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7XB5
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BU of 7xb5 by Molmil
Structure of the ligand-binding domain of S. cerevisiae Upc2 in fusion with T4 lysozyme
Descriptor: fusion protein of Sterol uptake control protein 2 and Endolysin
Authors:Tan, L, Im, Y.J.
Deposit date:2022-03-20
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:Structural basis for activation of fungal sterol receptor Upc2 and azole resistance.
Nat.Chem.Biol., 18, 2022
2VQZ
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BU of 2vqz by Molmil
Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, POLYMERASE BASIC PROTEIN 2
Authors:Guilligay, D, Tarendeau, F, Resa-Infante, P, Coloma, R, Crepin, T, Sehr, P, Lewis, J, Ruigrok, R.W.H, Ortin, J, Hart, D.J, Cusack, S.
Deposit date:2008-03-21
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Basis for CAP Binding by Influenza Virus Polymerase Subunit Pb2.
Nat.Struct.Mol.Biol., 15, 2008
7VPW
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BU of 7vpw by Molmil
Crystal structure of Transportin-1 in complex with BAP1 PY-NLS (residues 706-724)
Descriptor: BRCA1-associated protein 1 (BAP1), Transportin-1
Authors:Yang, T.J, Hsu, S.T.D.
Deposit date:2021-10-18
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.76 Å)
Cite:Tumor suppressor BAP1 nuclear import is governed by transportin-1.
J.Cell Biol., 221, 2022
3CM3
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BU of 3cm3 by Molmil
High Resolution Crystal Structure of the Vaccinia Virus Dual-Specificity Phosphatase VH1
Descriptor: BETA-MERCAPTOETHANOL, Dual specificity protein phosphatase, PHOSPHATE ION
Authors:Koksal, A.C, Cingolani, G.
Deposit date:2008-03-20
Release date:2009-02-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Dimeric Quaternary Structure of the Prototypical Dual Specificity Phosphatase VH1.
J.Biol.Chem., 284, 2009
1O9K
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BU of 1o9k by Molmil
Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide
Descriptor: RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
Authors:Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J.
Deposit date:2002-12-16
Release date:2003-03-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
5YU7
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BU of 5yu7 by Molmil
CRYSTAL STRUCTURE OF EXPORTIN-5
Descriptor: Exportin-5
Authors:Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E.
Deposit date:2017-11-20
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structural Basis for Selective Binding of Export Cargoes by Exportin-5
Structure, 26, 2018
5YU6
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BU of 5yu6 by Molmil
CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP COMPLEX
Descriptor: 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ...
Authors:Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E.
Deposit date:2017-11-20
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Structural Basis for Selective Binding of Export Cargoes by Exportin-5
Structure, 26, 2018
4FQ3
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BU of 4fq3 by Molmil
Crystal structure of transportin/FUS-NLS
Descriptor: Fusion (Involved in t(12;16) in malignant liposarcoma), Transportin-1
Authors:Gong, W, Niu, C, Jia, M, Gao, F.
Deposit date:2012-06-25
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of transportin/FUS-NLS
To be Published
4AY5
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BU of 4ay5 by Molmil
Human O-GlcNAc transferase (OGT) in complex with UDP and glycopeptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GTAB1TIDE, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYL TRANSFERASE 110 KDA SUBUNIT, ...
Authors:Schimpl, M, Zheng, X, Blair, D.E, Schuettelkopf, A.W, Navratilova, I, Aristotelous, T, Ferenbach, A.T, Macnaughtan, M.A, Borodkin, V.S, van Aalten, D.M.F.
Deposit date:2012-06-18
Release date:2012-10-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:O-Glcnac Transferase Invokes Nucleotide Sugar Pyrophosphate Participation in Catalysis
Nat.Chem.Biol., 8, 2012
4AY6
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BU of 4ay6 by Molmil
Human O-GlcNAc transferase (OGT) in complex with UDP-5SGlcNAc and substrate peptide
Descriptor: (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, SULFATE ION, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1, ...
Authors:Schimpl, M, Zheng, X, Blair, D.E, Schuettelkopf, A.W, Navratilova, I, Aristotelous, T, Ferenbach, A.T, Macnaughtan, M.A, Borodkin, V.S, van Aalten, D.M.F.
Deposit date:2012-06-18
Release date:2012-10-24
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:O-Glcnac Transferase Invokes Nucleotide Sugar Pyrophosphate Participation in Catalysis
Nat.Chem.Biol., 8, 2012
1HO8
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BU of 1ho8 by Molmil
CRYSTAL STRUCTURE OF THE REGULATORY SUBUNIT H OF THE V-TYPE ATPASE OF SACCHAROMYCES CEREVISIAE
Descriptor: SULFATE ION, VACUOLAR ATP SYNTHASE SUBUNIT H
Authors:Sagermann, M, Stevens, T.H, Matthews, B.W.
Deposit date:2000-12-10
Release date:2001-06-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae.
Proc.Natl.Acad.Sci.USA, 98, 2001
5F74
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BU of 5f74 by Molmil
Crystal structure of ChREBP:14-3-3 complex bound with AMP
Descriptor: 14-3-3 protein beta/alpha, ADENOSINE MONOPHOSPHATE, Carbohydrate-responsive element-binding protein
Authors:Jung, H, Uyeda, K.
Deposit date:2015-12-07
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR.
J.Biol.Chem., 291, 2016
6W4L
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BU of 6w4l by Molmil
The crystal structure of a single chain H2B-H2A histone chimera from Xenopus laevis
Descriptor: Histone H2B 1.1,Histone H2A type 1, PYROPHOSPHATE
Authors:Warren, C, Bonanno, J.B, Almo, S.C, Shechter, D.
