PDB: 12060 resultsInfo pagesStatus searchChemie searchBIRD

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6WZ5	Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin Descriptor: DNA (153-MER), Histone H2A, Histone H2B 1.1, ... Authors: Halic, M, Bilokapic, S. Deposit date: 2020-05-13 Release date: 2020-09-16 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Nature, 585, 2020
6WZ9	Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin Descriptor: DNA, Histone H2A, Histone H2B 1.1, ... Authors: Halic, M, Bilokapic, S. Deposit date: 2020-05-13 Release date: 2020-09-16 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Nature, 585, 2020
7CWB	Ambient-Temperature Serial Femtosecond X-ray Crystal structure of SARS-CoV-2 Main Protease at 1.9 A Resolution (C121) Descriptor: 3C-like proteinase Authors: DeMirci, H. Deposit date: 2020-08-27 Release date: 2020-09-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing. Structure, 29, 2021
7CWC	Ambient-Temperature Serial Femtosecond X-ray Crystal structure of SARS-CoV-2 Main Protease at 2.1 A Resolution (P212121) Descriptor: 3C-like proteinase Authors: DeMirci, H. Deposit date: 2020-08-27 Release date: 2020-09-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing. Structure, 29, 2021
6X0N	Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin Descriptor: DNA (167-MER), Histone H2A, Histone H2B 1.1, ... Authors: Halic, M, Bilokapic, S. Deposit date: 2020-05-16 Release date: 2020-09-16 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (10 Å) Cite: Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Nature, 585, 2020
5PUF	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 193) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.82 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PO6	PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10157a Descriptor: 1,2-ETHANEDIOL, 4-(4-bromophenyl)-1H-pyrazol-3-amine, Bromodomain-containing protein 1, ... Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-15 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.61 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PUV	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 209) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.69 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5POU	PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10954a Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, N-(1-benzylpiperidin-4-yl)-N'-methylurea, ... Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-15 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PVA	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 224) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.98 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PP4	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 4) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.92 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PVM	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 237) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PW7	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 258) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PPM	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 23) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.87 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PPO	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 25) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.84 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PPW	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 33) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.45 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PQ5	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 42) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PQL	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 58) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.52 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PQZ	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 72) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.58 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PRG	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 88) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.68 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PRV	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 102) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.62 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PS6	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 114) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.52 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PSG	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 124) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PSW	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 140) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.53 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PTC	PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 156) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION Authors: Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. Deposit date: 2017-02-07 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.78 Å) Cite: A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017

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