Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1MX0
DownloadVisualize
BU of 1mx0 by Molmil
Structure of topoisomerase subunit
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION, ...
Authors:Corbett, K.D, Berger, J.M.
Deposit date:2002-10-01
Release date:2003-01-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
Embo J., 22, 2003
1PVG
DownloadVisualize
BU of 1pvg by Molmil
Crystal Structure of the ATPase region of Saccharomyces Cerevisiae topoisomerase II
Descriptor: DNA topoisomerase II, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Classen, S, Olland, S, Berger, J.M.
Deposit date:2003-06-27
Release date:2003-08-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Proc.Natl.Acad.Sci.USA, 100, 2003
1QZR
DownloadVisualize
BU of 1qzr by Molmil
CRYSTAL STRUCTURE OF THE ATPASE REGION OF SACCHAROMYCES CEREVISIAE TOPOISOMERASE II BOUND TO ICRF-187 (DEXRAZOXANE)
Descriptor: (S)-4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-2,6-PIPERAZINEDIONE, DNA topoisomerase II, MAGNESIUM ION, ...
Authors:Classen, S, Olland, S, Berger, J.M.
Deposit date:2003-09-17
Release date:2003-09-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Proc.Natl.Acad.Sci.USA, 100, 2003
1R62
DownloadVisualize
BU of 1r62 by Molmil
Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)
Descriptor: Nitrogen regulation protein NR(II)
Authors:Song, Y, Peisach, D, Pioszak, A.A, Xu, Z, Ninfa, A.J.
Deposit date:2003-10-14
Release date:2004-06-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the C-terminal Domain of the Two-Component System Transmitter Protein Nitrogen Regulator II (NRII; NtrB), Regulator of Nitrogen Assimilation in Escherichia coli.
Biochemistry, 43, 2004
1S14
DownloadVisualize
BU of 1s14 by Molmil
Crystal structure of Escherichia coli Topoisomerase IV ParE 24kDa subunit
Descriptor: NOVOBIOCIN, Topoisomerase IV subunit B
Authors:Wei, Y, Gross, C.H.
Deposit date:2004-01-05
Release date:2004-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyrase.
Antimicrob.Agents Chemother., 48, 2004
1S16
DownloadVisualize
BU of 1s16 by Molmil
Crystal Structure of E. coli Topoisomerase IV ParE 43kDa subunit complexed with ADPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ...
Authors:Wei, Y, Gross, C.H.
Deposit date:2004-01-05
Release date:2004-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyrase.
Antimicrob.Agents Chemother., 48, 2004
1TH8
DownloadVisualize
BU of 1th8 by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form II
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigian, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1THN
DownloadVisualize
BU of 1thn by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1TID
DownloadVisualize
BU of 1tid by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-02
Release date:2004-06-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1TIL
DownloadVisualize
BU of 1til by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA:Poised for phosphorylation complex with ATP, crystal form II
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-02
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1US7
DownloadVisualize
BU of 1us7 by Molmil
Complex of Hsp90 and P50
Descriptor: HEAT SHOCK PROTEIN HSP82, HSP90 CO-CHAPERONE CDC37
Authors:Roe, S.M, Ali, M.M.U, Pearl, L.H.
Deposit date:2003-11-20
Release date:2004-01-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Mechanism of Hsp90 Regulation by the Protein Kinase-Specific Cochaperone p50(Cdc37)
Cell(Cambridge,Mass.), 116, 2004
1Y4S
DownloadVisualize
BU of 1y4s by Molmil
Conformation rearrangement of heat shock protein 90 upon ADP binding
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein htpG, MAGNESIUM ION
Authors:Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H.
Deposit date:2004-12-01
Release date:2005-04-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
1Y4U
DownloadVisualize
BU of 1y4u by Molmil
Conformation rearrangement of heat shock protein 90 upon ADP binding
Descriptor: Chaperone protein htpG
Authors:Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H.
Deposit date:2004-12-01
Release date:2005-04-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
1Y8N
DownloadVisualize
BU of 1y8n by Molmil
Crystal structure of the PDK3-L2 complex
