PDB: 1001 resultsInfo pagesStatus searchChemie searchBIRD

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8K2C	Cryo-EM structure of the human 80S ribosome with Tigecycline Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Li, X, Wang, M, Cheng, J. Deposit date: 2023-07-12 Release date: 2024-07-10 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
6XJP	Crystal Structure of KPT-185 bound to CRM1 (537-DLTVK-541 to GLCEQ) Descriptor: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... Authors: Baumhardt, J.M, Chook, Y.M. Deposit date: 2020-06-24 Release date: 2021-01-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.802 Å) Cite: Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
6XJT	Crystal Structure of KPT-8602 bound to CRM1 (537-DLTVK-541 to GLCEQ) Descriptor: (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M, Chook, Y.M. Deposit date: 2020-06-24 Release date: 2021-01-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.406 Å) Cite: Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
8J07	96nm repeat of human respiratory doublet microtubule and associated axonemal complexes Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ... Authors: Gui, M, Brown, A. Deposit date: 2023-04-09 Release date: 2023-07-26 Last modified: 2023-08-02 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Axonemal structures reveal mechanoregulatory and disease mechanisms. Nature, 618, 2023
6F1Z	Roadblock-1 region of the dynein tail/dynactin/BICDR1 complex Descriptor: Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain roadblock-type 1 Authors: Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. Deposit date: 2017-11-23 Release date: 2018-01-17 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
4UJ5	Crystal structure of human Rab11-Rabin8-FIP3 Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ... Authors: Vetter, M, Lorentzen, E. Deposit date: 2015-04-08 Release date: 2015-08-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.604 Å) Cite: Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11. Nat.Struct.Mol.Biol., 22, 2015
4UJ4	Crystal structure of human Rab11-Rabin8-FIP3 Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab-3A-interacting protein, ... Authors: Vetter, M, Lorentzen, E. Deposit date: 2015-04-08 Release date: 2015-08-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11. Nat. Struct. Mol. Biol., 22, 2015
4UJ3	Crystal structure of human Rab11-Rabin8-FIP3 Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ... Authors: Vetter, M, Lorentzen, E. Deposit date: 2015-04-08 Release date: 2015-08-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11. Nat.Struct.Mol.Biol., 22, 2015
5EZ5	Crystal structure of active Rab11A (S20V) in complex with GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-11A Authors: Shin, Y.-C, Yoon, J.H, Park, H.H. Deposit date: 2015-11-26 Release date: 2016-12-07 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of active Rab11A (S20V) in complex with GTP To Be Published
6A3A	MVM NES mutant Nm2 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6A3E	MVM NES mutant Nm15 in complex with CRM1-Ran-RanBP1 Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
5FBW	PI4KB in complex with Rab11 and the MI369 Inhibitor Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... Authors: Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. Deposit date: 2015-12-14 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.487 Å) Cite: PI4KB in complex with Rab11 and the MI369 Inhibitor To Be Published
6A3C	MVM NES mutant Nm12 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6A38	MVM NS2 NES in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6A3B	MVM NES mutant Nm13 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
2IV8	beta appendage in complex with b-arrestin peptide Descriptor: AP-2 COMPLEX SUBUNIT BETA-1, BETA-ARRESTIN-1 Authors: Ford, M.G.J, Schmid, E.M, McMahon, H.T. Deposit date: 2006-06-08 Release date: 2007-06-12 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Role of the Ap2 Beta-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly. Plos Biol., 4, 2006
2JJU	Structure of human signal regulatory protein (sirp) beta Descriptor: CHLORIDE ION, SIGNAL REGULATORY PROTEIN BETA-1, SULFATE ION Authors: Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. Deposit date: 2008-04-22 Release date: 2008-08-05 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47. Mol.Cell, 31, 2008
5FBR	PI4KB in complex with Rab11 and the MI359 Inhibitor Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... Authors: Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. Deposit date: 2015-12-14 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.28 Å) Cite: PI4KB in complex with Rab11 and the MI359 Inhibitor To Be Published
5ET1	Crystal structure of Myo3b-ARB1 in complex with Espin1-AR Descriptor: Espin, GLYCEROL, Myosin-IIIb Authors: Liu, H, Li, J, liu, W, Zhang, M. Deposit date: 2015-11-17 Release date: 2016-02-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin Elife, 5, 2016
5EUQ	Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with a potent and selective inhibitor in complex with GDP loaded Rab11 Descriptor: GUANOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... Authors: Burke, J.E, Fowler, M.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase III beta. J.Med.Chem., 59, 2016
4GMX	Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-08-16 Release date: 2012-10-17 Last modified: 2012-12-12 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood, 120, 2012
5FBQ	PI4KB in complex with Rab11 and the MI358 Inhibitor Descriptor: GUANOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... Authors: Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. Deposit date: 2015-12-14 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.789 Å) Cite: PI4KB in complex with Rab11 and the MI358 Inhibitor To Be Published
5FBL	PI4KB in complex with Rab11 and the MI356 Inhibitor Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... Authors: Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. Deposit date: 2015-12-14 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.372 Å) Cite: PI4KB in complex with Rab11 and the MI356 Inhibitor To Be Published
5FBV	PI4KB in complex with Rab11 and the MI364 Inhibitor Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... Authors: Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. Deposit date: 2015-12-14 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.285 Å) Cite: PI4KB in complex with Rab11 and the MI364 Inhibitor To Be Published
2F9M	3D structure of active human Rab11b GTPase Descriptor: MAGNESIUM ION, NICKEL (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Scapin, S.M.N, Guimaraes, B.G, Zanchin, N.I.T. Deposit date: 2005-12-06 Release date: 2006-04-04 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform. J.Struct.Biol., 154, 2006

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