5O2L
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![BU of 5o2l by Molmil](/molmil-images/mine/5o2l) | Myosin VI motor domain in the Pre-Transition State | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... | Authors: | Isabet, T, Benisty, H, Houdusse, A. | Deposit date: | 2017-05-22 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8AAU
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![BU of 8aau by Molmil](/molmil-images/mine/8aau) | LIM Domain Kinase 1 (LIMK1) bound to LIMKi3 | Descriptor: | 1,2-ETHANEDIOL, LIM domain kinase 1, MAGNESIUM ION, ... | Authors: | Mathea, S, Salah, E, Hanke, T, Knapp, S. | Deposit date: | 2022-07-03 | Release date: | 2022-08-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. J.Med.Chem., 65, 2022
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2ATX
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![BU of 2atx by Molmil](/molmil-images/mine/2atx) | Crystal Structure of the TC10 GppNHp complex | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, small GTP binding protein TC10 | Authors: | Hemsath, L, Dvorsky, R, Fiegen, D, Carlier, M.F, Ahmadian, M.R. | Deposit date: | 2005-08-26 | Release date: | 2005-09-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | An electrostatic steering mechanism of Cdc42 recognition by Wiskott-Aldrich syndrome proteins Mol.Cell, 20, 2005
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2LSR
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![BU of 2lsr by Molmil](/molmil-images/mine/2lsr) | Solution structure of harmonin N terminal domain in complex with a exon68 encoded peptide of cadherin23 | Descriptor: | Harmonin, peptide from Cadherin-23 | Authors: | Pan, L, Wu, L, Zhang, C, Zhang, M. | Deposit date: | 2012-05-04 | Release date: | 2012-08-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia. J.Biol.Chem., 287, 2012
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4QWO
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![BU of 4qwo by Molmil](/molmil-images/mine/4qwo) | 1.52 Angstrom Crystal Structure of A42R Profilin-like Protein from Monkeypox Virus Zaire-96-I-16 | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ... | Authors: | Minasov, G, Shuvalova, L, Dubrovska, I, Flores, K, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-07-16 | Release date: | 2014-08-06 | Last modified: | 2022-10-12 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structure of the Monkeypox virus profilin-like protein A42R reveals potential functional differences from cellular profilins. Acta Crystallogr.,Sect.F, 78, 2022
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5XC1
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![BU of 5xc1 by Molmil](/molmil-images/mine/5xc1) | Crystal structure of the complex of an aromatic mutant (W6A) of an alkali thermostable GH10 Xylanase from Bacillus sp. NG-27 with S-1,2-Propanediol | Descriptor: | Beta-xylanase, MAGNESIUM ION, S-1,2-PROPANEDIOL, ... | Authors: | Bansia, H, Mahanta, P, Ramakumar, S. | Deposit date: | 2017-03-21 | Release date: | 2018-03-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Small Glycols Discover Cryptic Pockets on Proteins for Fragment-Based Approaches. J.Chem.Inf.Model., 2021
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5XC0
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![BU of 5xc0 by Molmil](/molmil-images/mine/5xc0) | |
7UAK
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![BU of 7uak by Molmil](/molmil-images/mine/7uak) | |
5EFD
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![BU of 5efd by Molmil](/molmil-images/mine/5efd) | Crystal structure of a surface pocket creating mutant (W6A) of an alkali thermostable GH10 xylanase from Bacillus sp. NG-27 | Descriptor: | 1,2-ETHANEDIOL, Beta-xylanase, CHLORIDE ION, ... | Authors: | Mahanta, P, Bhardwaj, A, Reddy, V.S, Ramakumar, S. | Deposit date: | 2015-10-23 | Release date: | 2016-10-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.674 Å) | Cite: | Small Glycols Discover Cryptic Pockets on Proteins for Fragment-Based Approaches. J.Chem.Inf.Model., 2021
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7UZE
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![BU of 7uze by Molmil](/molmil-images/mine/7uze) | Erythrocyte ankyrin-1 complex class 2 local refinement of AQP1 (C4 symmetry applied) | Descriptor: | Aquaporin-1, CHOLESTEROL | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-09 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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2V6H
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![BU of 2v6h by Molmil](/molmil-images/mine/2v6h) | Crystal structure of the C1 domain of cardiac myosin binding protein-C | Descriptor: | MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE | Authors: | Govata, L, Carpenter, L, Da Fonseca, P.C.A, Helliwell, J.R, Rizkallah, P.J, Flashman, E, Chayen, N.E, Redwood, C, Squire, J.M. | Deposit date: | 2007-07-18 | Release date: | 2008-07-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy. J. Mol. Biol., 378, 2008
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4F7R
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8H93
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![BU of 8h93 by Molmil](/molmil-images/mine/8h93) | Structure of dimeric mouse SCMC core complex | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | Authors: | Chi, P, Ou, G, Han, Z, Li, J, Deng, D. | Deposit date: | 2022-10-24 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H94
