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1NHA
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BU of 1nha by Molmil
Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP-Binding Sites of RAP74 and CTD of RAP74, the subunit of Human TFIIF
Descriptor: Transcription initiation factor IIF, alpha subunit
Authors:Nguyen, B.D, Chen, H.T, Kobor, M.S, Greenblatt, J, Legault, P, Omichinski, J.G.
Deposit date:2002-12-19
Release date:2003-02-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP1-Binding Sites of RAP74 and Human TFIIB.
Biochemistry, 42, 2003
3BEP
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BU of 3bep by Molmil
Structure of a sliding clamp on DNA
Descriptor: 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ...
Authors:Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2007-11-19
Release date:2008-01-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of a sliding clamp on DNA
Cell(Cambridge,Mass.), 132, 2008
1NG0
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BU of 1ng0 by Molmil
The three-dimensional structure of Cocksfoot mottle virus at 2.7A resolution
Descriptor: CALCIUM ION, coat protein
Authors:Tars, K, Zeltins, A, Liljas, L.
Deposit date:2002-12-16
Release date:2003-02-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The three-dimensional structure of cocksfoot mottle virus at 2.7 A resolution.
Virology, 310, 2003
6VCD
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BU of 6vcd by Molmil
Cryo-EM structure of IRP2-FBXL5-SKP1 complex
Descriptor: F-box/LRR-repeat protein 5, FE2/S2 (INORGANIC) CLUSTER, Iron-responsive element binding protein 2, ...
Authors:Wang, H, Shi, H, Zheng, N.
Deposit date:2019-12-20
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster.
Mol.Cell, 78, 2020
6W4S
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BU of 6w4s by Molmil
Structure of apo human ferroportin in lipid nanodisc
Descriptor: Fab45D8 Heavy Chain, Fab45D8 Light Chain, Solute carrier family 40 member 1
Authors:Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A.
Deposit date:2020-03-11
Release date:2020-09-09
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
1TIV
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BU of 1tiv by Molmil
STRUCTURAL STUDIES OF HIV-1 TAT PROTEIN
Descriptor: HIV-1 TRANSACTIVATOR PROTEIN
Authors:Bayer, P, Kraft, M, Frank, R, Roesch, P.
Deposit date:1995-02-14
Release date:1995-07-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural studies of HIV-1 Tat protein.
J.Mol.Biol., 247, 1995
1ROQ
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BU of 1roq by Molmil
Extending the Family of UNCG-like Tetraloop Motifs: NMR Structure of a CACG Tetraloop from Coxsackievirus B3
Descriptor: 5'-R(*GP*GP*UP*AP*UP*CP*AP*CP*GP*GP*UP*AP*CP*C)-3'
Authors:Du, Z, Yu, J, Andino, R, James, T.L.
Deposit date:2003-12-02
Release date:2004-05-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Extending the Family of UNCG-like Tetraloop Motifs: NMR Structure of a CACG Tetraloop from Coxsackievirus B3
Biochemistry, 42, 2003
4DG2
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BU of 4dg2 by Molmil
Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20
Descriptor: MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Bastidas, A.C, Steichen, J.M, Taylor, S.S.
Deposit date:2012-01-24
Release date:2012-06-06
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
4DFX
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BU of 4dfx by Molmil
Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP
Descriptor: GLYCEROL, MAGNESIUM ION, MYRISTIC ACID, ...
Authors:Bastidas, A.C, Steichen, J.M, Taylor, S.S.
Deposit date:2012-01-24
Release date:2012-06-06
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
8T2S
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BU of 8t2s by Molmil
Structure of a group II intron ribonucleoprotein in the pre-branching (pre-1F) state
Descriptor: AMMONIUM ION, CALCIUM ION, Group II intron reverse transcriptase/maturase, ...
Authors:Xu, L, Liu, T, Chung, K, Pyle, A.M.
Deposit date:2023-06-06
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
4DFZ
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BU of 4dfz by Molmil
Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20
Descriptor: MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Bastidas, A.C, Steichen, J.M, Taylor, S.S.
Deposit date:2012-01-24
Release date:2012-06-06
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
5FX5
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BU of 5fx5 by Molmil
Novel inhibitors of human rhinovirus 3C protease
Descriptor: GLYCEROL, RHINOVIRUS 3C PROTEASE, TETRAETHYLENE GLYCOL, ...
Authors:Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q.
Deposit date:2016-02-24
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
4DG0
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BU of 4dg0 by Molmil
Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP
Descriptor: MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Bastidas, A.C, Steichen, J.M, Taylor, S.S.
Deposit date:2012-01-24
Release date:2012-06-06
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
5FX6
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BU of 5fx6 by Molmil
Novel inhibitors of human rhinovirus 3C protease
Descriptor: RHINOVIRUS 3C PROTEASE, ethyl (4R)-4-[[(2S,4S)-1-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)carbonylamino]butanoyl]-4-phenyl-pyrrolidin-2-yl]carbonylamino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate
Authors:Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q.
