Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain

Summary for 2R7G

DescriptorRetinoblastoma-associated protein, Early E1A 32 kDa protein, SULFATE ION, ... (4 entities in total)
Functional Keywordsretinoblastoma protein, e1a, e2f displacement, transcription repressor, cell cycle
Biological sourceHomo sapiens (human)
Cellular locationNucleus  P06400
Host nucleus  P03255
Total number of polymer chains5
Total molecular weight85243.78
Liu, X.,Marmorstein, R. (deposition date: 2007-09-07, release date: 2007-10-02, Last modification date: 2017-10-25)
Primary citation
Liu, X.,Marmorstein, R.
Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor
Genes Dev., 21:2711-2716, 2007
PubMed: 17974914 (PDB entries with the same primary citation)
DOI: 10.1101/gad.1590607
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21870.6%5.9%10.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2r7g
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Molmil generated image of 2r7g
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Molmil generated image of 2r7g
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