PDB: 10938 resultsInfo pagesStatus searchChemie searchBIRD

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8F30	LSD1-CoREST in complex with AW2, long soaking Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-{5-[3-([1,1'-biphenyl]-4-yl)propanoyl]-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl}-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) Authors: Caroli, J, Mattevi, A. Deposit date: 2022-11-09 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
8F2Z	LSD1-CoREST in complex with AW2, short soaking Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,13R)-3-([1,1'-biphenyl]-4-yl)-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) Authors: Caroli, J, Mattevi, A. Deposit date: 2022-11-09 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (3 Å) Cite: Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
8F28	Lysozyme Structures from Single-Entity Crystallization Method NanoAC Descriptor: ACETATE ION, CHLORIDE ION, Lysozyme C, ... Authors: Yang, R, Sankaran, B, Ogbonna, E, Wang, G. Deposit date: 2022-11-07 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.2 Å) Cite: A Single-Entity Method for Actively Controlled Nucleation and High-Quality Protein Crystal Synthesis. Anal.Chem., 95, 2023
8F1G	Crystal structure of human WDR5 in complex with compound WM662 Descriptor: (2S)-2-({(2S)-3-(3'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-1-[(1H-tetrazol-5-yl)amino]propan-2-yl}oxy)propanoic acid, GLYCEROL, SULFATE ION, ... Authors: Liu, H. Deposit date: 2022-11-05 Release date: 2023-01-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. Acs Chem.Biol., 18, 2023
8EW1	Structure of Bacple_01703-E145L Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ... Authors: Ulaganathan, T, Cygler, M. Deposit date: 2022-10-21 Release date: 2023-05-10 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations Biorxiv, 2023
8EVJ	CX3CR1 nucleosome bound PU.1 and C/EBPa Descriptor: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Guan, R, Bai, Y, Lian, T. Deposit date: 2022-10-20 Release date: 2023-11-01 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
8EVI	CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations Descriptor: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Lian, T, Guan, R, Bai, Y. Deposit date: 2022-10-20 Release date: 2023-11-01 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.64 Å) Cite: Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
8EVH	CX3CR1 nucleosome and wild type PU.1 complex Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Lian, T, Guan, R, Bai, Y. Deposit date: 2022-10-20 Release date: 2023-11-01 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
8EVG	162bp CX3CR1 nucleosome (further classified with better nucleosome end) Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Tengfei, L, Ruifang, G, Yawen, B. Deposit date: 2022-10-20 Release date: 2023-11-01 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: Structural basis of cooperative targeting of the CX3CR1 nucleosome To Be Published
8EUJ	Class2 of the INO80-Nucleosome complex Descriptor: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. Deposit date: 2022-10-18 Release date: 2023-07-12 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
8EUE	Class1 of the INO80-Nucleosome complex Descriptor: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. Deposit date: 2022-10-18 Release date: 2023-07-12 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (3.48 Å) Cite: Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
8EU2	Class3 of the INO80-Hexasome complex Descriptor: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. Deposit date: 2022-10-18 Release date: 2023-07-12 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
8ETV	Class2 of the INO80-Hexasome complex Descriptor: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. Deposit date: 2022-10-17 Release date: 2023-07-12 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
8ETT	Class1 of the INO80-Hexasome complex Descriptor: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. Deposit date: 2022-10-17 Release date: 2023-07-12 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (6.68 Å) Cite: Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
8ETB	the crystal structure of a rationally designed zinc sensor based on maltose binding protein - Zn binding conformation Descriptor: ACETATE ION, ZINC ION, Zinc Sensor protein Authors: Zhao, Z, Zhou, M, Zemerov, S.D, Marmorstein, R, Dmochowski, I.J. Deposit date: 2022-10-16 Release date: 2023-03-22 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Rational design of a genetically encoded NMR zinc sensor. Chem Sci, 14, 2023
8ESX	HIV protease in complex with benzoxaborolone analog of darunavir Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Windsor, I.W, Graham, B.J, Raines, R.T. Deposit date: 2022-10-15 Release date: 2023-02-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability. Acs Med.Chem.Lett., 14, 2023
8ESC	Structure of the Yeast NuA4 Histone Acetyltransferase Complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... Authors: Patel, A.B, Zukin, S.A, Nogales, E. Deposit date: 2022-10-13 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure and flexibility of the yeast NuA4 histone acetyltransferase complex. Elife, 11, 2022
8EPV	2.2 A crystal structure of the lipocalin cat allergen Fel d 7 Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Fel d 7 allergen, ... Authors: Min, J, Pedersen, L.C, Geoffrey, M.A. Deposit date: 2022-10-06 Release date: 2023-04-05 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7. Front Allergy, 4, 2023
8EP4	Structure of Bacple_01703 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ... Authors: Ulaganathan, T, Cygler, M. Deposit date: 2022-10-05 Release date: 2022-11-09 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.94 Å) Cite: The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations Biorxiv, 2023
8EMI	Crystal structure of a HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.57301509 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMG	Crystal structure of a HLA-B*35:01-NP7 epitope from 2002 H2N1 influenza strain Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.83001268 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8ELH	Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANQF from SARS-CoV-2 virus Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... Authors: Murdolo, L.D, Gras, S. Deposit date: 2022-09-24 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature, 620, 2023
8ELG	Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANAF from OC43 virus Descriptor: ACETATE ION, Beta-2-microglobulin, NQK-OC43 peptide, ... Authors: Murdolo, L.D, Gras, S. Deposit date: 2022-09-24 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.65 Å) Cite: A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature, 620, 2023
8EIM	Structure of ALAS with C-terminal truncation from S. cerevisiae Descriptor: 5-aminolevulinate synthase, mitochondrial, ACETATE ION, ... Authors: Tran, J.U, Brown, B.L. Deposit date: 2022-09-15 Release date: 2023-03-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The yeast ALA synthase C-terminus positively controls enzyme structure and function. Protein Sci., 32, 2023
8EHN	PRRSV-1 PLP2 domain Descriptor: ACETATE ION, Papain-like protease 2, ZINC ION Authors: Bailey-Elkin, B.A, Mark, B.L. Deposit date: 2022-09-14 Release date: 2023-12-06 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. Plos Pathog., 19, 2023

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