Descriptor: DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, POTASSIUM ION, ...
Authors:Kato, M, Chuang, J.L, Wynn, R.M, Chuang, D.T.
Deposit date:2004-12-13
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.
Embo J., 24, 2005
1Y8O
DownloadVisualize
BU of 1y8o by Molmil
Crystal structure of the PDK3-L2 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, ...
Authors:Kato, M, Chuang, J.L, Wynn, R.M, Chuang, D.T.
Deposit date:2004-12-13
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.
Embo J., 24, 2005
1Y8P
DownloadVisualize
BU of 1y8p by Molmil
Crystal structure of the PDK3-L2 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, ...
Authors:Kato, M, Chuang, J.L, Wynn, R.M, Chuang, D.T.
Deposit date:2004-12-13
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.
Embo J., 24, 2005
1YS3
DownloadVisualize
BU of 1ys3 by Molmil
Crystal Structure of the ATP binding domain of PrrB from Mycobacterium Tuberculosis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Sensor-type histidine kinase prrB
Authors:Nowak, E, Panjikar, S, Tucker, P, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2005-02-07
Release date:2005-07-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of ATP binding domain of Hidtidine Kinase from MTB
To be Published
1YSR
DownloadVisualize
BU of 1ysr by Molmil
Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Sensor-type histidine kinase prrB
Authors:Nowak, E, Panjikar, S, Tucker, P, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2005-02-09
Release date:2005-07-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis
To be published
1Z59
DownloadVisualize
BU of 1z59 by Molmil
Topoisomerase VI-B, ADP-bound monomer form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Type II DNA topoisomerase VI subunit B
Authors:Corbett, K.D, Berger, J.M.
Deposit date:2005-03-17
Release date:2005-06-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI.
Structure, 13, 2005
1Z5A
DownloadVisualize
BU of 1z5a by Molmil
Topoisomerase VI-B, ADP-bound dimer form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Type II DNA topoisomerase VI subunit B
Authors:Corbett, K.D, Berger, J.M.
Deposit date:2005-03-17
Release date:2005-06-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI.
Structure, 13, 2005
1Z5B
DownloadVisualize
BU of 1z5b by Molmil
Topoisomerase VI-B, ADP AlF4- bound dimer form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ...
Authors:Corbett, K.D, Berger, J.M.
Deposit date:2005-03-17
Release date:2005-06-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI.
Structure, 13, 2005
1Z5C
DownloadVisualize
BU of 1z5c by Molmil
Topoisomerase VI-B, ADP Pi bound dimer form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Corbett, K.D, Berger, J.M.
Deposit date:2005-03-17
Release date:2005-06-14
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI.
Structure, 13, 2005
1ZW9
DownloadVisualize
BU of 1zw9 by Molmil
Yeast HSP82 in complex with the Novel HSP90 Inhibitor 8-(6-Bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)-adenine
Descriptor: 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE, HSP82
Authors:Immormino, R.M, Gewirth, D.T, Chiosis, G.
Deposit date:2005-06-03
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibitory Ligands Adopt Different Conformations When Bound to Hsp90 or GRP94: Implications for Paralog-specific Drug Design
To be Published
1ZWH
DownloadVisualize
BU of 1zwh by Molmil
Yeast Hsp82 in complex with the novel Hsp90 inhibitor Radester amine
Descriptor: 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE, ATP-dependent molecular chaperone HSP82
Authors:Immormino, R.M, Blagg, B.S, Gewirth, D.T.
Deposit date:2005-06-03
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Inhibitory Ligands Adopt Different Conformations When Bound to Hsp90 or GRP94: Implications for Paralog-specific Drug Design
To be Published
1ZXM
DownloadVisualize
BU of 1zxm by Molmil
Human Topo IIa ATPase/AMP-PNP
Descriptor: DNA topoisomerase II, alpha isozyme, MAGNESIUM ION, ...
Authors:Wei, H, Ruthenburg, A.J, Bechis, S.K, Verdine, G.L.
Deposit date:2005-06-08
Release date:2005-08-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase.
J.Biol.Chem., 280, 2005

227344

數據於2024-11-13公開中

PDB statisticsPDBj update infoContact PDBjnumon