2HK4
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143D
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1EVO
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![BU of 1evo by Molmil](/molmil-images/mine/1evo) | NMR OBSERVATION OF A NOVEL C-TETRAD | Descriptor: | DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*T)-3') | Authors: | Patel, P.K, Bhavesh, N.S, Hosur, R.V. | Deposit date: | 2000-04-20 | Release date: | 2000-05-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR observation of a novel C-tetrad in the structure of the SV40 repeat sequence GGGCGG. Biochem.Biophys.Res.Commun., 270, 2000
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4DIH
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![BU of 4dih by Molmil](/molmil-images/mine/4dih) | X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of sodium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-01-31 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 40, 2012
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1RDE
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7W9N
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![BU of 7w9n by Molmil](/molmil-images/mine/7w9n) | THE STRUCTURE OF OBA33-OTA COMPLEX | Descriptor: | (2~{S})-2-[[(3~{R})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid, OTA DNA APTAMER (33-MER) | Authors: | Xu, G.H, Li, C.G. | Deposit date: | 2021-12-10 | Release date: | 2022-01-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Insights into the Mechanism of High-Affinity Binding of Ochratoxin A by a DNA Aptamer. J.Am.Chem.Soc., 144, 2022
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5O6B
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![BU of 5o6b by Molmil](/molmil-images/mine/5o6b) | Structure of ScPif1 in complex with GGGTTTT and ADP-AlF4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, DNA (5'-D(*GP*GP*GP*TP*TP*T)-3'), ... | Authors: | Lu, K.Y, Chen, W.F, Rety, S, Liu, N.N, Xu, X.G. | Deposit date: | 2017-06-06 | Release date: | 2017-12-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.029 Å) | Cite: | Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase. Nucleic Acids Res., 46, 2018
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1EEG
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![BU of 1eeg by Molmil](/molmil-images/mine/1eeg) | A(GGGG)A HEXAD PAIRING ALIGMENT FOR THE D(G-G-A-G-G-A-G) SEQUENCE | Descriptor: | DNA (5'-D(*GP*GP*AP*GP*GP*A)-3') | Authors: | Kettani, A, Gorin, A, Majumdar, A, Hermann, T, Skripkin, E, Zhao, H, Jones, R, Patel, D.J. | Deposit date: | 2000-01-31 | Release date: | 2000-04-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations. J.Mol.Biol., 297, 2000
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4WB3
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![BU of 4wb3 by Molmil](/molmil-images/mine/4wb3) | Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a-desArg complement anaphylatoxin | Descriptor: | ACETATE ION, CALCIUM ION, Complement C5, ... | Authors: | Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R. | Deposit date: | 2014-09-02 | Release date: | 2015-05-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer. Nat Commun, 6, 2015
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4WB2
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![BU of 4wb2 by Molmil](/molmil-images/mine/4wb2) | Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a complement anaphylatoxin | Descriptor: | ACETATE ION, CALCIUM ION, Complement C5, ... | Authors: | Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R. | Deposit date: | 2014-09-02 | Release date: | 2015-05-06 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer. Nat Commun, 6, 2015
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4LZ4
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![BU of 4lz4 by Molmil](/molmil-images/mine/4lz4) | X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 3 nucleobase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... | Authors: | Pica, A, Russo Krauss, I, Merlino, A, Sica, F. | Deposit date: | 2013-07-31 | Release date: | 2014-01-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer. Febs J., 280, 2013
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4LZ1
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![BU of 4lz1 by Molmil](/molmil-images/mine/4lz1) | X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 12 nucleobase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... | Authors: | Pica, A, Russo Krauss, I, Merlino, A, Sica, F. | Deposit date: | 2013-07-31 | Release date: | 2014-01-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer. Febs J., 280, 2013
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6E8T
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6E8U