Deposit date:2020-03-11
Release date:2020-05-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structure of a single-chain H2A/H2B dimer.
Acta Crystallogr.,Sect.F, 76, 2020
4HZK
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BU of 4hzk by Molmil
Crystal structure of free CRM1 (crystal form 2)
Descriptor: CRM1 Nuclear transport receptor
Authors:Monecke, T, Neumann, P, Dickmanns, A, Ficner, R.
Deposit date:2012-11-15
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for cooperativity of CRM1 export complex formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
6CVL
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BU of 6cvl by Molmil
Crystal structure of the Escherichia coli ATPgS-bound MetNI methionine ABC transporter in complex with its MetQ binding protein
Descriptor: IODIDE ION, MERCURY (II) ION, MetI transmembrane subunit, ...
Authors:Nguyen, P.T, Kaiser, J.T, Rees, D.C.
Deposit date:2018-03-28
Release date:2018-11-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.953 Å)
Cite:Noncanonical role for the binding protein in substrate uptake by the MetNI methionine ATP Binding Cassette (ABC) transporter.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3DHW
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BU of 3dhw by Molmil
Crystal structure of methionine importer MetNI
Descriptor: D-methionine transport system permease protein metI, Methionine import ATP-binding protein metN
Authors:Rees, D.C, Kaiser, J.T, Kadaba, N.S, Johnson, E, Lee, A.T.
Deposit date:2008-06-18
Release date:2008-08-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation.
Science, 321, 2008
3TUZ
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BU of 3tuz by Molmil
Inward facing conformations of the MetNI methionine ABC transporter: CY5 SeMet soak crystal form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-methionine transport system permease protein metI, Methionine import ATP-binding protein MetN, ...
Authors:Johnson, E, Nguyen, P, Rees, D.C.
Deposit date:2011-09-19
Release date:2011-11-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition.
Protein Sci., 21, 2012
3TUJ
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BU of 3tuj by Molmil
Inward facing conformations of the MetNI methionine ABC transporter: DM crystal form
Descriptor: D-methionine transport system permease protein metI, Methionine import ATP-binding protein MetN
Authors:Johnson, E, Nguyen, P, Rees, D.C.
Deposit date:2011-09-16
Release date:2011-11-30
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition.
Protein Sci., 21, 2012
3TUI
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BU of 3tui by Molmil
Inward facing conformations of the MetNI methionine ABC transporter: CY5 native crystal form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-methionine transport system permease protein metI, Methionine import ATP-binding protein MetN
Authors:Johnson, E, Nguyen, P.T, Rees, D.C.
Deposit date:2011-09-16
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition.
Protein Sci., 21, 2012
8S5B
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BU of 8s5b by Molmil
Crystal structure of the sulfoquinovosyl binding protein (SmoF) from A. tumefaciens sulfo-SMO pathway in complex with SQOctyl ligand
Descriptor: Sulfoquinovosyl glycerol-binding protein SmoF, [(2~{S},3~{S},4~{S},5~{R},6~{S})-6-octoxy-3,4,5-tris(oxidanyl)oxan-2-yl]methanesulfonic acid
Authors:Snow, A.J.D, Sharma, M, Davies, G.J.
Deposit date:2024-02-23
Release date:2024-04-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Capture-and-release of a sulfoquinovose-binding protein on sulfoquinovose-modified agarose.
Org.Biomol.Chem., 22, 2024
1CX8
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BU of 1cx8 by Molmil
CRYSTAL STRUCTURE OF THE ECTODOMAIN OF HUMAN TRANSFERRIN RECEPTOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SAMARIUM (III) ION, TRANSFERRIN RECEPTOR PROTEIN
Authors:Lawrence, C.M, Ray, S, Babyonyshev, M, Galluser, R, Borhani, D, Harrison, S.C.
Deposit date:1999-08-28
Release date:1999-09-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the ectodomain of human transferrin receptor.
Science, 286, 1999
5OR1
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BU of 5or1 by Molmil
BamA structure of Salmonella enterica
Descriptor: Outer membrane protein assembly factor BamA
Authors:Dong, C, Gu, Y.
Deposit date:2017-08-14
Release date:2018-02-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:BamA beta 16C strand and periplasmic turns are critical for outer membrane protein insertion and assembly.
Biochem. J., 474, 2017
7P9V
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BU of 7p9v by Molmil
Cryo EM structure of System XC-
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter
Authors:Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S.
Deposit date:2021-07-28
Release date:2021-11-17
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for redox control by the human cystine/glutamate antiporter system xc .
Nat Commun, 12, 2021
7P9U
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BU of 7p9u by Molmil
Cryo EM structure of System XC- in complex with glutamate
Descriptor: 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter, GLUTAMIC ACID
Authors:Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S.
Deposit date:2021-07-28
Release date:2021-11-17
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular basis for redox control by the human cystine/glutamate antiporter system xc .
Nat Commun, 12, 2021
2GDI
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BU of 2gdi by Molmil
Crystal structure of thiamine pyrophosphate-specific riboswitch in complex with thiamine pyrophosphate
Descriptor: MAGNESIUM ION, POTASSIUM ION, SODIUM ION, ...
Authors:Serganov, A.
Deposit date:2006-03-16
Release date:2006-07-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch.
Nature, 441, 2006

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數據於2024-10-16公開中

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