4B3Q
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![BU of 4b3q by Molmil](/molmil-images/mine/4b3q) | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | Descriptor: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, P51 RT, PRIMER DNA, ... | Authors: | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | Deposit date: | 2012-07-25 | Release date: | 2013-01-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (5 Å) | Cite: | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation Nat.Struct.Mol.Biol., 20, 2013
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3P2X
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![BU of 3p2x by Molmil](/molmil-images/mine/3p2x) | Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity | Descriptor: | CHLORIDE ION, Insulin, PHENOL, ... | Authors: | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2010-10-04 | Release date: | 2011-11-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
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3P33
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![BU of 3p33 by Molmil](/molmil-images/mine/3p33) | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity | Descriptor: | CHLORIDE ION, Insulin, PHENOL, ... | Authors: | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2010-10-04 | Release date: | 2011-11-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
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4FPS
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![BU of 4fps by Molmil](/molmil-images/mine/4fps) | tRNA-Guanine Transglycosylase in complex with adamantyl-substituted lin-benzoguanine ligand | Descriptor: | 6-amino-2-(methylamino)-4-(2-{[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-ylmethyl]amino}ethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | Authors: | Immekus, F, Klebe, G. | Deposit date: | 2012-06-22 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Studies on TGT homodimer interface To be Published
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4FR6
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![BU of 4fr6 by Molmil](/molmil-images/mine/4fr6) | |
4GX6
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![BU of 4gx6 by Molmil](/molmil-images/mine/4gx6) | |
3OB1
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![BU of 3ob1 by Molmil](/molmil-images/mine/3ob1) | |
4GX4
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![BU of 4gx4 by Molmil](/molmil-images/mine/4gx4) | |
3O3Y
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![BU of 3o3y by Molmil](/molmil-images/mine/3o3y) | |
5NQ6
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![BU of 5nq6 by Molmil](/molmil-images/mine/5nq6) | Crystal structure of the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE from Escherichia coli at 2.40 Angstrom Resolution | Descriptor: | GLYCEROL, SULFATE ION, Sulfur acceptor protein CsdE | Authors: | Penya-Soler, E, Aranda, J, Lopez-Estepa, M, Gomez, S, Garces, F, Coll, M, Fernandez, F.J, Vega, M.C. | Deposit date: | 2017-04-19 | Release date: | 2018-03-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE. PLoS ONE, 12, 2017
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6DXL
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![BU of 6dxl by Molmil](/molmil-images/mine/6dxl) | Linked amidobenzimidazole STING agonist | Descriptor: | 1,1'-(butane-1,4-diyl)bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1H-benzimidazole-5-carboxamide}, CALCIUM ION, Stimulator of interferon protein | Authors: | Concha, N.O. | Deposit date: | 2018-06-29 | Release date: | 2018-11-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature, 564, 2018
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4GX3
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![BU of 4gx3 by Molmil](/molmil-images/mine/4gx3) | |
3OB2
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![BU of 3ob2 by Molmil](/molmil-images/mine/3ob2) | |
4E4B
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![BU of 4e4b by Molmil](/molmil-images/mine/4e4b) | |
5T5W
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![BU of 5t5w by Molmil](/molmil-images/mine/5t5w) | Structure of an affinity matured lambda-IFN/IFN-lambdaR1/IL-10Rbeta receptor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon lambda receptor 1, Interferon lambda-3, ... | Authors: | Mendoza, J.L, Jude, K.M, Garcia, K.C. | Deposit date: | 2016-08-31 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.847 Å) | Cite: | The IFN-lambda-IFN-lambda R1-IL-10R beta Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity. Immunity, 46, 2017
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4H79
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![BU of 4h79 by Molmil](/molmil-images/mine/4h79) | Crystal structure of CasB from Thermobifida fusca | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated protein, Cse2 family | Authors: | Ke, A, Nam, K.H. | Deposit date: | 2012-09-20 | Release date: | 2012-10-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures. Febs Lett., 586, 2012
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4C0H
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![BU of 4c0h by Molmil](/molmil-images/mine/4c0h) | |
4LOH
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![BU of 4loh by Molmil](/molmil-images/mine/4loh) | Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4H7A
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![BU of 4h7a by Molmil](/molmil-images/mine/4h7a) | Crystal structure of CasB from Thermus thermophilus | Descriptor: | CRISPR-associated protein Cse2 | Authors: | Ke, A, Nam, K.H. | Deposit date: | 2012-09-20 | Release date: | 2012-10-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures. Febs Lett., 586, 2012
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4LOJ
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![BU of 4loj by Molmil](/molmil-images/mine/4loj) | Crystal structure of mSting in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4H45
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![BU of 4h45 by Molmil](/molmil-images/mine/4h45) | |
3PJJ
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![BU of 3pjj by Molmil](/molmil-images/mine/3pjj) | Synthetic Dimer of Human Carbonic Anhydrase II | Descriptor: | 1,1'-(oxydimethanediyl)dipyrrolidine-2,5-dione, Carbonic anhydrase 2, ZINC ION | Authors: | Snyder, P.W, Kwant, R.L, Moustakas, D.T, Mack, E.T, Butte, M.J, Whitesides, G.W. | Deposit date: | 2010-11-10 | Release date: | 2012-01-18 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | One Interface Stabilizes Linear Chains in All Polymorphs of Crystals of Human Carbonic Anhydrase II To be Published
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2LS6
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![BU of 2ls6 by Molmil](/molmil-images/mine/2ls6) | Solution NMR Structure of a Non-canonical galactose-binding CBM32 from Clostridium perfringens | Descriptor: | Hyaluronoglucosaminidase | Authors: | Grondin, J.M, Chitayat, S, Ficko-Blean, E, Boraston, A.B, Smith, S.P. | Deposit date: | 2012-04-20 | Release date: | 2013-05-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | An unusual mode of galactose recognition by a family 32 carbohydrate-binding module. J.Mol.Biol., 426, 2014
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4LOI
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![BU of 4loi by Molmil](/molmil-images/mine/4loi) | Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(2',5')p] | Descriptor: | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, PHOSPHATE ION, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOK
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![BU of 4lok by Molmil](/molmil-images/mine/4lok) | Crystal structure of mSting in complex with c[G(3',5')pA(3',5')p] | Descriptor: | 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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