PDB: 6485 resultsInfo pagesStatus searchChemie searchBIRD

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7A0Z	LppS with covalent adduct derived from 1b Descriptor: L,D-transpeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, benzenethiol Authors: Schnell, R, Steiner, E.M. Deposit date: 2020-08-11 Release date: 2021-04-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.45 Å) Cite: N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A11	LppS with covalent adduct derived from 1E Descriptor: ACETATE ION, L,D-transpeptidase 2, propane-1-thiol Authors: Schnell, R, Steiner, E.M. Deposit date: 2020-08-11 Release date: 2021-04-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.65 Å) Cite: N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A1C	LdtMT2 with covalent adduct derived from N-Thio-beta-lactam 1a Descriptor: DIMETHYL SULFOXIDE, L,D-transpeptidase 2 Authors: Schnell, R, Steiner, E.M. Deposit date: 2020-08-12 Release date: 2021-04-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.77 Å) Cite: N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
1HV9	STRUCTURE OF E. COLI GLMU: ANALYSIS OF PYROPHOSPHORYLASE AND ACETYLTRANSFERASE ACTIVE SITES Descriptor: COBALT (II) ION, COENZYME A, UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE, ... Authors: Olsen, L.R, Roderick, S.L. Deposit date: 2001-01-08 Release date: 2001-02-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the Escherichia coli GlmU pyrophosphorylase and acetyltransferase active sites. Biochemistry, 40, 2001
1HVY	Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, BETA-MERCAPTOETHANOL, THYMIDYLATE SYNTHASE, ... Authors: Phan, J, Koli, S, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L. Deposit date: 2001-01-08 Release date: 2001-01-31 Last modified: 2022-04-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug Biochemistry, 40, 2001
6ZXO	Crystal structure of His-tagged human thymidylate synthase (HT-hTS) in complex with FdUMP and Raltitrexed (Tomudex) Descriptor: 1,2-ETHANEDIOL, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, TOMUDEX, ... Authors: Pozzi, C, Mangani, S. Deposit date: 2020-07-30 Release date: 2021-05-19 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations. Cancers (Basel), 13, 2021
7CS1	Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Neomycin Descriptor: Aminoglycoside 2'-N-acetyltransferase, COENZYME A, NEOMYCIN Authors: Jeong, C.S, Hwang, J, Do, H, Lee, J.H. Deposit date: 2020-08-14 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.966 Å) Cite: Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
7CSI	Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Sisomicin Descriptor: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aminoglycoside 2'-N-acetyltransferase, COENZYME A Authors: Jeong, C.S, Hwang, J, Do, H, Lee, J.H. Deposit date: 2020-08-14 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
7DTQ	Apo Crystal Structure of Octaketide Synthase from A. arborescens Descriptor: Octaketide synthase 1 Authors: Li, T.L, Adhikari, K, Li, Y.S. Deposit date: 2021-01-06 Release date: 2022-01-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Apo Crystal Structure of Octaketide synthase from Aloe arborescens. To Be Published
7CCT	Quinolone synthase from Aegle marmelos Correa complexed with N-Methylanthraniloyl-CoA Descriptor: CADMIUM ION, N-Methylanthraniloyl-CoA, Type III polyketide synthase Authors: Mallika, V, Abhinav, K.V, Frandsen, K.E.H, Soniya, E.V. Deposit date: 2020-06-17 Release date: 2021-06-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural and mechanistic insights into Quinolone Synthase to address its functional promiscuity Commun Biol, 2024
7CSJ	Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Gentamicin Descriptor: Aminoglycoside 2'-N-acetyltransferase, COENZYME A, gentamicin C1 Authors: Jeong, C.S, Hwang, J, Do, H, Lee, J.H. Deposit date: 2020-08-14 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.168 Å) Cite: Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
4YZJ	Crystal structure of selnomethionin-labeled indole prenyltransferase TleC Descriptor: Tryptophan dimethylallyltransferase Authors: Mori, T, Matsui, T, Morita, H, Abe, I. Deposit date: 2015-03-25 Release date: 2016-03-16 Last modified: 2020-02-05 Method: X-RAY DIFFRACTION (2.106 Å) Cite: Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases. Nat Commun, 7, 2016
7CRM	Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-APO Structure Descriptor: 1,2-ETHANEDIOL, Aminoglycoside 2'-N-acetyltransferase Authors: Jeong, C.S, Hwang, J, Do, H, Lee, J.H. Deposit date: 2020-08-13 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.487 Å) Cite: Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
