3ZKB
| CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPNP | Descriptor: | DNA GYRASE SUBUNIT B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Agrawal, A, Roue, M, Spitzfaden, C, Petrella, S, Aubry, A, Volker, C, Mossakowska, D, Hann, M, Bax, B, Mayer, C. | Deposit date: | 2013-01-22 | Release date: | 2013-09-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion. Biochem.J., 456, 2013
|
|
1GCB
| GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL) | Descriptor: | GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ... | Authors: | Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C. | Deposit date: | 1995-07-18 | Release date: | 1995-10-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science, 269, 1995
|
|
3BV0
| |
4RPI
| Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase from Mycobacterium tuberculosis | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, nicotinate-nucleotide adenylyltransferase | Authors: | Rodionova, I, Zuccola, H, Sorci, L, Aleshin, A.E, Kazanov, M, Sergienko, E, Rubin, E, Locher, C, Osterman, A. | Deposit date: | 2014-10-30 | Release date: | 2015-01-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.417 Å) | Cite: | Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery. J. Biol. Chem., 290, 2015
|
|
4FEH
| |
4FF6
| Mycobacterium tuberculosis DprE1 in complex with CT325 - monoclinic crystal form | Descriptor: | 3-(hydroxyamino)-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ... | Authors: | Batt, S.M, Besra, G.S, Futterer, K. | Deposit date: | 2012-05-31 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4CGE
| |
4IF7
| Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide | Descriptor: | (2S)-2-amino-4-(methyldisulfanyl)butanoic acid, COBALT (II) ION, Methionine aminopeptidase 2 | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-14 | Release date: | 2013-12-18 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
|
|
4IDY
| Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide | Descriptor: | 2-HYDROXYETHYL DISULFIDE, Methionine aminopeptidase 2, POTASSIUM ION | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-13 | Release date: | 2013-12-18 | Last modified: | 2015-02-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
|
|
4FFA
| Sulfatase from Mycobacterium tuberculosis | Descriptor: | NITRATE ION, Rv3406 alkyl sulfatase | Authors: | Sogi, K.M, Gartner, Z.J, Breidenbach, M.A, Bertozzi, C.R. | Deposit date: | 2012-05-31 | Release date: | 2013-06-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging. Plos One, 8, 2013
|
|
4FDN
| |
4FDP
| |
4FDO
| Mycobacterium tuberculosis DprE1 in complex with CT319 | Descriptor: | 3-nitro-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, FLAVIN-ADENINE DINUCLEOTIDE, oxidoreductase DprE1 | Authors: | Batt, S.M, Besra, G.S, Futterer, K. | Deposit date: | 2012-05-29 | Release date: | 2012-07-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3CXV
| |
2VZW
| X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosis | Descriptor: | ACETATE ION, OXYGEN MOLECULE, PROBABLE HISTIDINE KINASE RESPONSE REGULATOR, ... | Authors: | Podust, L.M, Ioanoviciu, A, Ortiz de Montellano, P.R. | Deposit date: | 2008-08-06 | Release date: | 2009-03-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | 2.3 A X-Ray Structure of the Heme-Bound Gaf Domain of Sensory Histidine Kinase Dost of Mycobacterium Tuberculosis. Biochemistry, 47, 2008
|
|
3QUO
| Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with ATP and fosfomycin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, FOSFOMYCIN, FomA protein | Authors: | Pakhomova, S, Bartlett, S.G, Doerner, P.A, Newcomer, M.E. | Deposit date: | 2011-02-24 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA. Biochemistry, 50, 2011
|
|
4Q6U
| |
2WM5
| X-ray structure of the substrate-free Mycobacterium tuberculosis cytochrome P450 CYP124 | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 124 | Authors: | Johnston, J.B, Kells, P.M, Podust, L.M, Ortiz de Montellano, P.R. | Deposit date: | 2009-06-30 | Release date: | 2009-10-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A., 106, 2009
|
|
2WM4
| X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP124 in complex with phytanic acid | Descriptor: | (3R,7S,11S)-3,7,11,15-tetramethylhexadecanoic acid, CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Johnston, J.B, Kells, P.M, Podust, L.M, Ortiz de Montellano, P.R. | Deposit date: | 2009-06-30 | Release date: | 2009-10-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A., 106, 2009
|
|
2YW6
| Structural studies of N terminal deletion mutant of Dps from Mycobacterium smegmatis | Descriptor: | DNA protection during starvation protein | Authors: | Roy, S, Saraswathi, R, Gupta, S, Sekar, K, Chatterji, D, Vijayan, M. | Deposit date: | 2007-04-19 | Release date: | 2007-07-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Role of N and C-terminal Tails in DNA Binding and Assembly in Dps: Structural Studies of Mycobacterium smegmatis Dps Deletion Mutants J.Mol.Biol., 370, 2007
|
|
2ZW4
| |
1D17
| DNA-NOGALAMYCIN INTERACTIONS | Descriptor: | DNA (5'-D(*(5CM)P*GP*TP*AP*(5CM)P*G)-3'), NOGALAMYCIN | Authors: | Egli, M, Williams, L.D, Frederick, C.A, Rich, A. | Deposit date: | 1990-08-08 | Release date: | 1991-07-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | DNA-nogalamycin interactions. Biochemistry, 30, 1991
|
|
2ZW5
| |
3UOF
| Mycobacterium tuberculosis bacterioferritin, BfrA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterioferritin, FE (III) ION, ... | Authors: | McMath, L.M, Goulding, C.W, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2011-11-16 | Release date: | 2012-11-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.902 Å) | Cite: | Mycobacterium tuberculosis bacterioferritin, BfrA To be Published
|
|
7CU9
| Crystal structure of the soluble domain of TiME protein from Mycobacterium smegmatis | Descriptor: | GLYCEROL, MAGNESIUM ION, Tube-forming protein in Mycobacterial Envelpe, ... | Authors: | Gong, W, Cai, X, Liu, L, Wen, C. | Deposit date: | 2020-08-21 | Release date: | 2021-08-25 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Identification and architecture of a putative secretion tube across mycobacterial outer envelope. Sci Adv, 7, 2021
|
|