8ZRW
 
 | | Structure of human ECHS1 in complex with Octanoyl-CoA | | Descriptor: | Enoyl-CoA hydratase, mitochondrial, MAGNESIUM ION, ... | | Authors: | Su, G, Xu, Y, Chen, B, Ju, K, Sun, X, Jin, Y, Liu, D, Chen, H, Zhang, S, Luan, X. | | Deposit date: | 2024-06-05 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.29 Å) | | Cite: | Structural and biochemical mechanism of short-chain enoyl-CoA hydratase (ECHS1) substrate recognition.
Commun Biol, 8, 2025
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2I8T
 | | GDP-mannose mannosyl hydrolase-calcium-GDP-mannose complex | | Descriptor: | CALCIUM ION, GDP-mannose mannosyl hydrolase, GLYCEROL, ... | | Authors: | Zou, Y, Li, C, Brunzelle, J.S, Nair, S.K. | | Deposit date: | 2006-09-03 | | Release date: | 2007-06-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme
Biochemistry, 46, 2007
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8ZEU
 | | CryoEM structure of GR2002-F(ab')2: TSLP complex | | Descriptor: | Fab fragment, light chain, Fab-H1A10 fragment, ... | | Authors: | Zhigang, L, Junjie, H. | | Deposit date: | 2024-05-07 | | Release date: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Preclinical development of GR2002, a novel anti-TSLP bispecific antibody with potent TSLP inhibitory effects
To Be Published
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2I9D
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2IAE
 | | Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme. | | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | Authors: | Cho, U.S, Xu, W. | | Deposit date: | 2006-09-07 | | Release date: | 2006-12-26 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
Nature, 445, 2007
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5JM8
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2IBN
 | | Crystal structure of Human myo-Inositol Oxygenase (MIOX) | | Descriptor: | (2S,3R,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXANONE, CYSTEINE, FE (III) ION, ... | | Authors: | Hallberg, B.M, Busam, R.D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Johansson, I, Karlberg, T, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Sagemark, J, Stenmark, P, Sundstrom, M, Uppenberg, J, Van Den Berg, S, Weigelt, J, Thorsell, A.G, Persson, C, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-09-11 | | Release date: | 2006-10-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and Biophysical Characterization of Human myo-Inositol Oxygenase
J.Biol.Chem., 283, 2008
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8ZMC
 | | Dengue 3 NS5 methyltransferase bound to S-Adenosyl-L-homocysteine and Herbacetin | | Descriptor: | Dengue 3 NS5 methyltransferase, GLYCEROL, Herbacetin, ... | | Authors: | Bhutkar, M, Verma, S, Tomar, S, Kumar, P. | | Deposit date: | 2024-05-23 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Dengue 3 NS5 methyltransferase bound to S-Adenosyl-L-homocysteine and Herbacetin
To Be Published
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8ZN0
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9B0N
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6KW6
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2I9W
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5JHV
 | | Apo form of influenza strain H1N1 polymerase acidic subunit N-terminal region crystallized with polyethylene glycol 8000 | | Descriptor: | MANGANESE (II) ION, Polymerase acidic protein | | Authors: | Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Hoshino, T. | | Deposit date: | 2016-04-21 | | Release date: | 2016-05-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.749 Å) | | Cite: | Influence of Precipitants on Molecular Arrangements and Space Groups of Protein Crystals
Cryst.Growth Des., 17, 2017
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8ZNU
 | | Catalytic antibody T99_C220A_dP95 | | Descriptor: | 1,2-ETHANEDIOL, CACODYLIC ACID, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Kobayashi, J, Yoshida, H, Tsuyuguchi, M, Kato, R. | | Deposit date: | 2024-05-28 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and biochemical differences between non-catalytic and catalytic antibodies.
Mabs, 17, 2025
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5JI6
 | | Potent, Reversible MetAP2 Inhibitors via FBDD | | Descriptor: | 4-(3-methylpyridin-4-yl)-6-(trifluoromethyl)-1H-indazole, MANGANESE (II) ION, Methionine aminopeptidase 2, ... | | Authors: | Dougan, D.R, Lawson, J.D. | | Deposit date: | 2016-04-21 | | Release date: | 2016-05-25 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 1.
Bioorg.Med.Chem.Lett., 26, 2016
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8ZNT
 | | Catalytic antibody T99_C220A | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Catalytic antibody T99_C220A, ... | | Authors: | Kobayashi, J, Yoshida, H, Tsuyuguchi, M, Kato, R. | | Deposit date: | 2024-05-28 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structural and biochemical differences between non-catalytic and catalytic antibodies.
Mabs, 17, 2025
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8ZRO
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8ZVY
 | | Alpha-Synuclein with H2a-H2b dimer complex structure. | | Descriptor: | CHLORIDE ION, Histone H2B 1.1,Histone H2A type 1, Isoform 1 of Alpha-synuclein | | Authors: | Padavattan, S, Jos, S, Kambaru, A. | | Deposit date: | 2024-06-12 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Structural and functional insights into the nuclear role of Parkinson's disease-associated alpha-synuclein as a histone chaperone.
Commun Biol, 8, 2025
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2HY1
 | | Crystal structure of Rv0805 | | Descriptor: | FE (III) ION, MANGANESE (II) ION, PHOSPHATE ION, ... | | Authors: | Shenoy, A.R, Capuder, M, Draskovic, P, Lamba, D, Visweswariah, S.S, Podobnik, M. | | Deposit date: | 2006-08-04 | | Release date: | 2006-12-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.932 Å) | | Cite: | Structural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis.
J.Mol.Biol., 365, 2007
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9AZM
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5JIE
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8ZMD
 | | Protease-activated receptor-2 (PAR2)/Gq complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Proteinase-activated receptor 2, ... | | Authors: | He, Y, Zhu, X. | | Deposit date: | 2024-05-23 | | Release date: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Protease-activated receptor-2 (PAR2)/Gq complex
To Be Published
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8ZVK
 | | Crystal structure of the GH5 domain from a processive endoglucanase of Acetivibrio alkalicellulosi | | Descriptor: | AaBgIC | | Authors: | Jia, M.X, Chen, Y.Y, Wang, J.H, Ma, Y.H, Ma, Q, Zhang, Y.H, Liu, W.D, Liu, K.Q. | | Deposit date: | 2024-06-11 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | His 70 of Acetivibrio alkalicellulosi Cel5A is important for efficient hydrolysis of short cellodextrins.
Amb Express, 15, 2025
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2HYW
 | | Human Annexin A2 with Calcium bound | | Descriptor: | Annexin A2, CALCIUM ION | | Authors: | Shao, C, Head, J.F, Seaton, B.A. | | Deposit date: | 2006-08-07 | | Release date: | 2006-09-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
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8ZW0
 | | Cryo-EM strcuture of Prostaglandin D2 Receptor DP1 activated by PGD2 | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Xu, J, Xu, Y, Wu, C, Xu, H.E. | | Deposit date: | 2024-06-12 | | Release date: | 2025-05-28 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1.
Proc.Natl.Acad.Sci.USA, 122, 2025
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