stuart, D.I.
Deposit date:2003-03-04
Release date:2003-04-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Swine Vesicular Disease Virus and Implications for Host Adaptation
J.Virol., 77, 2003
7ZAN
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BU of 7zan by Molmil
Crystal Structure of human IL-17A in complex with IL-17RA and IL-17RC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, Interleukin-17A, ...
Authors:Rondeau, J.M, Goepfert, A.
Deposit date:2022-03-22
Release date:2022-10-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (5.061 Å)
Cite:IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling.
Cell Rep, 41, 2022
7K3L
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BU of 7k3l by Molmil
Crystal structure of dLC8 in complex with Panoramix TQ peptide
Descriptor: 1,2-ETHANEDIOL, Dynein light chain 1, cytoplasmic, ...
Authors:Wang, J, Patel, D.J.
Deposit date:2020-09-11
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
1NA1
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BU of 1na1 by Molmil
The structure of HRV14 when complexed with Pleconaril
Descriptor: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, Coat protein VP1, Coat protein VP2, ...
Authors:Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G.
Deposit date:2002-11-26
Release date:2003-12-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
2JZF
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BU of 2jzf by Molmil
NMR Conformer closest to the mean coordinates of the domain 513-651 of the SARS-CoV nonstructural protein nsp3
Descriptor: Replicase polyprotein 1ab
Authors:Chatterjee, A, Johnson, M.A, Serrano, P, Pedrini, B, Joseph, J, Saikatendu, K, Neuman, B, Stevens, R.C, Wilson, I.A, Buchmeier, M.J, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2008-01-04
Release date:2008-02-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold.
J.Virol., 83, 2009
4XIC
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BU of 4xic by Molmil
ANTPHD WITH 15BP di-thioate modified DNA DUPLEX
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
Authors:White, M.A, Zandarashvili, L, Iwahara, J.
Deposit date:2015-01-06
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
4WW4
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BU of 4ww4 by Molmil
Double-heterohexameric rings of full-length Rvb1(ADP)/Rvb2(ADP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Lakomek, K, Hopfner, K.-P.
Deposit date:2014-11-10
Release date:2015-02-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structural Basis for Dodecameric Assembly States and Conformational Plasticity of the Full-Length AAA+ ATPases Rvb1Rvb2.
Structure, 23, 2015
6CKC
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BU of 6ckc by Molmil
Structure of PRMT5:MEP50 in complex with LLY-283, a potent and selective inhibitor of PRMT5, with antitumor activity
Descriptor: 7-[(5R)-5-C-phenyl-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Methylosome protein 50, Protein arginine N-methyltransferase 5
Authors:Antonysamy, S.
Deposit date:2018-02-27
Release date:2018-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.
ACS Med Chem Lett, 9, 2018
4BBL
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BU of 4bbl by Molmil
Cryo-electron microscopy reconstruction of the helical part of influenza A virus ribonucleoprotein isolated from virions.
Descriptor: NUCLEOPROTEIN, RNA
Authors:Arranz, R, Coloma, R, Chichon, F.J, Conesa, J.J, Carrascosa, J.L, Valpuesta, J.M, Ortin, J, Martin-Benito, J.
Deposit date:2012-09-26
Release date:2012-12-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (18 Å)
Cite:The Structure of Native Influenza Virion Ribonucleoproteins
Science, 338, 2012
2OIH
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BU of 2oih by Molmil
Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+
Descriptor: HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-11
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2WV9
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BU of 2wv9 by Molmil
Crystal Structure of the NS3 protease-helicase from Murray Valley encephalitis virus
Descriptor: FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT, FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT
Authors:Assenberg, R, Mastrangelo, E, Walter, T.S, Verma, A, Milani, M, Owens, R.J, Stuart, D.I, Grimes, J.M, Mancini, E.J.
Deposit date:2009-10-15
Release date:2009-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of a Novel Conformational State of the Flavivirus Ns3 Protein: Implications for Polyprotein Processing and Viral Replication.
J.Virol., 83, 2009

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數據於2024-09-04公開中

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