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8V86
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Alpha7-nicotinic acetylcholine receptor bound to GAT107
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ...
Authors:Burke, S.M, Noviello, C.M, Hibbs, R.E.
Deposit date:2023-12-04
Release date:2024-02-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.47 Å)
Cite:Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.
Cell, 187, 2024
8V80
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BU of 8v80 by Molmil
Alpha7-nicotinic acetylcholine receptor bound to epibatidine and (-)-TQS
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3aR,4S,9bS)-4-(naphthalen-1-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ...
Authors:Burke, S.M, Noviello, C.M, Hibbs, R.E.
Deposit date:2023-12-04
Release date:2024-02-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.
Cell, 187, 2024
8V6V
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BU of 8v6v by Molmil
Cryo-EM structure of doubly-bound SNF2h-nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
Authors:Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
Deposit date:2023-12-03
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
8XAB
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BU of 8xab by Molmil
Crystal structure of Ubl1 domain of nonstructural protein 3 of SARS-CoV-2
Descriptor: GLYCEROL, Papain-like protease nsp3
Authors:Li, Y, Ke, Z.
Deposit date:2023-12-03
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:N-terminus of SARS-CoV-2 Nsp3 Interrupts RNA-driven Phase Separation of N Protein by Displacing RNA
To Be Published
8RB5
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BU of 8rb5 by Molmil
Structure of the three-fold capsomer of the PNMA2 capsid
Descriptor: Paraneoplastic antigen Ma2 homolog
Authors:Erlendsson, S, Xu, J, Shepherd, J.D, Briggs, J.A.G.
Deposit date:2023-12-03
Release date:2024-02-14
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome.
Cell, 187, 2024
8RB7
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BU of 8rb7 by Molmil
Structure of the two-fold capsomer of the PNMA2 capsid
Descriptor: Paraneoplastic antigen Ma2 homolog
Authors:Erlendsson, S, Xu, J, Shepherd, J.D, Briggs, J.A.G.
Deposit date:2023-12-03
Release date:2024-02-14
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome.
Cell, 187, 2024
8RB4
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BU of 8rb4 by Molmil
Structure of the five-fold capsomer of the PNMA2 capsid
Descriptor: Paraneoplastic antigen Ma2 homolog
Authors:Erlendsson, S, Xu, J, Shepherd, J.D, Briggs, J.A.G.
Deposit date:2023-12-02
Release date:2024-02-14
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome.
Cell, 187, 2024
8RB3
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BU of 8rb3 by Molmil
Structure of the PNMA2 capsid
Descriptor: Paraneoplastic antigen Ma2 homolog
Authors:Erlendsson, S, Xu, J, Shepherd, J.D, Briggs, J.A.G.
Deposit date:2023-12-02
Release date:2024-02-14
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome.
Cell, 187, 2024
8RAS
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BU of 8ras by Molmil
Plastid-encoded RNA polymerase transcription elongation complex
Descriptor: DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Webster, M.W, Pramanick, I, Vergara-Cruces, A.
Deposit date:2023-12-01
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
8RAK
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BU of 8rak by Molmil
Crystal structure of human Dihydroorotate Dehydrogenase in complex with the inhibitor 2-Hydroxy-N-(2-isopropyl-5-methyl-4-(pyridin-4-yloxy)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide
Descriptor: ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Alberti, M, Miggiano, R.
Deposit date:2023-12-01
Release date:2024-06-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent.
Acta Crystallogr D Struct Biol, 80, 2024
8V62
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BU of 8v62 by Molmil
Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 1D10 and 4C06
Descriptor: Camelid nanobody 1D10, Camelid nanobody 4C06, Fusion glycoprotein F0
Authors:Johnson, N.J, Ramamohan, A.R, McLellan, J.S.
Deposit date:2023-12-01
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies.
Nat Commun, 15, 2024
8V6J
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BU of 8v6j by Molmil
DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.11 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6I
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BU of 8v6i by Molmil
DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (14.06 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6G
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BU of 8v6g by Molmil
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.16 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6H
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BU of 8v6h by Molmil
DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.11 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5K
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BU of 8v5k by Molmil
Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 4C03 and 4C06
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid Nanobody 4C03, Camelid Nanobody 4C06, ...
Authors:Johnson, N.V, Ramamohan, A.R, McLellan, J.S.
Deposit date:2023-11-30
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies.
Nat Commun, 15, 2024
8V5O
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BU of 8v5o by Molmil
Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8.99 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5N
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BU of 8v5n by Molmil
Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8.56 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5A
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BU of 8v5a by Molmil
Prefusion-stabilized Respirovirus type 3 Fusion protein
Descriptor: Camelid nanobody 4C06, Fusion glycoprotein F0
Authors:Johnson, N.V, McLellan, J.S.
Deposit date:2023-11-30
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein.
Nat Commun, 15, 2024
8V5M
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BU of 8v5m by Molmil
Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (9.22 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8X9G
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BU of 8x9g by Molmil
Crystal structure of CO dehydrogenase mutant in complex with BV
Descriptor: 1-(phenylmethyl)-4-[1-(phenylmethyl)pyridin-1-ium-4-yl]pyridin-1-ium, Carbon monoxide dehydrogenase 2, FE(4)-NI(1)-S(4) CLUSTER, ...
Authors:Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y.
Deposit date:2023-11-30
Release date:2024-04-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity.
Nat Commun, 15, 2024
8X9H
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BU of 8x9h by Molmil
Crystal structure of CO dehydrogenase mutant (F41C)
Descriptor: Carbon monoxide dehydrogenase 2, FE (III) ION, FE(4)-NI(1)-S(4) CLUSTER, ...
Authors:Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y.
Deposit date:2023-11-30
Release date:2024-04-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity.
Nat Commun, 15, 2024
8X9F
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BU of 8x9f by Molmil
Crystal structure of CO dehydrogenase mutant in complex with EV
Descriptor: 1,2-ETHANEDIOL, 1-ethyl-4-(1-ethylpyridin-1-ium-4-yl)pyridin-1-ium, Carbon monoxide dehydrogenase 2, ...
Authors:Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y.
Deposit date:2023-11-30
Release date:2024-04-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity.
Nat Commun, 15, 2024
8X9E
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BU of 8x9e by Molmil
Crystal structure of CO dehydrogenase mutant with increased affinity for electron mediators in low PEG concentration
Descriptor: 1,2-ETHANEDIOL, Carbon monoxide dehydrogenase 2, FE (III) ION, ...
Authors:Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y.
Deposit date:2023-11-30
Release date:2024-04-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity.
Nat Commun, 15, 2024
8X9D
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BU of 8x9d by Molmil
Crystal structure of CO dehydrogenase mutant with increased affinity for electron mediators in high PEG concentration
Descriptor: Carbon monoxide dehydrogenase 2, FE (III) ION, FE(4)-NI(1)-S(4) CLUSTER, ...
Authors:Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y.
Deposit date:2023-11-30
Release date:2024-04-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity.
Nat Commun, 15, 2024

222415

數據於2024-07-10公開中

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