3NE1
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3NFD
| Chronobacterium ammoniagenes ACPS-CoA complex | Descriptor: | COENZYME A, Phosphopantetheine protein transferase, Ppt1p | Authors: | Gokulan, K. | Deposit date: | 2010-06-10 | Release date: | 2011-01-05 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations. Acta Crystallogr.,Sect.D, 67, 2011
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3NE3
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3GWM
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3H7Q
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3HQJ
| Structure-function analysis of Mycobacterium tuberculosis acyl carrier protein synthase (AcpS). | Descriptor: | COENZYME A, Holo-[acyl-carrier-protein] synthase, MAGNESIUM ION | Authors: | Dym, O, Albeck, S, Peleg, Y, Schwarz, A, Shakked, Z, Burstein, Y, Zimhony, O, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2009-06-07 | Release date: | 2009-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis. J.Mol.Biol., 393, 2009
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3HYK
| 2.31 Angstrom resolution crystal structure of a holo-(acyl-carrier-protein) synthase from Bacillus anthracis str. Ames in complex with CoA (3',5'-ADP) | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, CHLORIDE ION, Holo-[acyl-carrier-protein] synthase, ... | Authors: | Halavaty, A.S, Minasov, G, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-06-22 | Release date: | 2009-06-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria. Acta Crystallogr.,Sect.D, 68, 2012
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2WDO
| Crystal structure of the S. coelicolor AcpS in complex with acetyl- CoA at 1.5 A | Descriptor: | ACETYL COENZYME *A, COENZYME A, GLYCEROL, ... | Authors: | Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T. | Deposit date: | 2009-03-25 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity. Biochemistry, 50, 2011
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2WAT
| Structure of the fungal type I FAS PPT domain in complex with CoA | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, CHLORIDE ION, COENZYME A, ... | Authors: | Johansson, P, Mulincacci, B, Koestler, C, Grininger, M. | Deposit date: | 2009-02-15 | Release date: | 2009-08-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Multimeric Options for the Auto-Activation of the Saccharomyces Cerevisiae Fas Type I Megasynthase. Structure, 17, 2009
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2WDS
| Crystal structure of the Streptomyces coelicolor H110A AcpS mutant in complex with cofactor CoA at 1.3 A | Descriptor: | COENZYME A, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, MAGNESIUM ION | Authors: | Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T. | Deposit date: | 2009-03-26 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity. Biochemistry, 50, 2011
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2WAS
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2WDY
| Crystal structure of the Streptomyces coelicolor D111A AcpS mutant in complex with cofactor CoA at 1.4 A | Descriptor: | COENZYME A, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, MAGNESIUM ION, ... | Authors: | Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T. | Deposit date: | 2009-03-27 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity. Biochemistry, 50, 2011
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4U89
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8GKF
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7B4R
| Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea | Descriptor: | COENZYME A, MANGANESE (II) ION, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, ... | Authors: | Maveyraud, L, Carivenc, C, Blanger, C, Mourey, L. | Deposit date: | 2020-12-02 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11, 2021
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7B4S
| Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and compound 153786 from the NCI Open Database | Descriptor: | 5-[(4-chlorophenyl)methyl]-6-[[2-(dimethylamino)ethylamino]methyl]-4-oxidanyl-1~{H}-pyrimidine-2-thione, COENZYME A, MANGANESE (II) ION, ... | Authors: | Maveyraud, L, Carivenc, C, Mourey, L. | Deposit date: | 2020-12-02 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11, 2021
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7N8L
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7N8M
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7N8E
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4QJK
| Crystal structure of M. tuberculosis phosphopantetheinyl transferase PptT | Descriptor: | COENZYME A, Phosphopantetheinyl transferase PptT, SULFATE ION | Authors: | Noel, J.P, Burkart, M.D, Vickery, C.R. | Deposit date: | 2014-06-04 | Release date: | 2014-07-16 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria. Acs Chem.Biol., 9, 2014
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4QJL
| Crystal structure of M. ulcerans phosphopantetheinyl transferase MuPPT | Descriptor: | COENZYME A, MAGNESIUM ION, Phosphopantetheinyl transferase, ... | Authors: | Noel, J.P, Burkart, M.D, Vickery, C.R. | Deposit date: | 2014-06-04 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria. Acs Chem.Biol., 9, 2014
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7ED1
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7ED0
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7ED2
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7BCZ
| Structure of the 4'-phosphopantetheinyl transferase PcpS from Pseudomonas aeruginosa | Descriptor: | 4'-phosphopantetheinyl transferase EntD, COENZYME A, MAGNESIUM ION, ... | Authors: | Carivenc, C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2020-12-21 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11, 2021
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