6ZAB
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![BU of 6zab by Molmil](/molmil-images/mine/6zab) | Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (P6422 space group) | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Morera, S, Naretto, A, Vigouroux, A, Legrand, P. | Deposit date: | 2020-06-05 | Release date: | 2020-12-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum. Nucleic Acids Res., 49, 2021
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6ZA7
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![BU of 6za7 by Molmil](/molmil-images/mine/6za7) | Structure of the apo transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ... | Authors: | Morera, S, Vigouroux, A, Legrand, P. | Deposit date: | 2020-06-04 | Release date: | 2020-12-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum. Nucleic Acids Res., 49, 2021
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7ET5
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![BU of 7et5 by Molmil](/molmil-images/mine/7et5) | Crystal structure of Arabidopsis TEM1 AP2 domain | Descriptor: | AP2/ERF and B3 domain-containing transcription repressor TEM1, SULFATE ION | Authors: | Hu, H, Du, J. | Deposit date: | 2021-05-12 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.052 Å) | Cite: | TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ET6
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![BU of 7et6 by Molmil](/molmil-images/mine/7et6) | Crystal structure of Arabidopsis TEM1 B3-DNA complex | Descriptor: | AP2/ERF and B3 domain-containing transcription repressor TEM1, FT-RY14-F, FT-RY14-R | Authors: | Hu, H, Du, J. | Deposit date: | 2021-05-12 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ET4
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![BU of 7et4 by Molmil](/molmil-images/mine/7et4) | Crystal structure of Arabidopsis TEM1 AP2 domain | Descriptor: | AP2/ERF and B3 domain-containing transcription repressor TEM1, DNA (12-mer) | Authors: | Hu, H, Du, J. | Deposit date: | 2021-05-12 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis. Proc.Natl.Acad.Sci.USA, 118, 2021
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1PPG
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![BU of 1ppg by Molmil](/molmil-images/mine/1ppg) | The refined 2.3 angstroms crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor | Descriptor: | HUMAN LEUKOCYTE ELASTASE, MEO-SUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYLKETONE, alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bode, W, Wei, A-Z. | Deposit date: | 1991-10-24 | Release date: | 1994-01-31 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor. FEBS Lett., 234, 1988
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2OVM
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![BU of 2ovm by Molmil](/molmil-images/mine/2ovm) | Progesterone Receptor with Bound Asoprisnil and a Peptide from the Co-Repressor NCoR | Descriptor: | 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME, NCoR, Progesterone receptor | Authors: | Madauss, K.P, Deng, S.-J, Short, S.A, Stewart, E.L, Williams, S.P. | Deposit date: | 2007-02-14 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator. Mol.Endocrinol., 21, 2007
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2OVH
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![BU of 2ovh by Molmil](/molmil-images/mine/2ovh) | Progesterone Receptor with Bound Asoprisnil and a Peptide from the Co-Repressor SMRT | Descriptor: | 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME, Progesterone receptor, SMRT peptide | Authors: | Madauss, K.P, Deng, S.-J, Short, S.A, Stewart, E.L, Williams, S.P. | Deposit date: | 2007-02-13 | Release date: | 2007-03-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator. Mol.Endocrinol., 21, 2007
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5YEL
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![BU of 5yel by Molmil](/molmil-images/mine/5yel) | Crystal structure of CTCF ZFs6-11-gb7CSE | Descriptor: | DNA (26-MER), Transcriptional repressor CTCF, ZINC ION | Authors: | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | Deposit date: | 2017-09-18 | Release date: | 2017-11-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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5KWQ
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![BU of 5kwq by Molmil](/molmil-images/mine/5kwq) | Two Tandem RRM Domains of FBP-Interacting Repressor (FIR), also Known as PUF60 | Descriptor: | Poly(U)-binding-splicing factor PUF60 | Authors: | Crichlow, G.V, Yang, Y, Zhou, H, Lolis, E.J, Braddock, D.T. | Deposit date: | 2016-07-18 | Release date: | 2017-08-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60. Plos One, 15, 2020
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6YS3
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![BU of 6ys3 by Molmil](/molmil-images/mine/6ys3) | Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Schulte, L, Reitz, J, Kudlinzki, D, Hodirnau, V.V, Frangakis, A, Schwalbe, H. | Deposit date: | 2020-04-20 | Release date: | 2020-09-30 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide Nat Commun, 2020
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7ZRA
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![BU of 7zra by Molmil](/molmil-images/mine/7zra) | Crystal structure of E.coli LexA in complex with nanobody NbSOS1(Nb14497) | Descriptor: | 1,2-ETHANEDIOL, LexA repressor, Nanobody NbSOS1 (Nb14497) | Authors: | Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L. | Deposit date: | 2022-05-04 | Release date: | 2022-10-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway. Structure, 30, 2022
