3KED
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![BU of 3ked by Molmil](/molmil-images/mine/3ked) | Crystal structure of Aminopeptidase N in complex with 2,4-diaminobutyric acid | Descriptor: | 2,4-DIAMINOBUTYRIC ACID, Aminopeptidase N, GLYCEROL, ... | Authors: | Addlagatta, A, Gumpena, R. | Deposit date: | 2009-10-25 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases Chemmedchem, 6, 2011
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5AEQ
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![BU of 5aeq by Molmil](/molmil-images/mine/5aeq) | Neuronal calcium sensor (NCS-1)from Rattus norvegicus | Descriptor: | CALCIUM ION, NEURONAL CALCIUM SENSOR 1, SODIUM ION | Authors: | Saleem, M, Karuppiah, V, Pandalaneni, S, Burgoyne, R, Derrick, J.P, Lian, L.Y. | Deposit date: | 2015-01-08 | Release date: | 2015-02-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-Protein-Coupled Receptor Kinase 1 (Grk1) Peptides Using Different Modes of Interactions. J.Biol.Chem., 290, 2015
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7UJJ
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![BU of 7ujj by Molmil](/molmil-images/mine/7ujj) | Stx2a and DARPin complex | Descriptor: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DARPin, ... | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2022-03-30 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits. Bioengineering (Basel), 9, 2022
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6FGB
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![BU of 6fgb by Molmil](/molmil-images/mine/6fgb) | Human FcRn extra-cellular domain complexed with Fab fragment of Rozanolixizumab | Descriptor: | 1519.g57- Heavy chain, 1519.g57- Light chain, Beta-2-microglobulin, ... | Authors: | Sarkar, K, Ceska, T, Meier, C. | Deposit date: | 2018-01-10 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration. MAbs, 10, 2018
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4ZUN
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![BU of 4zun by Molmil](/molmil-images/mine/4zun) | Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a thiol inhibitor | Descriptor: | 5-[(3-aminopropyl)amino]pentane-1-thiol, Acetylpolyamine aminohydrolase, GLYCEROL, ... | Authors: | Decroos, C, Christianson, D.W. | Deposit date: | 2015-05-17 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase. Biochemistry, 54, 2015
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5CM7
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![BU of 5cm7 by Molmil](/molmil-images/mine/5cm7) | |
5C4I
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![BU of 5c4i by Molmil](/molmil-images/mine/5c4i) | Structure of an Oxalate Oxidoreductase | Descriptor: | IRON/SULFUR CLUSTER, MAGNESIUM ION, Oxalate oxidoreductase subunit alpha, ... | Authors: | Gibson, M.I, Brignole, E.J, Pierce, E, Can, M, Ragsdale, S.W, Drennan, C.L. | Deposit date: | 2015-06-18 | Release date: | 2015-07-01 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.274 Å) | Cite: | The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism. Biochemistry, 54, 2015
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6FMP
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![BU of 6fmp by Molmil](/molmil-images/mine/6fmp) | Keap1 - peptide complex | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACY-ASP-GLU-GLU-THR-GLY-GLU-PHE, ... | Authors: | Talapatra, S.K, Kozielski, F, Wells, G, Georgakopoulos, N.D. | Deposit date: | 2018-02-01 | Release date: | 2018-08-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids. Chembiochem, 19, 2018
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3ZN2
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![BU of 3zn2 by Molmil](/molmil-images/mine/3zn2) | protein engineering of halohydrin dehalogenase | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETATE ION, HALOHYDRIN DEHALOGENASE, ... | Authors: | Schallmey, M, Jekel, P, Tang, L, Majeric-Elenkov, M, Hoeffken, H.W, Hauer, B, Janssen, D.B. | Deposit date: | 2013-02-13 | Release date: | 2014-03-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Single Point Mutation Enhances Hydroxynitrile Synthesis by Halohydrin Dehalogenase. Enzyme.Microb.Technol., 70, 2015
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6G2X
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![BU of 6g2x by Molmil](/molmil-images/mine/6g2x) | Crystal structure of the p97 D2 domain in a helical split-washer conformation | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | Authors: | Stach, L, Morgan, R.M.L, Freemont, P.S. | Deposit date: | 2018-03-23 | Release date: | 2019-04-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.078 Å) | Cite: | Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding. Febs Lett., 594, 2020
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3ZX7
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![BU of 3zx7 by Molmil](/molmil-images/mine/3zx7) | Complex of lysenin with phosphocholine | Descriptor: | LYSENIN, PHOSPHATE ION, PHOSPHOCHOLINE, ... | Authors: | De Colibus, L, Sonnen, A.F.P, Morris, K.J, Siebert, C.A, Abrusci, P, Plitzko, J, Hodnik, V, Leippe, M, Volpi, E, Anderluh, G, Gilbert, R.J.C. | Deposit date: | 2011-08-08 | Release date: | 2012-09-19 | Last modified: | 2012-10-03 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition. Structure, 20, 2012
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7WU1
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![BU of 7wu1 by Molmil](/molmil-images/mine/7wu1) | Crystal structure of phospholipase D from Moritella sp. JT01 | Descriptor: | 1,2-ETHANEDIOL, Phospholipase D, SODIUM ION | Authors: | Wang, Y.H, Mao, X.J, Wang, J, Wang, F.H. | Deposit date: | 2022-02-05 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of phospholipase D from Moritella sp. JT01 To Be Published
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6GAQ
