8JQW

Crystal structure of V30I mutated human transthyretin

Summary for 8JQW

• Entry DOI: 10.2210/pdb8jqw/pdb
• Descriptor: Transthyretin, MAGNESIUM ION (3 entities in total)
• Functional Keywords: thyroid hormone-binding protein, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 29956.09

Authors

Mizuguchi, M.,Yamada, S.,Obita, T. (deposition date: 2023-06-15, release date: 2024-04-17)

• Primary citation: Mizuguchi, M.,Obita, T.,Yamada, S.,Nabeshima, Y.; Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis.; Febs J., 2024; PubMed: 38273457; DOI: 10.1111/febs.17070

Experimental method

X-RAY DIFFRACTION (1.8 Å)