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3MH4
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BU of 3mh4 by Molmil
HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues
Descriptor: Protease do
Authors:Krojer, T, Sawa, J, Huber, R, Clausen, T.
Deposit date:2010-04-07
Release date:2010-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
3LNY
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BU of 3lny by Molmil
Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide
Descriptor: Rap guanine nucleotide exchange factor 6, SULFATE ION, THIOCYANATE ION, ...
Authors:Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2010-02-03
Release date:2010-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010
3LNX
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BU of 3lnx by Molmil
Second PDZ domain from human PTP1E
Descriptor: IODIDE ION, THIOCYANATE ION, Tyrosine-protein phosphatase non-receptor type 13
Authors:Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2010-02-03
Release date:2010-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.642 Å)
Cite:Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010
3KZE
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BU of 3kze by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in Complex With SSRKEYYA Peptide
Descriptor: Synthetic Peptide, T-lymphoma invasion and metastasis-inducing protein 1
Authors:Shepherd, T.R, Fuentes, E.J.
Deposit date:2009-12-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
J.Mol.Biol., 398, 2010
3KZD
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BU of 3kzd by Molmil
Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain
Descriptor: T-lymphoma invasion and metastasis-inducing protein 1
Authors:Shepherd, T.R, Fuentes, E.J.
Deposit date:2009-12-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
J.Mol.Biol., 398, 2010
3K82
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BU of 3k82 by Molmil
Crystal Structure of the third PDZ domain of PSD-95
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disks large homolog 4, GLYCEROL, ...
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2009-10-13
Release date:2010-04-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures
J.Struct.Biol., 170, 2010
3K1R
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BU of 3k1r by Molmil
Structure of harmonin NPDZ1 in complex with the SAM-PBM of Sans
Descriptor: Harmonin, Usher syndrome type-1G protein
Authors:Pan, L, Yan, J, Zhang, M.
Deposit date:2009-09-28
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins
Proc.Natl.Acad.Sci.USA, 107, 2010
3JXT
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BU of 3jxt by Molmil
Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand
Descriptor: ACETATE ION, Disks large homolog 3, Voltage-dependent calcium channel gamma-2 subunit
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-09-21
Release date:2010-09-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Caged mono- and divalent ligands for light-assisted disruption of PDZ domain-mediated interactions.
J.Am.Chem.Soc., 135, 2013
3ID4
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BU of 3id4 by Molmil
Crystal Structure of RseP PDZ2 domain fused GKASPV peptide
Descriptor: Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3ID3
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BU of 3id3 by Molmil
Crystal Structure of RseP PDZ2 I304A domain
Descriptor: Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3ID2
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BU of 3id2 by Molmil
Crystal Structure of RseP PDZ2 domain
Descriptor: IODIDE ION, Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.089 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3I4W
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BU of 3i4w by Molmil
Crystal Structure of the third PDZ domain of PSD-95
Descriptor: ACETATE ION, Disks large homolog 4
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2009-07-03
Release date:2010-04-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures
J.Struct.Biol., 170, 2010
3HVQ
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BU of 3hvq by Molmil
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Neurabin
Descriptor: GLYCEROL, MANGANESE (II) ION, Neurabin-1, ...
Authors:Critton, D.A, Ragusa, M.J, Page, R, Peti, W.
Deposit date:2009-06-16
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
3HPM
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BU of 3hpm by Molmil
Oxidized dimeric PICK1 PDZ C46G mutant in complex with the carboxyl tail peptide of GluR2
Descriptor: PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
Authors:Yu, J, Shi, Y, Zhang, M.
Deposit date:2009-06-04
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3HPK
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BU of 3hpk by Molmil
Oxidized dimeric PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
Descriptor: GLYCEROL, PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
Authors:Yu, J, Shi, Y, Zhang, M.
Deposit date:2009-06-04
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3GSL
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BU of 3gsl by Molmil
Crystal structure of PSD-95 tandem PDZ domains 1 and 2
Descriptor: Disks large homolog 4
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-03-27
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization.
Nat.Chem.Biol., 7, 2011
3GJ9
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BU of 3gj9 by Molmil
crystal structure of TIP-1 in complex with c-terminal of Kir2.3
Descriptor: C-terminal peptide from Inward rectifier potassium channel 4, CHLORIDE ION, Tax1-binding protein 3, ...
Authors:Shen, Y.
Deposit date:2009-03-08
Release date:2009-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular mechanism of inward rectifier potassium channel 2.3 regulation by tax-interacting protein-1
J.Mol.Biol., 392, 2009
3GGE
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BU of 3gge by Molmil
Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2
Descriptor: GLYCEROL, PDZ domain-containing protein GIPC2, SULFATE ION
Authors:Chaikuad, A, Hozjan, V, Yue, W, Cooper, C, Elkins, J, Pike, A.C.W, Roos, A.K, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2009-02-27
Release date:2009-03-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2
To be Published
3GDV
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BU of 3gdv by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YQF peptide
Descriptor: DegS protease, YQF peptide
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.489 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GDU
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BU of 3gdu by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YRF peptide
Descriptor: DegS protease, YRF peptide
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GDS
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BU of 3gds by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYYF peptide
Descriptor: DNRDGNVYYF peptide, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GCO
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BU of 3gco by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYQF OMP peptide
Descriptor: DNRDGNVYQF peptide, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-22
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GCN
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BU of 3gcn by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with OMP peptide (YQF)
Descriptor: Protease degS, YQF peptide
Authors:Sohn, J, Sauer, R.T, Grant, R.A.
Deposit date:2009-02-22
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Mechanisms of allosteric activation of the DegS protease by OMP-peptide binding and protein-substrate binding
To be Published
3FY5
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BU of 3fy5 by Molmil
Dishevelled PDZ domain homodimer
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Earnest, T, Friedland, N, Hung, L.-W, Moon, R.
Deposit date:2009-01-21
Release date:2009-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:

3EGH
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BU of 3egh by Molmil
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1), the PP1 binding and PDZ domains of Spinophilin and the small natural molecular toxin Nodularin-R
Descriptor: GLYCEROL, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ...
Authors:Ragusa, M.J, Page, R, Peti, W.
Deposit date:2008-09-10
Release date:2010-03-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010

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數據於2024-05-29公開中

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