2MMH
Unphosphorylated Mengovirus Leader Protein: NMR Studies of the Phosphorylation of the Mengovirus Leader Protein Reveal Stabilization of Intermolecular Domain Interactions
Summary for 2MMH
Entry DOI | 10.2210/pdb2mmh/pdb |
Related | 2M7Y 2MMG 2MMI 2MMK 2MML |
NMR Information | BMRB: 19084 |
Descriptor | Leader protein, ZINC ION (2 entities in total) |
Functional Keywords | animal viruses, positive-strand rna viruses, cardioviruses, leader, l, viral protein |
Biological source | Mengo virus |
Cellular location | Protein 2A: Host nucleus . Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3B: Virion . Protease 3C: Host cytoplasm . RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P12296 |
Total number of polymer chains | 1 |
Total formula weight | 8327.45 |
Authors | Bacot-Davis, V.R.,Porter, F.W.,Palmenberg, A.C. (deposition date: 2014-03-15, release date: 2014-10-15, Last modification date: 2023-06-14) |
Primary citation | Bacot-Davis, V.R.,Ciomperlik, J.J.,Basta, H.A.,Cornilescu, C.C.,Palmenberg, A.C. Solution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPase. Proc.Natl.Acad.Sci.USA, 111:15792-15797, 2014 Cited by PubMed: 25331866DOI: 10.1073/pnas.1411098111 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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