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![BU of 6gaq by Molmil](/molmil-images/mine/6gaq) | Crystal structure of oxidised Flavodoxin 2 from Bacillus cereus | Descriptor: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, Flavodoxin, ... | Authors: | Lofstad, M, Gudim, I, Hersleth, H.-P. | Deposit date: | 2018-04-12 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Characterization of Different Flavodoxin Reductase-Flavodoxin (FNR-Fld) Interactions Reveals an Efficient FNR-Fld Redox Pair and Identifies a Novel FNR Subclass. Biochemistry, 57, 2018
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3L0O
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![BU of 3l0o by Molmil](/molmil-images/mine/3l0o) | Structure of RNA-free Rho transcription termination factor from Thermotoga maritima | Descriptor: | SODIUM ION, SULFATE ION, Transcription termination factor rho, ... | Authors: | Canals, A, Uson, I, Coll, M. | Deposit date: | 2009-12-10 | Release date: | 2010-05-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The Structure of RNA-Free Rho Termination Factor Indicates a Dynamic Mechanism of Transcript Capture J.Mol.Biol., 400, 2010
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6G30
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![BU of 6g30 by Molmil](/molmil-images/mine/6g30) | Crystal structure of the p97 D2 domain in a helical split-washer conformation | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | Authors: | Stach, L, Morgan, R.M.L, Freemont, P.S. | Deposit date: | 2018-03-23 | Release date: | 2019-04-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.418 Å) | Cite: | Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding. Febs Lett., 594, 2020
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3KLB
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5A8E
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![BU of 5a8e by Molmil](/molmil-images/mine/5a8e) | thermostabilised beta1-adrenoceptor with rationally designed inverse agonist 7-methylcyanopindolol bound | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 4-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-7-methyl-1H-indole-2-carbonitrile, ... | Authors: | Sato, T, Baker, J.G, Warne, T, Brown, G.A, Congreve, M, Leslie, A.G.W, Tate, C.G. | Deposit date: | 2015-07-15 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound Beta1-Adrenergic Receptor. Mol.Pharmacol., 88, 2015
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4ZUQ
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![BU of 4zuq by Molmil](/molmil-images/mine/4zuq) | Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor | Descriptor: | 6-amino-N-hydroxyhexanamide, Acetylpolyamine aminohydrolase, GLYCEROL, ... | Authors: | Decroos, C, Christianson, D.W. | Deposit date: | 2015-05-17 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase. Biochemistry, 54, 2015
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3ZPQ
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![BU of 3zpq by Molmil](/molmil-images/mine/3zpq) | Thermostabilised turkey beta1 adrenergic receptor with 4-(piperazin-1- yl)-1H-indole bound (compound 19) | Descriptor: | 4-(PIPERAZIN-1-YL)-1H-INDOLE, BETA-1 ADRENERGIC RECEPTOR, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Christopher, J.A, Congreve, M, Dore, A.S, Marshall, F.H, Myszka, D.G, Brown, J, Koglin, M, Tehan, B, Errey, J.C, Tate, C.G, Warne, T. | Deposit date: | 2013-03-01 | Release date: | 2013-04-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Biophysical Fragment Screening of the Beta1-Adrenergic Receptor: Identification of High Affinity Aryl Piperazine Leads Using Structure-Based Drug Design. J.Med.Chem., 56, 2013
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5AXA
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5AXB
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![BU of 5axb by Molmil](/molmil-images/mine/5axb) | Crystal structure of mouse SAHH complexed with noraristeromycin | Descriptor: | (1S,2R,3S,4R)-4-(6-aminopurin-9-yl)cyclopentane-1,2,3-triol, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Kusakabe, Y, Ishihara, M, Tanaka, N. | Deposit date: | 2015-07-24 | Release date: | 2016-07-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of mouse SAHH complexed with noraristeromycin To Be Published
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3K2O
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![BU of 3k2o by Molmil](/molmil-images/mine/3k2o) | Structure of an oxygenase | Descriptor: | ACETATE ION, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, CHLORIDE ION, ... | Authors: | Krojer, T, McDonough, M.A, Clifton, I.J, Mantri, M, Ng, S.S, Pike, A.C.W, Butler, D.S, Webby, C.J, Kochan, G, Bhatia, C, Bray, J.E, Chaikuad, A, Gileadi, O, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Schofield, C.J, Kavanagh, K.L, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-30 | Release date: | 2009-11-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6. J.Mol.Biol., 401, 2010
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3K3L
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![BU of 3k3l by Molmil](/molmil-images/mine/3k3l) | |
5COZ
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![BU of 5coz by Molmil](/molmil-images/mine/5coz) | |
6FOP
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![BU of 6fop by Molmil](/molmil-images/mine/6fop) | Glycoside hydrolase family 81 from Clostridium thermocellum (CtLam81A), Mutant E515A | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Correia, M.A.S.C, Carvalho, A.L. | Deposit date: | 2018-02-08 | Release date: | 2019-03-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Novel insights into the degradation of beta-1,3-glucans by the cellulosome of Clostridium thermocellum revealed by structure and function studies of a family 81 glycoside hydrolase. Int.J.Biol.Macromol., 117, 2018
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