8DWD

Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine

Summary for 8DWD

• Entry DOI: 10.2210/pdb8dwd/pdb
• Descriptor: Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*AP*(ORP)P*GP*TP*CP*T)-3'), ... (7 entities in total)
• Functional Keywords: protein-dna complex, dna repair, base excision repair, apurinic/apyrimidinic, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 3
• Total formula weight: 48852.72

Authors

Russelburg, L.P.,Demir, M.,David, S.S.,Horvath, M.P. (deposition date: 2022-08-01, release date: 2023-08-09, Last modification date: 2024-05-22)

• Primary citation: Russelburg, L.P.,Demir, M.,Cedeno, K.,David, S.S.,Horvath, M.P.; Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.68 Å)