8DWD
Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenine DNA glycosylase | polymer | 365 | 41731.6 | 1 | UniProt (P83847) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) Pfam (PF14815) | Geobacillus stearothermophilus | |
| 2 | B (B) | DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3') | polymer | 11 | 3423.2 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*TP*GP*TP*CP*CP*AP*(ORP)P*GP*TP*CP*T)-3') | polymer | 11 | 3207.1 | 1 | synthetic construct | ||
| 4 | D (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 5 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | F, G (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | H, I, J (A, B, C) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 1 - 365 (UniProt: P83847)
| PDB | External Database | Details |
|---|---|---|
| Ser 43 | Glu 43 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48361.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 490.8 | |
| All* | Total formula weight | 48852.7 |
