8DWD
Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine
Summary for 8DWD
Entry DOI | 10.2210/pdb8dwd/pdb |
Descriptor | Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*AP*(ORP)P*GP*TP*CP*T)-3'), ... (7 entities in total) |
Functional Keywords | protein-dna complex, dna repair, base excision repair, apurinic/apyrimidinic, hydrolase, hydrolase-dna complex, hydrolase/dna |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 3 |
Total formula weight | 48852.72 |
Authors | Russelburg, L.P.,Demir, M.,David, S.S.,Horvath, M.P. (deposition date: 2022-08-01, release date: 2023-08-09, Last modification date: 2024-05-22) |
Primary citation | Russelburg, L.P.,Demir, M.,Cedeno, K.,David, S.S.,Horvath, M.P. Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
Download full validation report