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3C0G
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BU of 3c0g by Molmil
CASK CaM-Kinase Domain- 3'-AMP complex, P1 form
Descriptor: Peripheral plasma membrane protein CASK, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate
Authors:Wahl, M.C.
Deposit date:2008-01-20
Release date:2008-04-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:CASK Functions as a Mg2+-independent neurexin kinase
Cell(Cambridge,Mass.), 133, 2008
5G40
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BU of 5g40 by Molmil
Crystal structure of adenylate kinase ancestor 4 with Zn and AMP-ADP bound
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINSE, ...
Authors:Nguyen, V, Kutter, S, English, J, Kern, D.
Deposit date:2016-05-03
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Evolutionary drivers of thermoadaptation in enzyme catalysis.
Science, 355, 2017
3C0I
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BU of 3c0i by Molmil
CASK CaM-Kinase Domain- 3'-AMP complex, P212121 form
Descriptor: Peripheral plasma membrane protein CASK, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate
Authors:Wahl, M.C.
Deposit date:2008-01-20
Release date:2008-04-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:CASK Functions as a Mg2+-independent neurexin kinase
Cell(Cambridge,Mass.), 133, 2008
5C1O
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BU of 5c1o by Molmil
Crystal structure of AMP-PNP complexed D-alanine-D-alanine ligase(DDL) from Yersinia pestis
Descriptor: D-alanine--D-alanine ligase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Tran, H.T, Kang, L.W, Hong, M.K.
Deposit date:2015-06-15
Release date:2016-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of D-alanine-D-alanine ligase from Yersinia pestis: nucleotide phosphate recognition by the serine loop.
Acta Crystallogr D Struct Biol, 72, 2016
3MVJ
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BU of 3mvj by Molmil
Human cyclic AMP-dependent protein kinase PKA inhibitor complex
Descriptor: (3R)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Pandit, J, Vajdos, F.
Deposit date:2010-05-04
Release date:2010-06-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Design of selective, ATP-competitive inhibitors of Akt.
J.Med.Chem., 53, 2010
6R8U
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BU of 6r8u by Molmil
Escherichia coli AGPase in complex with AMP.
Descriptor: ADENOSINE MONOPHOSPHATE, Glucose-1-phosphate adenylyltransferase
Authors:Cifuente, J.O, Comino, N, D'Angelo, C, Marina, A, Gil-Carton, D, Albesa-Jove, D, Guerin, M.E.
Deposit date:2019-04-02
Release date:2020-02-05
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM
Biorxiv, 2020
1YKD
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BU of 1ykd by Molmil
Crystal Structure of the Tandem GAF Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand-Binding and Dimerization
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, adenylate cyclase
Authors:Martinez, S.E, Bruder, S, Schultz, A, Zheng, N, Schultz, J.E, Beavo, J.A, Linder, J.U.
Deposit date:2005-01-17
Release date:2005-02-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization
Proc.Natl.Acad.Sci.USA, 102, 2005
3KXW
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BU of 3kxw by Molmil
The crystal structure of fatty acid AMP ligase from Legionella pneumophila
Descriptor: 5'-O-[(S)-(dodecanoyloxy)(hydroxy)phosphoryl]adenosine, Saframycin Mx1 synthetase B
Authors:Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2009-12-04
Release date:2010-03-16
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Structural and Functional Studies of Fatty Acyl Adenylate Ligases from E. coli and L. pneumophila.
J.Mol.Biol., 406, 2011
1Z84
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BU of 1z84 by Molmil
X-ray structure of galt-like protein from arabidopsis thaliana at5g18200
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ZINC ION, ...
Authors:Mccoy, J.G, Bitto, E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2005-03-29
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure and Mechanism of an ADP-Glucose Phosphorylase from Arabidopsis thaliana
Biochemistry, 45, 2006
3LCB
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BU of 3lcb by Molmil
The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli.
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isocitrate dehydrogenase [NADP], ...
Authors:Zheng, J, Jia, Z.
Deposit date:2010-01-10
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
5KLZ
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BU of 5klz by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) AMP catalytic product complex
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1
Authors:Maize, K.M, Finzel, B.C.
Deposit date:2016-06-26
Release date:2017-06-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
Mol. Pharm., 14, 2017
2CPK
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BU of 2cpk by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CYCLIC ADENOSINE MONOPHOSPHATE-DEPENDENT PROTEIN KINASE
Descriptor: PEPTIDE INHIBITOR 20-MER, cAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT
Authors:Knighton, D.R, Zheng, J, Teneyck, L.F, Ashford, V.A, Xuong, N.-H, Taylor, S.S, Sowadski, J.M.
Deposit date:1992-10-21
Release date:1993-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.
Science, 253, 1991
2EWN
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BU of 2ewn by Molmil
Ecoli Biotin Repressor with co-repressor analog
Descriptor: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, BirA bifunctional protein
Authors:Wood, Z.A, Weaver, L.H, Matthews, B.W.
