4C12

X-ray Crystal Structure of Staphylococcus aureus MurE with UDP-MurNAc- Ala-Glu-Lys and ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--L-LYSINE LIGASE	polymer	501	55282.5	1	UniProt (Q2FZP6) Pfam (PF08245) Pfam (PF02875) In PDB	STAPHYLOCOCCUS AUREUS	L-LYSINE-ADDING ENZYME, UDP-MURNAC-L-ALA-D-GLU\:L-LYS LIGASE, UDP-MURNAC-TRIPEPTIDE SYNTHETASE, UDP-N-ACETYLMURAMYL-TRIPEPTIDE SYNTHETASE
2	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	A	Uridine 5'Diphospho N-acetyl muramoyl-L-Alanyl-D-Glutamyl-L-Lysine	non-polymer		1007.8	1	BIRD (PRD_002099) Chemie (UML)
4	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
5	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6		water	water		18.0	490	Chemie (HOH)

Sequence modifications

A: 1 - 493 (UniProt: Q2FZP6)

PDB	External Database	Details
Arg 494	-	expression tag
Ser 495	-	expression tag
His 496	-	expression tag
His 497	-	expression tag
His 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55282.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1667.8
All*	Total formula weight	56950.2

*Water molecules are not included.