PDB: 4050 resultsInfo pagesStatus searchChemie searchBIRD

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6EAU	Crystallographic structure of the octapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 21 21 21. Descriptor: CALCIUM ION, CYS-THR-LYS-SER-ILE-PRO-PRO-CYS, Cationic trypsin, ... Authors: Fernandes, J.C, Valadares, N.F, Freitas, S.M, Barbosa, J.A.R.G. Deposit date: 2018-08-03 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Crystallographic structure of the octapeptide derived from the BTCI inhibitor bound to beta-trypsin in space group P 21 21 21. To Be Published
5PTP	STRUCTURE OF HYDROLASE (SERINE PROTEINASE) Descriptor: BETA TRYPSIN, CALCIUM ION Authors: Stroud, R.M, Finer-Moore, J. Deposit date: 1997-03-31 Release date: 1997-07-07 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. Proteins, 12, 1992
6ZQ2	Cationic trypsin in complex with a derivative of benzamidine Descriptor: CALCIUM ION, Cationic trypsin, D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide, ... Authors: Sandner, A, Heine, A, Klebe, G. Deposit date: 2020-07-09 Release date: 2021-07-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.29 Å) Cite: Cationic trypsin in complex with a derivative of benzamidine To be published
7AL8	Structure of ATSI with bovine trypsin Descriptor: CALCIUM ION, Cationic trypsin, SULFATE ION, ... Authors: Reverter, D, Covaleda, G. Deposit date: 2020-10-05 Release date: 2021-10-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structure of ATSI with bovine trypsin To Be Published
8JOK	Crystal structure of V30L mutated human transthyretin Descriptor: MAGNESIUM ION, Transthyretin Authors: Mizuguchi, M, Yamada, S, Obita, T. Deposit date: 2023-06-07 Release date: 2024-04-17 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis. Febs J., 291, 2024
8JNU	Crystal structure of V30G mutated human transthyretin Descriptor: MAGNESIUM ION, Transthyretin Authors: Mizuguchi, M, Yamada, S, Obita, T. Deposit date: 2023-06-06 Release date: 2024-04-17 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis. Febs J., 291, 2024
8JQW	Crystal structure of V30I mutated human transthyretin Descriptor: MAGNESIUM ION, Transthyretin Authors: Mizuguchi, M, Yamada, S, Obita, T. Deposit date: 2023-06-15 Release date: 2024-04-17 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis. Febs J., 291, 2024
8U5F	Crystal Structure of Trypsinized Clostridium perfringens Enterotoxin Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Heat-labile enterotoxin B chain, ... Authors: Kapoor, S, Ogbu, C.P, Vecchio, A.J. Deposit date: 2023-09-12 Release date: 2023-09-27 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin. Toxins, 15, 2023
6QIH	Pancreatic Bovine Trypsin with a boronic acid inhibitor Descriptor: CALCIUM ION, Cationic trypsin, DI(HYDROXYETHYL)ETHER, ... Authors: Santos-Silva, T, Correia, H.D. Deposit date: 2019-01-18 Release date: 2020-02-05 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Pancreatic Bovine Trypsin with a boronic acid inhibitor To Be Published
8HNR	Molecular structure of Kunitz-type trypsin inhibitor from seeds of Albizia procera Descriptor: Kunitz-type trypsin inhibitor Authors: Mehmood, S, Thirup, S.S, Saeed, A, Rafiq, M, Khaliq, B, Akrem, A. Deposit date: 2022-12-08 Release date: 2023-02-01 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Molecular structure of Kunitz-type trypsin inhibitor from seeds of Albizia procera To Be Published
5GXP	Cationic Trypsin With GOL/PGE as Dimer at pH 4.6 Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL, ... Authors: Manohar, R, Gunasekaran, K. Deposit date: 2016-09-19 Release date: 2016-11-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Cationic Trypsin With GOL/PGE as Dimer at pH 4.6 To Be Published
2KAI	REFINED 2.5 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF THE COMPLEX FORMED BY PORCINE KALLIKREIN A AND THE BOVINE PANCREATIC TRYPSIN INHIBITOR. CRYSTALLIZATION, PATTERSON SEARCH, STRUCTURE DETERMINATION, REFINEMENT, STRUCTURE AND COMPARISON WITH ITS COMPONENTS AND WITH THE BOVINE TRYPSIN-PANCREATIC TRYPSIN INHIBITOR COMPLEX Descriptor: BOVINE PANCREATIC TRYPSIN INHIBITOR, KALLIKREIN A Authors: Bode, W, Chen, Z. Deposit date: 1984-05-21 Release date: 1984-07-19 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin-pancreatic trypsin inhibitor complex J.Mol.Biol., 164, 1983
4MTB	Bovine trypsin in complex with small molecule inhibitor Descriptor: (2R)-2-amino-N-{(2S)-1-[(4-carbamimidoylbenzyl)amino]-1-oxopropan-2-yl}-4-(4-hydroxyphenyl)butanamide, CALCIUM ION, Cationic trypsin, ... Authors: Wagner, S, Heine, A, Steinmetzer, T. Deposit date: 2013-09-19 Release date: 2014-12-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.22 Å) Cite: X-ray structure of trypsin-inhibitor-complex To be Published