Deposit date:2005-11-04
Release date:2006-02-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution.
J.Mol.Biol., 357, 2006
4Q86
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BU of 4q86 by Molmil
YcaO with AMP Bound
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Ribosomal protein S12 methylthiotransferase accessory factor YcaO
Authors:Chekan, J.R, Nair, S.K.
Deposit date:2014-04-25
Release date:2014-08-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis.
Nat.Chem.Biol., 10, 2014
3EPS
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BU of 3eps by Molmil
The crystal structure of isocitrate dehydrogenase kinase/phosphatase from E. coli
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ...
Authors:Zheng, J, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2008-09-29
Release date:2010-04-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
3ETC
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BU of 3etc by Molmil
2.1 A structure of acyl-adenylate synthetase from Methanosarcina acetivorans containing a link between Lys256 and Cys298
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMP-binding protein, FORMYL GROUP, ...
Authors:Shah, M.B, Gulick, A.M, Smith, K.S, Ingram-Smith, C.
Deposit date:2008-10-07
Release date:2009-07-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The 2.1 A crystal structure of an acyl-CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl-binding pocket for small branched acyl substrates.
Proteins, 77, 2009
5COT
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BU of 5cot by Molmil
Structure and mechanism of a eukaryal nick-sealing RNA ligase
Descriptor: ADENOSINE MONOPHOSPHATE, Naegleria gruberi RNA ligase, UNKNOWN ATOM OR ION
Authors:Unciuleac, M.C, Goldgur, Y, Shuman, S.
Deposit date:2015-07-20
Release date:2015-10-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
5KST
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BU of 5kst by Molmil
Stationary phase Survival protein E (SurE) from Xylella fastidiosa- XfSurE-TSAmp (Tetramer Smaller - crystallization with 3'AMP).
Descriptor: 5'-nucleotidase SurE, IODIDE ION, MANGANESE (II) ION, ...
Authors:Machado, A.T.P, Fonseca, E.M.B, Dos Reis, M.A, Saraiva, A.M, Dos Santos, C.A, De Toledo, M.A.S, Polikarpov, I, De Souza, A.P, Aparicio, R, Iulek, J.
Deposit date:2016-07-09
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.759 Å)
Cite:Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X-ray scattering studies, and normal mode analysis.
Proteins, 85, 2017
4O1P
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BU of 4o1p by Molmil
Crystal Structure of RNase L in complex with 2-5A and AMP-PNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonuclease L, ...
Authors:Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
Deposit date:2013-12-16
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
1VP6
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BU of 1vp6 by Molmil
M.loti ion channel cylic nucleotide binding domain
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel
Authors:Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H.
Deposit date:2004-10-14
Release date:2004-10-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.
Cell(Cambridge,Mass.), 119, 2004
5TSH
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BU of 5tsh by Molmil
PilB from Geobacter metallireducens bound to AMP-PNP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:McCallum, M, Tammam, S, Khan, A, Burrows, L, Howell, P.L.
Deposit date:2016-10-28
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The molecular mechanism of the type IVa pilus motors.
Nat Commun, 8, 2017
6GZO
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BU of 6gzo by Molmil
Crystal structure of NadR protein in complex with NAD and AMP-PNP
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Nicotinamide-nucleotide adenylyltransferase NadR family / Ribosylnicotinamide kinase, PHOSPHATE ION, ...
Authors:Singh, R, Stetsenko, A, Jaehme, M, Guskov, A, Slotboom, D.J.
Deposit date:2018-07-04
Release date:2019-07-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Functional Characterization of NadR fromLactococcus lactis.
Molecules, 25, 2020
4JLX
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BU of 4jlx by Molmil
Structure of porcine cyclic GMP-AMP synthase (cGAS)
Descriptor: GLYCEROL, MALONATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Civril, F, Hopfner, K.P.
Deposit date:2013-03-13
Release date:2013-06-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural mechanism of cytosolic DNA sensing by cGAS
Nature, 498, 2013
4FT8
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BU of 4ft8 by Molmil
E. coli Catabolite Activator Protein with Cobalt and Sulfate Ligands
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT (II) ION, Catabolite gene activator, ...
Authors:Rao, R, Lawson, C.L.
Deposit date:2012-06-27
Release date:2013-12-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.966 Å)
Cite:Structure of catabolite activator protein with cobalt(II) and sulfate.
Acta Crystallogr F Struct Biol Commun, 70, 2014
3SN9
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BU of 3sn9 by Molmil
Fic protein from NEISSERIA MENINGITIDIS mutant S182A/E186A in complex with AMPPNP
Descriptor: Cell filamentation protein Fic-related protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Goepfert, A, Stanger, F, Schirmer, T.
Deposit date:2011-06-29
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins.
Nature, 482, 2012

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數據於2024-08-28公開中

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