8DWD
Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Adenine DNA glycosylase | polymer | 365 | 41731.6 | 1 | UniProt (P83847) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) Pfam (PF14815) In PDB | Geobacillus stearothermophilus | |
2 | B | DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3') | polymer | 11 | 3423.2 | 1 | synthetic construct | ||
3 | C | DNA (5'-D(*TP*GP*TP*CP*CP*AP*(ORP)P*GP*TP*CP*T)-3') | polymer | 11 | 3207.1 | 1 | synthetic construct | ||
4 | A | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
5 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
6 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
7 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 1 - 365 (UniProt: P83847)
PDB | External Database | Details |
---|---|---|
Ser 43 | Glu 43 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 48361.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 490.8 | |
All* | Total formula weight | 48852.7 |