7R6Q
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![BU of 7r6q by Molmil](/molmil-images/mine/7r6q) | State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model | Descriptor: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-23 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7W6S
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![BU of 7w6s by Molmil](/molmil-images/mine/7w6s) | CryoEM structure of human KChIP2-Kv4.3 complex | Descriptor: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 2 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-12-02 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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7W6N
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![BU of 7w6n by Molmil](/molmil-images/mine/7w6n) | CryoEM structure of human KChIP1-Kv4.3 complex | Descriptor: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-12-02 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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7W6T
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![BU of 7w6t by Molmil](/molmil-images/mine/7w6t) | CryoEM structure of human KChIP1-Kv4.3-DPP6 complex | Descriptor: | Dipeptidyl aminopeptidase-like protein 6, Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-12-02 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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6HMX
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![BU of 6hmx by Molmil](/molmil-images/mine/6hmx) | |
5FJJ
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![BU of 5fjj by Molmil](/molmil-images/mine/5fjj) | Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-GLUCOSIDASE, ... | Authors: | Agirre, J, Ariza, A, Offen, W.A, Turkenburg, J.P, Roberts, S.M, McNicholas, S, Harris, P.V, McBrayer, B, Dohnalek, J, Cowtan, K.D, Davies, G.J, Wilson, K.S. | Deposit date: | 2015-10-09 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Three-Dimensional Structures of Two Heavily N-Glycosylated Aspergillus Sp. Family Gh3 Beta-D-Glucosidases Acta Crystallogr.,Sect.D, 72, 2016
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5G0Q
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![BU of 5g0q by Molmil](/molmil-images/mine/5g0q) | beta-glucuronidase with an activity-based probe (N-alkyl cyclophellitol aziridine) bound | Descriptor: | (1R,2S,3R,4S,5S,6R)-7-(8-AZIDOOCTYL)-3,4,5-TRIHYDROXY-, BETA-GLUCURONIDASE, GLYCEROL | Authors: | Jin, Y, Wu, L, Jiang, J.B, Overkleeft, H.S, Davies, G.J. | Deposit date: | 2016-03-22 | Release date: | 2017-04-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
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2H96
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![BU of 2h96 by Molmil](/molmil-images/mine/2h96) | Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun NH2-terminal Kinase Inhibitors | Descriptor: | 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE, C-jun-amino-terminal kinase-interacting protein 1, GLYCEROL, ... | Authors: | Abad-Zapatero, C. | Deposit date: | 2006-06-09 | Release date: | 2006-07-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors. J.Med.Chem., 49, 2006
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5FJI
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![BU of 5fji by Molmil](/molmil-images/mine/5fji) | Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-GLUCOSIDASE, ... | Authors: | Agirre, J, Ariza, A, Offen, W.A, Turkenburg, J.P, Roberts, S.M, McNicholas, S, Harris, P.V, McBrayer, B, Dohnalek, J, Cowtan, K.D, Davies, G.J, Wilson, K.S. | Deposit date: | 2015-10-09 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Three-Dimensional Structures of Two Heavily N-Glycosylated Aspergillus Sp. Family Gh3 Beta-D-Glucosidases Acta Crystallogr.,Sect.D, 72, 2016
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5ECP
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![BU of 5ecp by Molmil](/molmil-images/mine/5ecp) | Crystal Structure of FIN219-FIP1 complex with JA, MET and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25001574 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ECR
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![BU of 5ecr by Molmil](/molmil-images/mine/5ecr) | Crystal Structure of FIN219-FIP1 complex with JA, VAL and Mg | Descriptor: | GLUTATHIONE, Glutathione S-transferase U20, Jasmonic acid-amido synthetase JAR1, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7A09
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![BU of 7a09 by Molmil](/molmil-images/mine/7a09) | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-08-07 | Release date: | 2020-10-14 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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5ECM
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![BU of 5ecm by Molmil](/molmil-images/mine/5ecm) | Crystal Structure of FIN219-FIP1 complex with JA and Leu | Descriptor: | GLUTATHIONE, Glutathione S-transferase U20, Jasmonic acid-amido synthetase JAR1, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ECO
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![BU of 5eco by Molmil](/molmil-images/mine/5eco) | Crystal Structure of FIN219-FIP1 complex with JA, Leu and Mg | Descriptor: | GLUTATHIONE, Glutathione S-transferase U20, Jasmonic acid-amido synthetase JAR1, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ECH