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7RMW
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![BU of 7rmw by Molmil](/molmil-images/mine/7rmw) | Crystal structure of B. subtilis PurR bound to ppGpp | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, Pur operon repressor | Authors: | Schumacher, M.A. | Deposit date: | 2021-07-28 | Release date: | 2021-12-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus. Nucleic Acids Res., 50, 2022
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8C7U
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6O8L
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6O8K
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![BU of 6o8k by Molmil](/molmil-images/mine/6o8k) | Crystal Structure of apo and reduced Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulatus. | Descriptor: | GLYCEROL, SULFATE ION, Transcriptional regulator, ... | Authors: | Capdevila, D.A, Gonzalez-Gutierrez, G, Giedroc, D.P. | Deposit date: | 2019-03-11 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural basis for persulfide-sensing specificity in a transcriptional regulator. Nat.Chem.Biol., 17, 2021
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5Y7Y
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![BU of 5y7y by Molmil](/molmil-images/mine/5y7y) | Crystal structure of AhRR/ARNT complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Aryl hydrocarbon receptor repressor, GLYCEROL | Authors: | Sakurai, S, Shimizu, T, Ohto, U. | Deposit date: | 2017-08-18 | Release date: | 2017-09-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription. J. Biol. Chem., 292, 2017
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1ZAY
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![BU of 1zay by Molmil](/molmil-images/mine/1zay) | PURINE REPRESSOR-HYPOXANTHINE-MODIFIED-PURF-OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*TP*(1AP)P*TP*TP*TP*TP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Zheleznova, E.E, Brennan, R.G. | Deposit date: | 1998-12-16 | Release date: | 1999-12-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Roles of Exocyclic Groups in the Central Base-Pair Step in Modulating the Affinity of PurR for its Operator To be Published
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5YEH
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![BU of 5yeh by Molmil](/molmil-images/mine/5yeh) | Crystal structure of CTCF ZFs4-8-eCBS | Descriptor: | DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*CP*CP*GP*CP*TP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*AP*GP*CP*GP*GP*AP*AP*AP*CP*CP*G)-3'), Transcriptional repressor CTCF, ... | Authors: | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | Deposit date: | 2017-09-17 | Release date: | 2017-11-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.328 Å) | Cite: | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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5YEF
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![BU of 5yef by Molmil](/molmil-images/mine/5yef) | Crystal structure of CTCF ZFs2-8-Hs5-1aE | Descriptor: | DNA (27-MER), Transcriptional repressor CTCF, ZINC ION | Authors: | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | Deposit date: | 2017-09-17 | Release date: | 2017-11-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.807 Å) | Cite: | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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6CRO
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![BU of 6cro by Molmil](/molmil-images/mine/6cro) | |
8PVZ
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5YZZ
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![BU of 5yzz by Molmil](/molmil-images/mine/5yzz) | AtVAL1 B3 domain in complex with 13bp-DNA | Descriptor: | B3 domain-containing transcription repressor VAL1, DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*A)-3') | Authors: | Wu, B.X, Zhang, M.M. | Deposit date: | 2017-12-17 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structural insight into the role of VAL1 B3 domain for targeting to FLC locus in Arabidopsis thaliana. Biochem. Biophys. Res. Commun., 2018
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7ZPN
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![BU of 7zpn by Molmil](/molmil-images/mine/7zpn) | Crystal Structure of IscR from Dinoroseobacter shibae | Descriptor: | GLYCEROL, HTH-type transcriptional regulator, SULFATE ION | Authors: | Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E. | Deposit date: | 2022-04-28 | Release date: | 2023-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes To Be Published
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8D8I
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![BU of 8d8i by Molmil](/molmil-images/mine/8d8i) | Crystal structure of Reverb alpha in complex with synthetic agonist | Descriptor: | (4S)-6-[([1,1'-biphenyl]-2-yl)oxy]-3-chloro[1,2,4]triazolo[4,3-b]pyridazine, Nuclear receptor corepressor 1, Nuclear receptor subfamily 1 group D member 1 | Authors: | Ronin, C, Ciesielski, F, Hegazy, L, Burris, P.T. | Deposit date: | 2022-06-08 | Release date: | 2022-12-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.504 Å) | Cite: | Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB. Nat Commun, 13, 2022
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