6HAR	Crystal structure of Mesotrypsin in complex with APPI-M17C/I18F/F34C Descriptor: 1,2-ETHANEDIOL, Amyloid-beta A4 protein, CALCIUM ION, ... Authors: Shahar, A, Cohen, I, Radisky, E, Papo, N. Deposit date: 2018-08-08 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.497 Å) Cite: Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin. J.Biol.Chem., 294, 2019
3TPI	THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS Descriptor: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ISOLEUCINE, ... Authors: Huber, R, Bode, W, Deisenhofer, J, Schwager, P. Deposit date: 1982-09-27 Release date: 1983-01-18 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors Acta Crystallogr.,Sect.B, 39, 1983
4YLQ	Crystal Structure of a FVIIa-Trypsin Chimera (FT) in Complex with Soluble Tissue Factor Descriptor: CALCIUM ION, Coagulation factor VII, N-PROPANOL, ... Authors: Sorensen, A.B, Svensson, L.A, Gandhi, P.S. Deposit date: 2015-03-05 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity. J.Biol.Chem., 291, 2016
4ZMA	Crystal Structure of a FVIIa-Trypsin Chimera (ST) in Complex with Soluble Tissue Factor Descriptor: CACODYLATE ION, CALCIUM ION, Coagulation factor VII, ... Authors: Sorensen, A.B, Svensson, L.A, Gandhi, P.S. Deposit date: 2015-05-02 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity. J.Biol.Chem., 291, 2016
2TGP	THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS Descriptor: CALCIUM ION, SULFATE ION, TRYPSIN INHIBITOR, ... Authors: Huber, R, Bode, W, Deisenhofer, J, Schwager, P. Deposit date: 1982-09-27 Release date: 1983-01-18 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors Acta Crystallogr.,Sect.B, 39, 1983
6XYK	Crystal structure of bovine trypsin at room temperature. Descriptor: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... Authors: Jensen, M. Deposit date: 2020-01-30 Release date: 2021-01-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.50000036 Å) Cite: Femtosecond structure of bovine trypsin at room temperature To Be Published
2TPI	ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY Descriptor: ISOLEUCINE, MERCURY (II) ION, TRYPSIN INHIBITOR, ... Authors: Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R. Deposit date: 1981-10-26 Release date: 1982-03-04 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.1 Å) Cite: On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography Acta Crystallogr.,Sect.B, 38, 1982
1UUB	Solution structure of a truncated bovine pancreatic trypsin inhibitor mutant, 3-58 BPTI (K15R, R17A, R42S) Descriptor: BOVINE PANCREATIC TRYPSIN INHIBITOR Authors: Zhang, W, Nielsen, C.B, Hansen, P.E. Deposit date: 2003-12-17 Release date: 2004-01-29 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: NMR Solution Structures of Modified and Truncated Bovine Pancreatic Trypsin Inhibitor Proteins (3-58 Bpti'S) To be Published
1UUA	Solution structure of a truncated bovine pancreatic trypsin inhibitor, 3-58 BPTI. Descriptor: BOVINE PANCREATIC TRYPSIN INHIBITOR Authors: Zhang, W, Nielsen, C.B, Hansen, P.E. Deposit date: 2003-12-17 Release date: 2004-01-29 Last modified: 2018-01-17 Method: SOLUTION NMR Cite: NMR Solution Structures of Modifies and Truncated Bovine Pancreatic Trypsin Inhibitor Proteins (3-58 Bpti'S) To be Published
4Z6A	Crystal Structure of a FVIIa-Trypsin Chimera (YT) in Complex with Soluble Tissue Factor Descriptor: CALCIUM ION, CITRIC ACID, Coagulation factor VII, ... Authors: Sorensen, A.B, Svensson, L.A, Gandhi, P.S. Deposit date: 2015-04-04 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity. J.Biol.Chem., 291, 2016
4SGB	STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEINASE B AND POLYPEPTIDE CHYMOTRYPSIN INHIBITOR-1 FROM RUSSET BURBANK POTATO TUBERS AT 2.1 ANGSTROMS RESOLUTION Descriptor: CALCIUM ION, POTATO INHIBITOR, PCI-1, ... Authors: James, M, Greenblatt, H. Deposit date: 1989-09-21 Release date: 1990-07-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 A resolution. J.Mol.Biol., 205, 1989
2PTN	ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY Descriptor: CALCIUM ION, TRYPSIN Authors: Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R. Deposit date: 1981-10-26 Release date: 1982-03-04 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.55 Å) Cite: On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography Acta Crystallogr.,Sect.B, 38, 1982

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