Deposit date:2016-02-24
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
2BHG
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BU of 2bhg by Molmil
3C protease from type A10(61) foot-and-mouth disease virus
Descriptor: FOOT-AND-MOUTH DISEASE VIRUS 3C PROTEASE
Authors:Birtley, J.R, Brick, P, Curry, S.
Deposit date:2005-01-10
Release date:2005-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease: New Insights Into Catalytic Mechanism and Cleavage Specificity
J.Biol.Chem., 280, 2005
1ZH1
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BU of 1zh1 by Molmil
Structure of the zinc-binding domain of HCV NS5A
Descriptor: ZINC ION, non-structural polyprotein
Authors:Tellinghuisen, T.L, Marcotrigiano, J, Rice, C.M.
Deposit date:2005-04-22
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase.
Nature, 435, 2005
4ZZZ
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BU of 4zzz by Molmil
Structure of human PARP1 catalytic domain bound to an isoindolinone inhibitor
Descriptor: 2-(3-methoxypropyl)-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide, GLYCEROL, POLY [ADP-RIBOSE] POLYMERASE 1, ...
Authors:Casale, E, Fasolini, M, Papeo, G, Posteri, H, Borghi, D, Busel, A.A, Caprera, F, Ciomei, M, Cirla, A, Corti, E, DAnello, M, Fasolini, M, Felder, E.R, Forte, B, Galvani, A, Isacchi, A, Khvat, A, Krasavin, M.Y, Lupi, R, Orsini, P, Perego, R, Pesenti, E, Pezzetta, D, Rainoldi, S, RiccardiSirtori, F, Scolaro, A, Sola, F, Zuccotto, F, Donati, D, Montagnoli, A.
Deposit date:2015-04-15
Release date:2015-08-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of 2-[1-(4,4-Difluorocyclohexyl)Piperidin-4-Yl]-6-Fluoro-3-Oxo-2,3-Dihydro-1H-Isoindole-4-Carboxamide (Nms-P118): A Potent, Orally Available and Highly Selective Parp- 1 Inhibitor for Cancer Therapy.
J.Med.Chem., 58, 2015
1S9S
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BU of 1s9s by Molmil
SOLUTION STRUCTURE OF MLV PSI SITE
Descriptor: MLV Psi encapsidation site
Authors:D'Souza, V, Dey, A, Habib, D, Summers, M.F.
Deposit date:2004-02-05
Release date:2004-04-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of the 101-nucleotide core encapsidation signal of the Moloney Murine Leukemia Virus.
J.Mol.Biol., 337, 2004
4QJH
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BU of 4qjh by Molmil
Crystal Structure of the Twister Ribozyme with the Nucleotide 5'- to the Cleavage Site Ordered at 4.1 A Resolution
Descriptor: MAGNESIUM ION, Twister Ribozyme
Authors:Eiler, D.R, Wang, J, Steitz, T.A.
Deposit date:2014-06-03
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
7KSE
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BU of 7kse by Molmil
Crystal structure of Prototype Foamy Virus Protease-Reverse Transcriptase CSH mutant (selenomethionine-labeled)
Descriptor: CALCIUM ION, Peptidase A9/Reverse transcriptase/RNase H
Authors:Harrison, J.J.E.K, Das, K, Ruiz, F.X, Arnold, E.
Deposit date:2020-11-21
Release date:2021-08-11
Last modified:2021-09-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT).
Viruses, 13, 2021
3FJ9
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BU of 3fj9 by Molmil
Crystal structure of F85W mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3FJB
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BU of 3fjb by Molmil
Crystal structure of V31I mutant of Human acidic fibroblast growth factor
Descriptor: Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
2WV9
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BU of 2wv9 by Molmil
Crystal Structure of the NS3 protease-helicase from Murray Valley encephalitis virus
Descriptor: FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT, FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT
Authors:Assenberg, R, Mastrangelo, E, Walter, T.S, Verma, A, Milani, M, Owens, R.J, Stuart, D.I, Grimes, J.M, Mancini, E.J.
Deposit date:2009-10-15
Release date:2009-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of a Novel Conformational State of the Flavivirus Ns3 Protein: Implications for Polyprotein Processing and Viral Replication.
J.Virol., 83, 2009
5NAN
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BU of 5nan by Molmil
Crystal Structure of human IL-17AF in complex with human IL-17RA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-galactopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
Authors:Rondeau, J.-M, Goepfert, A.
Deposit date:2017-02-28
Release date:2017-09-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.
Sci Rep, 7, 2017
5N92
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Crystal Structure of Human IL-17AF
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17A, Interleukin-17F
Authors:Rondeau, J.-M, Goepfert, A.
Deposit date:2017-02-24
Release date:2017-09-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.
Sci Rep, 7, 2017

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數據於2024-07-24公開中

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