2R7G

Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain

Summary for 2R7G

DescriptorRetinoblastoma-associated protein, Early E1A 32 kDa protein, SULFATE ION, ... (4 entities in total)
Functional Keywordsretinoblastoma protein, e1a, e2f displacement, transcription repressor, cell cycle
Biological sourceHomo sapiens (human)
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Cellular locationNucleus  P06400
Host nucleus  P03255
Total number of polymer chains5
Total molecular weight85243.78
Authors
Liu, X.,Marmorstein, R. (deposition date: 2007-09-07, release date: 2007-10-02, Last modification date: 2017-10-25)
Primary citation
Liu, X.,Marmorstein, R.
Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor
Genes Dev., 21:2711-2716, 2007
PubMed: 17974914 (PDB entries with the same primary citation)
DOI: 10.1101/gad.1590607
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.671 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21870.6%5.9%10.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2r7g
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Molmil generated image of 2r7g
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Molmil generated image of 2r7g
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