7CF8	PfkB(Mycobacterium marinum) Descriptor: Fructokinase, PfkB, GLYCEROL, ... Authors: Li, J, Gao, B, Ji, R. Deposit date: 2020-06-24 Release date: 2021-06-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Structural analysis and functional study of phosphofructokinase B (PfkB) from Mycobacterium marinum. Biochem.Biophys.Res.Commun., 579, 2021
7CS0	Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Paromomycin Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Aminoglycoside 2'-N-acetyltransferase, ... Authors: Jeong, C.S, Hwang, J, Do, H, Lee, J.H. Deposit date: 2020-08-14 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
1HOX	CRYSTAL STRUCTURE OF RABBIT PHOSPHOGLUCOSE ISOMERASE COMPLEXED WITH FRUCTOSE-6-PHOSPHATE Descriptor: 6-O-phosphono-beta-D-fructofuranose, PHOSPHOGLUCOSE ISOMERASE Authors: Jeffrey, C.J, Lee, J.H, Chang, K.Z, Patel, V. Deposit date: 2000-12-11 Release date: 2001-07-20 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry, 40, 2001
1HO4	CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE IN COMPLEX WITH PYRIDOXINE 5'-PHOSPHATE AND INORGANIC PHOSPHATE Descriptor: PHOSPHATE ION, PYRIDOXINE 5'-PHOSPHATE SYNTHASE, PYRIDOXINE-5'-PHOSPHATE Authors: Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. Deposit date: 2000-12-08 Release date: 2001-03-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the function of pyridoxine 5'-phosphate synthase. Structure, 9, 2001
4ZBG	Crystal Structure of a GNAT family Acetyltransferase from Brucella melitensis in complex with Acetyl-CoA Descriptor: ACETYL COENZYME *A, Acetyltransferase, GLYCEROL Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2015-04-14 Release date: 2015-04-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Crystal Structure of a GNAT family Acetyltransferase from Brucella melitensis in complex with Acetyl-CoA to be published
6UED	Apo Pseudomonas aeruginosa LpxD Structure Descriptor: GLYCEROL, MAGNESIUM ION, UDP-3-O-acylglucosamine N-acyltransferase Authors: Chen, Y, Kroeck, K, Sacco, M. Deposit date: 2019-09-20 Release date: 2019-11-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography. Sci Rep, 9, 2019
7CIX	Crystal Structure of Agmatine N-Acetyltransferase mutant S171A in complex with CoA Descriptor: Agmatine N-acetyltransferase, COENZYME A Authors: Chen, J.J, Hu, I.C, Wu, C.Y, Lyu, P.C. Deposit date: 2020-07-08 Release date: 2021-07-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.748 Å) Cite: Crystal Structure of Agmatine N-Acetyltransferase mutant S171A in complex with CoA To Be Published
7CIW	Crystal Structure of Agmatine N-Acetyltransferase mutant S171A in complex with Ac-Agm and CoA Descriptor: Agmatine N-acetyltransferase, COENZYME A, N-(4-carbamimidamidobutyl)ethanamide Authors: Chen, J.J, Hu, I.C, Wu, C.Y, Lyu, P.C. Deposit date: 2020-07-08 Release date: 2021-07-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of Agmatine N-Acetyltransferase mutant S171A in complex with Ac-Agm and CoA To Be Published
7CIU	Crystal Structure of Agmatine N-Acetyltransferase mutant S171A apo form Descriptor: Agmatine N-acetyltransferase Authors: Chen, J.J, Hu, I.C, Lai, C.H, Lyu, P.C. Deposit date: 2020-07-08 Release date: 2021-07-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.825 Å) Cite: Crystal Structure of Agmatine N-Acetyltransferase mutant S171A To Be Published
5ONC	Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch Descriptor: CHLORIDE ION, Steroid 3-ketoacyl-CoA thiolase Authors: Schaefer, C, Kuper, J, Sampson, N.S, Kisker, C. Deposit date: 2017-08-03 Release date: 2017-08-23 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch. ACS Infect Dis, 3, 2017
4ZK6	Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States Descriptor: ACETATE ION, CHLORIDE ION, IRON/SULFUR CLUSTER, ... Authors: Esakova, O.A, Grove, T.L, Saunders, A.H, Yennawar, N.H, Booker, S.J. Deposit date: 2015-04-29 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.895 Å) Cite: Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid. J.Am.Chem.Soc., 138, 2016
4ZM6	A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase Descriptor: ACETYL COENZYME *A, N-acetyl-beta-D glucosaminidase, SULFATE ION Authors: Qin, Z, Xiao, Y, Yang, X, Jiang, Z, Yang, S, Mesters, J.R. Deposit date: 2015-05-02 Release date: 2015-12-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain glycoside hydrolase family 3 beta-N-acetylglucosaminidase Sci Rep, 5, 2015

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