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6S9I
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BU of 6s9i by Molmil
Human Brr2 Helicase Region D534C/N1866C in complex with C-tail deleted Jab1
Descriptor: Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Vester, K, Santos, K.F, Wahl, M.C.
Deposit date:2019-07-13
Release date:2020-01-22
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.
J.Biol.Chem., 295, 2020
4U34
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BU of 4u34 by Molmil
Crystal Structures of RNA Duplexes Containing 2-thio-Uridine
Descriptor: RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3')
Authors:Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W.
Deposit date:2014-07-18
Release date:2014-08-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs.
J.Am.Chem.Soc., 136, 2014
4U35
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Crystal Structures of RNA Duplexes Containing 2-thio-Uridine
Descriptor: RNA (5'-R(*GP*GP*UP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3')
Authors:Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W.
Deposit date:2014-07-18
Release date:2014-08-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs.
J.Am.Chem.Soc., 136, 2014
5OA1
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BU of 5oa1 by Molmil
RNA polymerase I pre-initiation complex
Descriptor: ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ...
Authors:Sadian, Y, Tafur, L, Kosinski, J, Jakobi, A.J, Muller, C.W.
Deposit date:2017-06-20
Release date:2017-07-26
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural insights into transcription initiation by yeast RNA polymerase I.
EMBO J., 36, 2017
7OQY
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BU of 7oqy by Molmil
Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-06-04
Release date:2021-08-25
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
7OQ4
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BU of 7oq4 by Molmil
Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-06-02
Release date:2021-08-25
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
4U47
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BU of 4u47 by Molmil
Octameric RNA duplex soaked in terbium(III)chloride
Descriptor: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), TERBIUM(III) ION
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-23
Release date:2015-08-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
5DNO
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BU of 5dno by Molmil
Crystal structure of Mmi1 YTH domain complex with RNA
Descriptor: RNA (5'-R(*CP*UP*UP*AP*AP*AP*C)-3'), YTH domain-containing protein mmi1
Authors:Wang, C.Y, Zhu, Y.W, Wu, J.H, Shi, Y.Y.
Deposit date:2015-09-10
Release date:2016-04-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1
Nucleic Acids Res., 44, 2016
4U3P
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BU of 4u3p by Molmil
Octameric RNA duplex co-crystallized with strontium(II)chloride
Descriptor: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), STRONTIUM ION
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-22
Release date:2015-07-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
1A9N
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BU of 1a9n by Molmil
CRYSTAL STRUCTURE OF THE SPLICEOSOMAL U2B''-U2A' PROTEIN COMPLEX BOUND TO A FRAGMENT OF U2 SMALL NUCLEAR RNA
Descriptor: RNA (5'-R(*CP*CP*UP*GP*GP*UP*AP*UP*UP*GP*CP*AP*GP*UP*AP*CP*CP*UP*CP*CP*AP*GP* GP*U)-3'), SPLICEOSOMAL U2B'', U2A'
Authors:Price, S.R, Evans, P.R, Nagai, K.
Deposit date:1998-04-08
Release date:1998-09-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA.
Nature, 394, 1998
3M4O
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BU of 3m4o by Molmil
RNA polymerase II elongation complex B
Descriptor: DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Zhu, G, Huang, X, Lippard, S.J.
Deposit date:2010-03-11
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M3Y
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BU of 3m3y by Molmil
RNA polymerase II elongation complex C
Descriptor: DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Zhu, G, Huang, X, Lippard, S.J.
Deposit date:2010-03-10
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
7OZN
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BU of 7ozn by Molmil
RNA Polymerase II dimer (Class 1)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Dienemann, C, Cramer, P.
Deposit date:2021-06-28
Release date:2021-10-06
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of an inactive RNA polymerase II dimer.
Nucleic Acids Res., 49, 2021
7OZP
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BU of 7ozp by Molmil
RNA Polymerase II dimer (Class 3)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Dienemann, C, Cramer, P.
Deposit date:2021-06-28
Release date:2021-10-06
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of an inactive RNA polymerase II dimer.
Nucleic Acids Res., 49, 2021
7OZO
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BU of 7ozo by Molmil
RNA Polymerase II dimer (Class 2)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Dienemann, C, Cramer, P.
Deposit date:2021-06-28
Release date:2021-10-06
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of an inactive RNA polymerase II dimer.
Nucleic Acids Res., 49, 2021
7ZWC
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BU of 7zwc by Molmil
Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter
Descriptor: Non-template strand, TATA-box-binding protein, Template strand, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-19
Release date:2022-11-30
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZXE
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BU of 7zxe by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
Descriptor: Non-template strand, TATA-box-binding protein, Template strand, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-11-30
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZAP
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BU of 7zap by Molmil
Solution structure of RBM39 RRM1 bound to U1 snRNA stem loop 3
Descriptor: RNA-binding protein 39, U1 snRNA SL3
Authors:Campagne, S, Allain, F.H.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-09-20
Method:SOLUTION NMR
Cite:Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun, 14, 2023
6SX2
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BU of 6sx2 by Molmil
dsRNA recognition by R38AK41A mutant of H7N1 NS1 RNA Binding Domain
Descriptor: 1,2-ETHANEDIOL, Non-structural protein 1, RNA (5'-R(*GP*GP*UP*AP*AP*CP*UP*GP*UP*UP*AP*CP*AP*GP*UP*UP*AP*CP*C)-3')
Authors:Coste, F, Wacquiez, A, Marc, D, Castaing, B.
Deposit date:2019-09-24
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
7OK0
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BU of 7ok0 by Molmil
Cryo-EM structure of the Sulfolobus acidocaldarius RNA polymerase at 2.88 A
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-05-17
Release date:2021-08-25
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
7KJT
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BU of 7kjt by Molmil
KEOPS tRNA modifying sub-complex of archaeal Cgi121 and tRNA
Descriptor: RNA (70-MER), Regulatory protein Cgi121
Authors:Ceccarelli, D.F, Beenstock, J, Mao, D.Y.L, Sicheri, F.
Deposit date:2020-10-26
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:A substrate binding model for the KEOPS tRNA modifying complex.
Nat Commun, 11, 2020
7LYG
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BU of 7lyg by Molmil
Zika virus RNA promoter stem-loop A with tRNA-scaffold
Descriptor: RNA promoter stem-loop A fused with tRNA
Authors:Lee, E.H, Choi, K.H.
Deposit date:2021-03-06
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.804 Å)
Cite:Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase.
Nat Commun, 12, 2021
5DCA
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BU of 5dca by Molmil
Crystal structure of yeast full length Brr2 in complex with Prp8 Jab1 domain
Descriptor: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2
Authors:Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C.
Deposit date:2015-08-23
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.
Genes Dev., 29, 2015
8B9I
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BU of 8b9i by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
1BRS
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BU of 1brs by Molmil
PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION
Descriptor: BARNASE, BARSTAR
Authors:Buckle, A.M, Schreiber, G, Fersht, A.R.
Deposit date:1994-03-11
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution.
Biochemistry, 33, 1994

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數據於2024-07-10公開中

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