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![BU of 6e8u by Molmil](/molmil-images/mine/6e8u) | Structure of the Mango-III (A10U) aptamer bound to TO1-Biotin | Descriptor: | 4-[(3-{2,16-dioxo-20-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Trachman, R.J, Ferre-D'Amare, A.R. | Deposit date: | 2018-07-31 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure and functional reselection of the Mango-III fluorogenic RNA aptamer. Nat. Chem. Biol., 15, 2019
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6E8S
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![BU of 6e8s by Molmil](/molmil-images/mine/6e8s) | Structure of the iMango-III aptamer bound to TO1-Biotin | Descriptor: | 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Trachman, R.J, Ferre-D'Amare, A.R. | Deposit date: | 2018-07-31 | Release date: | 2019-04-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure and functional reselection of the Mango-III fluorogenic RNA aptamer. Nat. Chem. Biol., 15, 2019
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1F3S
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![BU of 1f3s by Molmil](/molmil-images/mine/1f3s) | Solution Structure of DNA Sequence GGGTTCAGG Forms GGGG Tetrade and G(C-A) Triad. | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*TP*CP*AP*GP*G)-3') | Authors: | Kettani, A, Basu, G, Gorin, A, Majumdar, A, Skripkin, E, Patel, D.J. | Deposit date: | 2000-06-06 | Release date: | 2000-11-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A two-stranded template-based approach to G.(C-A) triad formation: designing novel structural elements into an existing DNA framework. J.Mol.Biol., 301, 2000
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8FI8
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1EU2
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1EVN
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![BU of 1evn by Molmil](/molmil-images/mine/1evn) | NMR OBSERVATION OF A-TETRAD | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*T)-3') | Authors: | Patel, P.K, Koti, A.S.R, Hosur, R.V. | Deposit date: | 2000-04-20 | Release date: | 2000-05-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR studies on truncated sequences of human telomeric DNA: observation of a novel A-tetrad. Nucleic Acids Res., 27, 1999
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1EU6
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1EVM
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![BU of 1evm by Molmil](/molmil-images/mine/1evm) | NMR OBSERVATION OF A-TETRAD | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*T)-3') | Authors: | Patel, P.K, Koti, A.S.R, Hosur, R.V. | Deposit date: | 2000-04-20 | Release date: | 2000-05-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR studies on truncated sequences of human telomeric DNA: observation of a novel A-tetrad. Nucleic Acids Res., 27, 1999
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6K84
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![BU of 6k84 by Molmil](/molmil-images/mine/6k84) | Structure of anti-prion RNA aptamer | Descriptor: | RNA (25-MER) | Authors: | Mashima, T, Lee, J.H, Hayashi, T, Nagata, T, Kinoshita, M, Katahira, M. | Deposit date: | 2019-06-11 | Release date: | 2020-04-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Development and structural determination of an anti-PrPCaptamer that blocks pathological conformational conversion of prion protein. Sci Rep, 10, 2020
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8EYW
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![BU of 8eyw by Molmil](/molmil-images/mine/8eyw) | Beetroot dimer bound to ThT | Descriptor: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, POTASSIUM ION, RNA (49-MER) | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | Deposit date: | 2022-10-28 | Release date: | 2023-05-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture. Nat Commun, 14, 2023
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8EYU
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![BU of 8eyu by Molmil](/molmil-images/mine/8eyu) | Structure of Beetroot dimer bound to DFAME | Descriptor: | POTASSIUM ION, RNA (49-MER), methyl (2E)-3-{(4Z)-4-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl}prop-2-enoate | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | Deposit date: | 2022-10-28 | Release date: | 2023-05-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture. Nat Commun, 14, 2023
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8EYV
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![BU of 8eyv by Molmil](/molmil-images/mine/8eyv) | Structure of Beetroot dimer bound to DFHO | Descriptor: | (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, POTASSIUM ION, RNA (45-MER) | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | Deposit date: | 2022-10-28 | Release date: | 2023-05-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture. Nat Commun, 14, 2023
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