8GT1
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![BU of 8gt1 by Molmil](/molmil-images/mine/8gt1) | Crystal structure of human cardiac alpha actin A108G mutant (ADP-Pi state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GSW
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![BU of 8gsw by Molmil](/molmil-images/mine/8gsw) | Crystal structure of human cardiac alpha actin A108G mutant (AMPPNP state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GT2
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![BU of 8gt2 by Molmil](/molmil-images/mine/8gt2) | Crystal structure of human cardiac alpha actin P109A mutant (AMPPNP state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GT5
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![BU of 8gt5 by Molmil](/molmil-images/mine/8gt5) | Crystal structure of human cardiac alpha actin Q137A mutant (ADP-Pi state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GT3
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![BU of 8gt3 by Molmil](/molmil-images/mine/8gt3) | Crystal structure of human cardiac alpha actin P109A mutant (ADP-Pi state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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3MN6
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![BU of 3mn6 by Molmil](/molmil-images/mine/3mn6) | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. | Deposit date: | 2010-04-21 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3MN9
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![BU of 3mn9 by Molmil](/molmil-images/mine/3mn9) | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. | Deposit date: | 2010-04-21 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3MMV
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![BU of 3mmv by Molmil](/molmil-images/mine/3mmv) | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. | Deposit date: | 2010-04-20 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010
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8F8Q
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![BU of 8f8q by Molmil](/molmil-images/mine/8f8q) | Cryo-EM structure of the CapZ-capped barbed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8D14
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![BU of 8d14 by Molmil](/molmil-images/mine/8d14) | Helical ADP-Pi-F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-05-26 | Release date: | 2022-09-07 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure. Nature, 611, 2022
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8D18
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![BU of 8d18 by Molmil](/molmil-images/mine/8d18) | Straight ADP-F-actin 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-05-26 | Release date: | 2022-09-07 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure. Nature, 611, 2022
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8D15
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![BU of 8d15 by Molmil](/molmil-images/mine/8d15) | Bent ADP-F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-05-26 | Release date: | 2022-09-07 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure. Nature, 611, 2022
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8D13
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![BU of 8d13 by Molmil](/molmil-images/mine/8d13) | Helical ADP-F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-05-26 | Release date: | 2022-09-07 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure. Nature, 611, 2022
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8D17
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![BU of 8d17 by Molmil](/molmil-images/mine/8d17) | Straight ADP-F-actin 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-05-26 | Release date: | 2022-09-07 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure. Nature, 611, 2022
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6TU4
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![BU of 6tu4 by Molmil](/molmil-images/mine/6tu4) | Structure of Plasmodium Actin1 filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | Authors: | Vahokoski, J, Calder, L.J, Lopez, A.J, Rosenthal, P.B, Kursula, I. | Deposit date: | 2020-01-02 | Release date: | 2021-01-13 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | High-resolution structures of malaria parasite actomyosin and actin filaments. Plos Pathog., 18, 2022
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8F8T
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![BU of 8f8t by Molmil](/molmil-images/mine/8f8t) | Cryo-EM structure of the Tropomodulin-capped pointed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8D16
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![BU of 8d16 by Molmil](/molmil-images/mine/8d16) | Bent ADP-Pi-F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-05-26 | Release date: | 2022-09-07 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure. Nature, 611, 2022
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8EFI
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![BU of 8efi by Molmil](/molmil-images/mine/8efi) | Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in the rigor form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | Deposit date: | 2022-09-08 | Release date: | 2022-11-23 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. J.Gen.Physiol., 155, 2023
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8F8P
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![BU of 8f8p by Molmil](/molmil-images/mine/8f8p) | Cryo-EM structure of F-actin in the ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.26 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8F8R
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![BU of 8f8r by Molmil](/molmil-images/mine/8f8r) | Cryo-EM structure of the free barbed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8F8S
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![BU of 8f8s by Molmil](/molmil-images/mine/8f8s) | Cryo-EM structure of the free pointed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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3AA1
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![BU of 3aa1 by Molmil](/molmil-images/mine/3aa1) | Crystal structure of Actin capping protein in complex with the Cp-binding motif derived from CKIP-1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 23mer peptide from Pleckstrin homology domain-containing family O member 1, F-actin-capping protein subunit alpha-1, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-11 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
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1C0G
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![BU of 1c0g by Molmil](/molmil-images/mine/1c0g) | CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 228: Q228K/T229A/A230Y/E360H) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, PROTEIN (CHIMERIC ACTIN), ... | Authors: | Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T. | Deposit date: | 1999-07-16 | Release date: | 2000-03-01 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras. J.Mol.Biol., 296, 2000
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1DEJ
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![BU of 1dej by Molmil](/molmil-images/mine/1dej) | CRYSTAL STRUCTURE OF A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 646: Q228K/T229A/A230Y/A231K/S232E/E360H) IN COMPLEX WITH HUMAN GELSOLIN SEGMENT 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHIMERIC ACTIN, ... | Authors: | Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T. | Deposit date: | 1999-11-15 | Release date: | 2000-03-01 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras. J.Mol.Biol., 296, 2000
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8ENC
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![BU of 8enc by Molmil](/molmil-images/mine/8enc) | Helical reconstruction of the human cardiac actin-tropomyosin-myosin loop 4 7G mutant complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | Deposit date: | 2022-09-29 | Release date: | 2022-11-23 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. J.Gen.Physiol., 155, 2023
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