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7OIU

Inner Membrane Complex (IMC) protomer structure (TrwM/VirB3, TrwK/VirB4, TrwG/VirB8tails) from the fully-assembled R388 type IV secretion system determined by cryo-EM.

Summary for 7OIU
Entry DOI10.2210/pdb7oiu/pdb
EMDB information12933
DescriptorTrwM protein, TrwK protein, TrwG protein (3 entities in total)
Functional Keywordstype iv secretion system, type 4 secretion system, t4ss, imc, inner membrane complex, inner membrane, arches, periplasmic, r388 plasmid, conjugation, bacterial secretion, secretion, secretion system, protein complex, virb3, virb4, virb8, trwm, trwk, trwg, membrane protein
Biological sourceEscherichia coli
More
Total number of polymer chains6
Total formula weight277232.43
Authors
Mace, K.,Vadakkepat, A.K.,Lukoyanova, N.,Waksman, G. (deposition date: 2021-05-12, release date: 2022-06-22, Last modification date: 2022-07-20)
Primary citationMace, K.,Vadakkepat, A.K.,Redzej, A.,Lukoyanova, N.,Oomen, C.,Braun, N.,Ukleja, M.,Lu, F.,Costa, T.R.D.,Orlova, E.V.,Baker, D.,Cong, Q.,Waksman, G.
Cryo-EM structure of a type IV secretion system.
Nature, 607:191-196, 2022
Cited by
PubMed: 35732732
DOI: 10.1038/s41586-022-04859-y
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.7 Å)
Structure validation

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