Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7CWB

Ambient-Temperature Serial Femtosecond X-ray Crystal structure of SARS-CoV-2 Main Protease at 1.9 A Resolution (C121)

Summary for 7CWB
Entry DOI10.2210/pdb7cwb/pdb
Descriptor3C-like proteinase (2 entities in total)
Functional Keywordscovid19, sars-cov-2, drug target, serial femtosecond x-ray crystallography, sfx, xfel, virus protein, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains1
Total formula weight33825.55
Authors
DeMirci, H. (deposition date: 2020-08-27, release date: 2020-09-30, Last modification date: 2023-11-29)
Primary citationDurdagi, S.,Dag, C.,Dogan, B.,Yigin, M.,Avsar, T.,Buyukdag, C.,Erol, I.,Ertem, F.B.,Calis, S.,Yildirim, G.,Orhan, M.D.,Guven, O.,Aksoydan, B.,Destan, E.,Sahin, K.,Besler, S.O.,Oktay, L.,Shafiei, A.,Tolu, I.,Ayan, E.,Yuksel, B.,Peksen, A.B.,Gocenler, O.,Yucel, A.D.,Can, O.,Ozabrahamyan, S.,Olkan, A.,Erdemoglu, E.,Aksit, F.,Tanisali, G.,Yefanov, O.M.,Barty, A.,Tolstikova, A.,Ketawala, G.K.,Botha, S.,Dao, E.H.,Hayes, B.,Liang, M.,Seaberg, M.H.,Hunter, M.S.,Batyuk, A.,Mariani, V.,Su, Z.,Poitevin, F.,Yoon, C.H.,Kupitz, C.,Sierra, R.G.,Snell, E.H.,DeMirci, H.
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing.
Structure, 29:1382-1396.e6, 2021
Cited by
PubMed: 34403647
DOI: 10.1016/j.str.2021.07.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon