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6ZAY
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BU of 6zay by Molmil
Crystal structure of Atg16L in complex with GDP-bound Rab33B
Descriptor: 1,2-ETHANEDIOL, Autophagy-related protein 16-1, DI(HYDROXYETHYL)ETHER, ...
Authors:Pantoom, S, Wu, Y.W.
Deposit date:2020-06-06
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.
Autophagy, 17, 2021
7EA7
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BU of 7ea7 by Molmil
crystal structure of NAP1 LIR in complex with GABARAP
Descriptor: Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif
Authors:Fu, T, Pan, L.
Deposit date:2021-03-06
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
6Y09
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BU of 6y09 by Molmil
Crystal structure of Atg16L in complex with GTP-bound Rab33B (Q92L)
Descriptor: 1,2-ETHANEDIOL, Autophagy-related protein 16-1, DI(HYDROXYETHYL)ETHER, ...
Authors:Pantoom, S, Wu, Y.W.
Deposit date:2020-02-07
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.
Autophagy, 17, 2021
2AZE
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BU of 2aze by Molmil
Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Descriptor: Retinoblastoma-associated protein, Transcription factor Dp-1, Transcription factor E2F1
Authors:Rubin, S.M, Gall, A.L, Zheng, N, Pavletich, N.P.
Deposit date:2005-09-10
Release date:2006-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
Cell(Cambridge,Mass.), 123, 2005
3POM
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BU of 3pom by Molmil
Crystal Structure of the Unliganded Retinoblastoma Protein Pocket Domain
Descriptor: Retinoblastoma-associated protein
Authors:Balog, E.R.M, Burke, J.R, Rubin, S.M.
Deposit date:2010-11-23
Release date:2011-04-27
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the unliganded retinoblastoma protein pocket domain.
Proteins, 79, 2011
5XUY
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BU of 5xuy by Molmil
Crystal structure of ATG101-ATG13HORMA
Descriptor: Autophagy-related protein 101, Autophagy-related protein 13
Authors:Kim, B.-W, Song, H.K.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
Autophagy, 14, 2018
5XV3
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BU of 5xv3 by Molmil
Crystal structure of ATG101-ATG13HORMA
Descriptor: Autophagy-related protein 101, Autophagy-related protein 13, DI(HYDROXYETHYL)ETHER
Authors:Kim, B.-W, Song, H.K.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
Autophagy, 14, 2018
5XV4
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BU of 5xv4 by Molmil
Crystal structure of ATG101-ATG13HORMA
Descriptor: Autophagy-related protein 101, Autophagy-related protein 13
Authors:Kim, B.-W, Song, H.K.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
Autophagy, 14, 2018
5XV6
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BU of 5xv6 by Molmil
Crystal structure of ATG101-ATG13HORMA
Descriptor: Autophagy-related protein 101, Autophagy-related protein 13
Authors:Kim, B.-W, Song, H.K.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.455 Å)
Cite:The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
Autophagy, 14, 2018
1RKD
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BU of 1rkd by Molmil
E. COLI RIBOKINASE COMPLEXED WITH RIBOSE AND ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, RIBOKINASE, ...
Authors:Sigrell, J.A, Cameron, A.D, Jones, T.A, Mowbray, S.L.
Deposit date:1997-11-29
Release date:1998-03-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 A resolution: insights into a new family of kinase structures.
Structure, 6, 1998
1RKS
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BU of 1rks by Molmil
E. COLI RIBOKINASE IN COMPLEX WITH D-RIBOSE
Descriptor: PHOSPHATE ION, PROTEIN (RIBOKINASE), alpha-D-ribofuranose
Authors:Sigrell, J.A, Cameron, A.D, Mowbray, S.L.
Deposit date:1999-05-17
Release date:1999-08-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Induced fit on sugar binding activates ribokinase.
J.Mol.Biol., 290, 1999
4ELJ
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BU of 4elj by Molmil
Crystal structure of the inactive retinoblastoma protein phosphorylated at T373
Descriptor: Retinoblastoma-associated protein
Authors:Burke, J.R, Rubin, S.M.
Deposit date:2012-04-10
Release date:2012-05-23
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control.
Genes Dev., 26, 2012
4ELL
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BU of 4ell by Molmil
Structure of the inactive retinoblastoma protein pocket domain
Descriptor: Retinoblastoma-associated protein
Authors:Burke, J.R, Rubin, S.M.
Deposit date:2012-04-10
Release date:2012-05-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control.
Genes Dev., 26, 2012
2R7G
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BU of 2r7g by Molmil
Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain
Descriptor: Early E1A 32 kDa protein, Retinoblastoma-associated protein, SULFATE ION
Authors:Liu, X, Marmorstein, R.
Deposit date:2007-09-07
