PDB: 45817 resultsInfo pagesStatus searchChemie searchBIRD

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4PCZ	Crystal structure of a complex between R247G LlFPG mutant and a THF containing DNA Descriptor: DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ... Authors: Coste, F, Castaing, B. Deposit date: 2014-04-17 Release date: 2015-04-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization. Nucleic Acids Res., 42, 2014
6DBX	Cryo-EM structure of RAG in complex with 12-RSS substrate DNA Descriptor: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... Authors: Wu, H, Liao, M, Ru, H, Mi, W. Deposit date: 2018-05-03 Release date: 2018-08-01 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6W3Q	APE1 exonuclease substrate complex L104R Descriptor: CALCIUM ION, DNA-(apurinic or apyrimidinic site) lyase, GCTGATGCG(C7R), ... Authors: Freudenthal, B.D, Whitaker, A.M. Deposit date: 2020-03-09 Release date: 2020-06-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
4M9V	Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... Authors: Liu, Y, Olanrewaju, Y.O, Zhang, X, Cheng, X. Deposit date: 2013-08-15 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.969 Å) Cite: DNA recognition of 5-carboxylcytosine by a zfp57 mutant at an atomic resolution of 0.97 angstrom. Biochemistry, 52, 2013
8E4D	[U:Ag+:U] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice Descriptor: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*UP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... Authors: Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. Deposit date: 2022-08-18 Release date: 2023-04-05 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (4.19 Å) Cite: Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 35, 2023
8E4E	[T:Ag+:T] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice Descriptor: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*TP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*TP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... Authors: Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. Deposit date: 2022-08-18 Release date: 2023-04-05 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (4.19 Å) Cite: Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 35, 2023
8HMW	Double methyl modification on guanosine promotes unusual structural distortion and conformational transition in Z-DNA Descriptor: DNA (5'-D(*CP*GP*CP*(SJO)P*CP*G)-3') Authors: Lee, J.-H, Oh, K.-I. Deposit date: 2022-12-06 Release date: 2023-04-26 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Entropy-driven conformational transition of flexible Z-DNA to a novel non-B helix by double-methylated guanosine J Mol Liq, 2023
7LWA	Human Exonuclease 5 crystal structure (T88E) in complex with ssDNA and Mg Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Exonuclease V, ... Authors: Tsai, C.L, Tainer, J.A. Deposit date: 2021-02-28 Release date: 2021-07-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.85 Å) Cite: EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Mol.Cell, 81, 2021
7LW9	Human Exonuclease 5 crystal structure in complex with ssDNA, Sm, and Na Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*AP*TP*TP*GP*CP*TP*GP*AP*AP*GP*GP*G)-3'), ... Authors: Tsai, C.L, Tainer, J.A. Deposit date: 2021-02-28 Release date: 2021-07-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.71 Å) Cite: EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Mol.Cell, 81, 2021
7LW8	Human Exonuclease 5 crystal structure in complex with a ssDNA Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Exonuclease V, ... Authors: Tsai, C.L, Tainer, J.A. Deposit date: 2021-02-28 Release date: 2021-07-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.88 Å) Cite: EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Mol.Cell, 81, 2021
8EG4	[iU:Ag+:iU] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice Descriptor: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*(5IU)P*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(5IU)P*AP*CP*A*(AG))-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... Authors: Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. Deposit date: 2022-09-10 Release date: 2023-04-05 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (4.18 Å) Cite: Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 35, 2023
8DC2	Cryo-EM structure of CasLambda (Cas12l) bound to crRNA and DNA Descriptor: CasLambda, DNA NTS, DNA TS, ... Authors: Al-Shayeb, B, Skopintsev, P, Soczek, K, Doudna, J. Deposit date: 2022-06-15 Release date: 2022-12-14 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors. Cell, 185, 2022
4ZT0	Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA Authors: Jiang, F, Doudna, J.A. Deposit date: 2015-05-14 Release date: 2015-07-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Cas9-guide RNA complex preorganized for target DNA recognition. Science, 348, 2015
8W0A	Human DNA polymerase theta helicase domain in complex with ssDNA, dimer form Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DNA polymerase theta Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-02-13 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
1LAU	URACIL-DNA GLYCOSYLASE Descriptor: DNA (5'-D(*TP*TP*T)-3'), PROTEIN (URACIL-DNA GLYCOSYLASE (E.C.3.2.2.-)) Authors: Pearl, L.H, Savva, R. Deposit date: 1996-01-03 Release date: 1996-06-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The structural basis of specific base-excision repair by uracil-DNA glycosylase. Nature, 373, 1995
4KAZ	Crystal structure of RNase T in complex with a Y structured DNA Descriptor: DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2013-04-23 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways. Plos Biol., 12, 2014
3MDA	DNA polymerase lambda in complex with araC Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*CP*(CAR))-3'), DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ... Authors: Garcia-Diaz, M, Murray, M, Kunkel, T, Chou, K.M. Deposit date: 2010-03-30 Release date: 2010-04-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.031 Å) Cite: Interaction between DNA Polymerase lambda and anticancer nucleoside analogs. J.Biol.Chem., 285, 2010
4KB0	Crystal structure of RNase T in complex with a bluge DNA (Two nucleotide insertion CC ) Descriptor: DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2013-04-23 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.004 Å) Cite: Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways. Plos Biol., 12, 2014
4ZT9	Nuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolution Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA Authors: Jiang, F, Doudna, J.A. Deposit date: 2015-05-14 Release date: 2015-07-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A Cas9-guide RNA complex preorganized for target DNA recognition. Science, 348, 2015
5Z7D	p204HINab-dsDNA complex structure Descriptor: DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3'), Interferon-activable protein 204 Authors: Jin, T, Jiang, J, Xiao, T.S. Deposit date: 2018-01-28 Release date: 2019-01-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.5 Å) Cite: Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Res., 2021
5YX2	Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... Authors: Zhang, Z.M, Song, J. Deposit date: 2017-12-01 Release date: 2018-01-31 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.653 Å) Cite: Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
2PV0	DNA methyltransferase 3 like protein (DNMT3L) Descriptor: DNA (cytosine-5)-methyltransferase 3-like, ZINC ION Authors: Cheng, X. Deposit date: 2007-05-09 Release date: 2007-08-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.3 Å) Cite: DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature, 448, 2007
3O59	DNA polymerase D large subunit DP2(1-300) from Pyrococcus horikoshii Descriptor: DNA polymerase II large subunit Authors: Yokoyama, H, Shen, Y, Matsui, I. Deposit date: 2010-07-28 Release date: 2011-01-05 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Novel structure of an N-terminal domain that is crucial for the dimeric assembly and DNA-binding of an archaeal DNA polymerase D large subunit from Pyrococcus horikoshii Febs Lett., 585, 2011
6BRR	Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... Authors: Zhang, Z.M, Song, J. Deposit date: 2017-11-30 Release date: 2018-01-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
4LYL	Crystal structure of uracil-DNA glycosylase from cod (Gadus morhua) in complex with the proteinaceous inhibitor UGI Descriptor: Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor Authors: Assefa, N.G, Niiranen, L.M.K, Johnson, K.A, Leiros, H.-K.S, Smalas, A.O, Willassen, N.P, Moe, E. Deposit date: 2013-07-31 Release date: 2014-08-13 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structural and biophysical analysis of interactions between cod and human uracil-DNA N-glycosylase (UNG) and UNG inhibitor (Ugi). Acta Crystallogr.,Sect.D, 70, 2014

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