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![BU of 8h94 by Molmil](/molmil-images/mine/8h94) | Structure of mouse SCMC bound with KH domain of FILIA | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | Authors: | Chi, P, Ou, G, Han, Z, Li, J, Deng, D. | Deposit date: | 2022-10-24 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H96
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![BU of 8h96 by Molmil](/molmil-images/mine/8h96) | Structure of mouse SCMC core complex | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | Authors: | Chi, P, Ou, G, Li, J, Han, Z, Deng, D. | Deposit date: | 2022-10-24 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H95
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![BU of 8h95 by Molmil](/molmil-images/mine/8h95) | Structure of mouse SCMC bound with full-length FILIA | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | Authors: | Chi, P, Ou, G, Han, Z, Li, L, Deng, D. | Deposit date: | 2022-10-24 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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7BRQ
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![BU of 7brq by Molmil](/molmil-images/mine/7brq) | Crystal structure of human FAM134B LIR fused to human GABARAP | Descriptor: | GLYCEROL, Reticulophagy regulator 1,Gamma-aminobutyric acid receptor-associated protein | Authors: | Yamasaki, A, Noda, N.N. | Deposit date: | 2020-03-29 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.404 Å) | Cite: | Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
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7BRT
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![BU of 7brt by Molmil](/molmil-images/mine/7brt) | Crystal structure of Sec62 LIR fused to GABARAP | Descriptor: | Translocation protein SEC62,Gamma-aminobutyric acid receptor-associated protein | Authors: | Yamasaki, A, Noda, N.N. | Deposit date: | 2020-03-30 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
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7BRU
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![BU of 7bru by Molmil](/molmil-images/mine/7bru) | Crystal structure of human RTN3 LIR fused to human GABARAP | Descriptor: | PHOSPHATE ION, Reticulon-3,Gamma-aminobutyric acid receptor-associated protein | Authors: | Yamasaki, A, Noda, N.N. | Deposit date: | 2020-03-30 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.149 Å) | Cite: | Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
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8JJS
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![BU of 8jjs by Molmil](/molmil-images/mine/8jjs) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | Authors: | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | Deposit date: | 2023-05-31 | Release date: | 2023-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.534 Å) | Cite: | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
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2ETK
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![BU of 2etk by Molmil](/molmil-images/mine/2etk) | Crystal Structure of ROCK 1 bound to hydroxyfasudil | Descriptor: | 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-27 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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1MK7
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![BU of 1mk7 by Molmil](/molmil-images/mine/1mk7) | CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA | Descriptor: | Integrin Beta3, TALIN | Authors: | Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | Deposit date: | 2002-08-28 | Release date: | 2003-01-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
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1MIX
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![BU of 1mix by Molmil](/molmil-images/mine/1mix) | Crystal structure of a FERM domain of Talin | Descriptor: | Talin | Authors: | Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | Deposit date: | 2002-08-23 | Release date: | 2003-01-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural determinants of integrin recognition by talin Mol.Cell, 11, 2003
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1TJF
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![BU of 1tjf by Molmil](/molmil-images/mine/1tjf) | The crystal structure of the N-terminal domain of CAP indicates variable oligomerisation | Descriptor: | Adenylyl cyclase-associated protein, SULFATE ION | Authors: | Mohd Yusof, A, Hu, N.J, Wlodawer, A, Hofmann, A. | Deposit date: | 2004-06-04 | Release date: | 2005-02-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structural evidence for variable oligomerization of the N-terminal domain of cyclase-associated protein (CAP). Proteins, 58, 2005
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7MQ9
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![BU of 7mq9 by Molmil](/molmil-images/mine/7mq9) | Cryo-EM structure of the human SSU processome, state pre-A1* | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Vanden Broeck, A, Singh, S, Klinge, S. | Deposit date: | 2021-05-05 | Release date: | 2021-09-22 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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