Release date:2007-10-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.671 Å)
Cite:Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor
Genes Dev., 21, 2007
2QDJ
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BU of 2qdj by Molmil
Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
Descriptor: Retinoblastoma-associated protein
Authors:Hassler, M, Mittnacht, S, Pearl, L.H.
Deposit date:2007-06-21
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
5Z9S
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BU of 5z9s by Molmil
Functional and Structural Characterization of a beta-Glucosidase Involved in Saponin Metabolism from Intestinal Bacteria
Descriptor: Glycosyl hydrolase family 3 protein, beta-D-glucopyranose
Authors:Yan, S, Wei, P.C, Li, J.R.
Deposit date:2018-02-05
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional and structural characterization of a beta-glucosidase involved in saponin metabolism from intestinal bacteria.
Biochem. Biophys. Res. Commun., 496, 2018
7O3V
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BU of 7o3v by Molmil
Stalk complex structure (TrwJ/VirB5-TrwI/VirB6) from the fully-assembled R388 type IV secretion system determined by cryo-EM.
Descriptor: TrwI protein, TrwJ protein
Authors:Mace, K, Vadakkepat, A.K, Lukoyanova, N, Waksman, G.
Deposit date:2021-04-03
Release date:2022-06-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of a type IV secretion system.
Nature, 607, 2022
7O41
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BU of 7o41 by Molmil
Hexameric composite model of the Inner Membrane Complex (IMC) with the Arches from the fully-assembled R388 type IV secretion system determined by cryo-EM.
Descriptor: TrwG protein, TrwK protein, TrwM protein
Authors:Mace, K, Vadakkepat, A.K, Lukoyanova, N, Waksman, G.
Deposit date:2021-04-04
Release date:2022-06-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Cryo-EM structure of a type IV secretion system.
Nature, 607, 2022
7OIU
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BU of 7oiu by Molmil
Inner Membrane Complex (IMC) protomer structure (TrwM/VirB3, TrwK/VirB4, TrwG/VirB8tails) from the fully-assembled R388 type IV secretion system determined by cryo-EM.
Descriptor: TrwG protein, TrwK protein, TrwM protein
Authors:Mace, K, Vadakkepat, A.K, Lukoyanova, N, Waksman, G.
Deposit date:2021-05-12
Release date:2022-06-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of a type IV secretion system.
Nature, 607, 2022
7Q1V
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BU of 7q1v by Molmil
Arches protomer (trimer of TrwG/VirB8peri) structure from the fully-assembled R388 type IV secretion system determined by cryo-EM.
Descriptor: TrwG protein
Authors:Mace, K, Vadakkepat, A.K, Lukoyanova, N, Waksman, G.
Deposit date:2021-10-21
Release date:2022-06-22
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (6.18 Å)
Cite:Cryo-EM structure of a type IV secretion system.
Nature, 607, 2022
6NY0
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BU of 6ny0 by Molmil
Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-(4-{3-[4-(6-carboxy-1H-benzimidazol-2-yl)phenoxy]-2-hydroxypropoxy}phenyl)-1H-benzimidazole-5-carboxylic acid, Dihydrofolate reductase type 2, ...
Authors:Yachnin, B.J, Berghuis, A.M.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues.
Acs Omega, 4, 2019
6NXZ
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BU of 6nxz by Molmil
Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-[4-[(2~{R})-4-[4-(6-carboxy-1~{H}-benzimidazol-2-yl)phenoxy]-2-oxidanyl-butoxy]phenyl]-1~{H}-benzimidazole-5-carboxylic acid, Dihydrofolate reductase type 2, ...
Authors:Yachnin, B.J, Berghuis, A.M.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues.
Acs Omega, 4, 2019
3C5J
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BU of 3c5j by Molmil
Crystal structure of HLA DR52c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Elongation factor 1-alpha 2, HLA class II histocompatibility antigen, ...
Authors:Dai, S, Kappler, J.W.
Deposit date:2008-01-31
Release date:2008-08-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Proc.Natl.Acad.Sci.USA, 105, 2008
5EEQ
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BU of 5eeq by Molmil
Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor
Descriptor: Bicyclic Peptide Inhibitor, Growth factor receptor-bound protein 7, PHOSPHATE ION
Authors:Ambaye, N.D, Watson, G.M, Wilce, M.C.J, Wilce, G.M.
Deposit date:2015-10-23
Release date:2016-06-15
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
5EEL
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BU of 5eel by Molmil
Grb7 SH2 with bicyclic peptide inhibitor
Descriptor: Bicyclic Peptide Inhibitor, FORMIC ACID, Growth factor receptor-bound protein 7, ...
Authors:Watson, G.M, Gunzburg, M.J, Wilce, M.C.J, Wilce, J.A.
Deposit date:2015-10-23
Release date:2016-06-15
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016

224931

數據於2024-09-11公開中

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