2R7G

Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0051726	biological_process	regulation of cell cycle
C	0005634	cellular_component	nucleus
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SO4 A 902

Chain	Residue
A	ASN406
C	LYS574
C	HOH1076
A	CYS407
A	THR408
A	ASN472
A	PHE473
A	SER474
A	HOH1001
A	HOH1009
A	HOH1087

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SO4 C 901

Chain	Residue
A	LYS574
A	HOH1060
C	ASN406
C	CYS407
C	THR408
C	ASN472
C	PHE473
C	SER474
C	HOH1003
C	HOH1011
C	HOH1088

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine; by CDK2 => ECO:0000269|PubMed:10499802

Chain	Residue	Details
A	SER567
C	SER567

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P13405

Chain	Residue	Details
A	LEU669
C	LEU669

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine; by CHEK2 and CHEK1 => ECO:0000269|PubMed:17380128, ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	HIS673
C	HIS673

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site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	GLN685
A	SER780
C	GLN685
C	SER780

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