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1BE9
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BU of 1be9 by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
Descriptor: CRIPT, PSD-95
Authors:Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
Deposit date:1998-05-20
Release date:1998-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1D5G
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BU of 1d5g by Molmil
SOLUTION STRUCTURE OF THE PDZ2 DOMAIN FROM HUMAN PHOSPHATASE HPTP1E COMPLEXED WITH A PEPTIDE
Descriptor: HUMAN PHOSPHATASE HPTP1E, PEPTIDE FADSEADENEQVSAV
Authors:Kozlov, G, Gehring, K, Ekiel, I.
Deposit date:1999-10-07
Release date:2002-07-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions
J.Mol.Biol., 320, 2002
8OEP
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BU of 8oep by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
Descriptor: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C.
Deposit date:2023-03-11
Release date:2023-05-10
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Front Mol Biosci, 10, 2023
8YR7
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BU of 8yr7 by Molmil
Crystal structure of human dishevelled 2 (Dvl2) PDZ domain fused with WGEF internal peptide motif
Descriptor: Segment polarity protein dishevelled homolog DVL-2,Rho guanine nucleotide exchange factor 19
Authors:Omble, A, Mahajan, S, Kulkarni, K.A.
Deposit date:2024-03-20
Release date:2024-05-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
7MFW
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BU of 7mfw by Molmil
Drosophila melanogaster Canoe PDZ domain in complex with Echinoid C-terminal region
Descriptor: Canoe,Echinoid
Authors:Slep, K.C, Peifer, M, Byrnes, A.E.
Deposit date:2021-04-11
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis.
J.Cell Biol., 220, 2021
7E0B
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BU of 7e0b by Molmil
The crystal structure of sorting nexin 27 and PBM complex
Descriptor: PBM, Sorting nexin-27
Authors:Shang, G.J, Qi, J.X.
Deposit date:2021-01-27
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Proc.Natl.Acad.Sci.USA, 119, 2022
1G9O
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BU of 1g9o by Molmil
FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR
Descriptor: NHE-RF
Authors:Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A.
Deposit date:2000-11-26
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains.
J.Mol.Biol., 308, 2001
1GM1
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BU of 1gm1 by Molmil
Second PDZ Domain (PDZ2) of PTP-BL
Descriptor: PROTEIN TYROSINE PHOSPHATASE
Authors:Walma, T, Tessari, M, Aelen, J, Schepens, J, Hendriks, W, Vuister, G.W.
Deposit date:2001-09-06
Release date:2002-03-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL.
J. Mol. Biol., 316, 2002
4UU5
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BU of 4uu5 by Molmil
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE
Descriptor: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4WYU
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BU of 4wyu by Molmil
Crystal Structure of Scribble PDZ34 tandem in complex with its target peptide
Descriptor: IODIDE ION, Protein scribble homolog, peptide SER-TRP-PHE-GLN-THR-ASP-LEU
Authors:Ren, J.Q, Pei, H.H, Feng, W.
Deposit date:2014-11-18
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.
Biochem.J., 468, 2015
4WYT
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BU of 4wyt by Molmil
Crystal Structure of Scribble PDZ34 tandem at 2.6 Angstroms
Descriptor: CHLORIDE ION, Protein scribble homolog
Authors:Ren, J.Q, Feng, W.
Deposit date:2014-11-18
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.
Biochem.J., 468, 2015
6GBD
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BU of 6gbd by Molmil
Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain
Descriptor: PDZ3
Authors:Kock, G, Stoll, R.
Deposit date:2018-04-13
Release date:2018-12-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13.
J. Mol. Biol., 430, 2018
4R2Z
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BU of 4r2z by Molmil
Molecular Analysis of the PDZ4 Domain of Mouse PDZK1
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3
Authors:Birrane, G, Kocher, O, Krieger, M.
Deposit date:2014-08-13
Release date:2015-08-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Analysis of the PDZ4 domain from Mouse PDZK1
To be Published
6BXG
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BU of 6bxg by Molmil
1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide.
Descriptor: CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ...
Authors:Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-12-18
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide.
To Be Published
6HKS
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BU of 6hks by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
Descriptor: IODIDE ION, Protein E6, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Haouz, A, Caillet-Saguy, C.
Deposit date:2018-09-07
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1944108 Å)
Cite:Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
Sci Rep, 9, 2019
6EEY
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BU of 6eey by Molmil
Crystal structure of human Scribble PDZ4 R1110G Mutant
Descriptor: Protein scribble homolog
Authors:Janezic, E.M, Hsu, P, Hague, C.
Deposit date:2018-08-15
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.145 Å)
Cite:Scribble co-operatively binds multiple alpha1D-adrenergic receptor C-terminal PDZ ligands.
Sci Rep, 9, 2019
6IRE
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BU of 6ire by Molmil
Complex structure of INAD PDZ45 and NORPA CC-PBM
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, Inactivation-no-after-potential D protein
Authors:Ye, F, Li, J, Deng, X, Liu, W, Zhang, M.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
6EZI
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BU of 6ezi by Molmil
PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.
Descriptor: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2
Authors:Loew, C, Flayhan, A, Pieprzyk, J.
Deposit date:2017-11-15
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.503321 Å)
Cite:Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution.
Structure, 26, 2018
6ESP
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BU of 6esp by Molmil
Proteome-wide analysis of phospho-regulated PDZ domain interactions
Descriptor: Protein scribble homolog
Authors:Chi, N.C.
Deposit date:2017-10-24
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Proteome-wide analysis of phospho-regulated PDZ domain interactions.
Mol. Syst. Biol., 14, 2018
6MYE
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BU of 6mye by Molmil
Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)
Descriptor: FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ...
Authors:Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J.
Deposit date:2018-11-01
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
6MS1
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BU of 6ms1 by Molmil
Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC
Descriptor: 1,2-ETHANEDIOL, APC C-terminus peptide, Protein scribble homolog
Authors:How, J.Y, Kvansakul, M, Caria, S, Humbert, P.O.
Deposit date:2018-10-16
Release date:2019-02-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC.
FEBS Lett., 593, 2019
6MYF
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BU of 6myf by Molmil
Crystal structure of free human Scribble PDZ1 domain
Descriptor: Protein scribble homolog
Authors:Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J.
Deposit date:2018-11-01
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
6NID
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BU of 6nid by Molmil
Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain in complex with Neurexin-1 peptide
Descriptor: 1,2-ETHANEDIOL, Neurexin-1, Peripheral plasma membrane protein CASK
Authors:Sun, Y.J, Gakhar, L, Fuentes, E.J.
Deposit date:2018-12-27
Release date:2020-01-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:CASK PDZ domain specificity
To be published
6NH9
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BU of 6nh9 by Molmil
Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain
Descriptor: Peripheral plasma membrane protein CASK
Authors:Sun, Y.J, Gakhar, L, Fuentes, E.J.
Deposit date:2018-12-21
Release date:2019-12-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:CASK PDZ domain specificity
To be published
5ZYS
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BU of 5zys by Molmil
Structure of Nephrin/MAGI1 complex
Descriptor: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin
Authors:Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G.
Deposit date:2018-05-28
Release date:2019-01-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling.
J. Am. Soc. Nephrol., 29, 2018

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數據於2024-08-07公開中

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