4C12

X-ray Crystal Structure of Staphylococcus aureus MurE with UDP-MurNAc- Ala-Glu-Lys and ADP

Summary for 4C12

• Entry DOI: 10.2210/pdb4c12/pdb
• Related: 4C13
• Related PRD ID: PRD_002099
• Descriptor: UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--L-LYSINE LIGASE, GLYCEROL, Uridine 5'Diphospho N-acetyl muramoyl-L-Alanyl-D-Glutamyl-L-Lysine, ... (6 entities in total)
• Functional Keywords: ligase
• Biological source: STAPHYLOCOCCUS AUREUS
• Cellular location: Cytoplasm (By similarity): Q2FZP6
• Total number of polymer chains: 1
• Total formula weight: 56950.25

Authors

Fulop, V.,Roper, D.I.,Ruane, K.M.,Barreteau, H.,Boniface, A.,Dementin, S.,Blanot, D.,Mengin-Lecreulx, D.,Gobec, S.,Dessen, A.,Dowson, C.G.,Lloyd, A.J. (deposition date: 2013-08-09, release date: 2013-10-02, Last modification date: 2023-12-20)

• Primary citation: Ruane, K.M.,Lloyd, A.J.,Fulop, V.,Dowson, C.G.,Barreteau, H.,Boniface, A.,Dementin, S.,Blanot, D.,Mengin-Lecreulx, D.,Gobec, S.,Dessen, A.,Roper, D.I.; Specificity Determinants for Lysine Incorporation in Staphylococcus Aureus Peptidoglycan as Revealed by the Structure of a Mure Enzyme Ternary Complex.; J.Biol.Chem., 288:33439-, 2013; PubMed: 24064214; DOI: 10.1074/JBC.M113.508135

Experimental method

X-RAY DIFFRACTION (1.8 Å)