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![BU of 5ech by Molmil](/molmil-images/mine/5ech) | Crystal Structure of FIN219-FIP1 complex with JA and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6KOR
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![BU of 6kor by Molmil](/molmil-images/mine/6kor) | Crystal structure of the RRM domain of SYNCRIP | Descriptor: | Heterogeneous nuclear ribonucleoprotein Q | Authors: | Chen, Y, Chan, J, Chen, W, Jobichen, C. | Deposit date: | 2019-08-12 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | SYNCRIP, a new player in pri-let-7a processing. Rna, 26, 2020
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8DWD
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![BU of 8dwd by Molmil](/molmil-images/mine/8dwd) | Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine | Descriptor: | ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... | Authors: | Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P. | Deposit date: | 2022-08-01 | Release date: | 2023-08-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY To Be Published
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6AC5
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![BU of 6ac5 by Molmil](/molmil-images/mine/6ac5) | Crystal structure of RIPK1 death domain GlcNAcylated by EPEC effector NleB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-interacting serine/threonine-protein kinase 1, SULFATE ION | Authors: | Ding, J, Shao, F. | Deposit date: | 2018-07-25 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector. Mol.Cell, 74, 2019
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6B43
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![BU of 6b43 by Molmil](/molmil-images/mine/6b43) | CryoEM structure and atomic model of the Kaposi's sarcoma-associated herpesvirus capsid | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | Authors: | Dai, X.H, Gong, D.Y, Sun, R, Zhou, Z.H. | Deposit date: | 2017-09-25 | Release date: | 2017-11-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication. Nature, 553, 2018
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2MWN
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![BU of 2mwn by Molmil](/molmil-images/mine/2mwn) | Talin-F3 / RIAM N-terminal Peptide complex | Descriptor: | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1 | Authors: | Yang, J, Zhu, L, Zhang, H, Hirbawi, J, Fukuda, K, Dwivedi, P, Liu, J, Byzova, T, Plow, E.F, Wu, J, Qin, J. | Deposit date: | 2014-11-13 | Release date: | 2014-12-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion. Nat Commun, 5, 2014
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2MWI
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![BU of 2mwi by Molmil](/molmil-images/mine/2mwi) | The structure of the carboxy-terminal domain of DNTTIP1 | Descriptor: | Deoxynucleotidyltransferase terminal-interacting protein 1 | Authors: | Schwabe, J.W.R, Muskett, F.W, Itoh, T. | Deposit date: | 2014-11-11 | Release date: | 2015-02-18 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting. Nucleic Acids Res., 43, 2015
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2NO3
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![BU of 2no3 by Molmil](/molmil-images/mine/2no3) | Novel 4-anilinopyrimidines as potent JNK1 Inhibitors | Descriptor: | 2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE, C-JUN-AMINO-TERMINAL KINASE-INTERACTING protein 1, Mitogen-activated protein kinase 8, ... | Authors: | Abad-Zapatero, C. | Deposit date: | 2006-10-24 | Release date: | 2007-04-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg.Med.Chem.Lett., 17, 2007
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4D6K
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![BU of 4d6k by Molmil](/molmil-images/mine/4d6k) | Structure of DNTTIP1 dimerisation domain. | Descriptor: | DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 | Authors: | Itoh, T, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2014-11-11 | Release date: | 2015-02-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Functional Characterization of a Cell Cycle Associated Hdac1/2 Complex Reveals the Structural Basis for Complex Assembly and Nucleosome Targeting. Nucleic Acids Res., 43, 2015
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2OEX
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![BU of 2oex by Molmil](/molmil-images/mine/2oex) | Structure of ALIX/AIP1 V Domain | Descriptor: | Programmed cell death 6-interacting protein | Authors: | Fisher, R.D, Zhai, Q, Robinson, H, Hill, C.P. | Deposit date: | 2007-01-01 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structural and Biochemical Studies of ALIX/AIP1 and Its Role in Retrovirus Budding Cell(Cambridge,Mass.), 128, 2007
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5ECI
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![BU of 5eci by Molmil](/molmil-images/mine/5eci) | Crystal Structure of FIN219-FIP1 complex with JA, ATP and Mg | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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