6LAX
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![BU of 6lax by Molmil](/molmil-images/mine/6lax) | the mutant SAM-VI riboswitch (U6C) bound to SAM | Descriptor: | RNA (55-MER), S-ADENOSYLMETHIONINE, U1 small nuclear ribonucleoprotein A | Authors: | Sun, A, Ren, A. | Deposit date: | 2019-11-13 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | SAM-VI riboswitch structure and signature for ligand discrimination. Nat Commun, 10, 2019
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6LAU
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![BU of 6lau by Molmil](/molmil-images/mine/6lau) | the wildtype SAM-VI riboswitch bound to SAH | Descriptor: | CESIUM ION, GUANOSINE-5'-TRIPHOSPHATE, RNA (54-MER), ... | Authors: | Ren, A, Sun, A. | Deposit date: | 2019-11-13 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.109 Å) | Cite: | SAM-VI riboswitch structure and signature for ligand discrimination. Nat Commun, 10, 2019
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6LAS
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![BU of 6las by Molmil](/molmil-images/mine/6las) | the wildtype SAM-VI riboswitch bound to SAM | Descriptor: | RNA (55-MER), S-ADENOSYLMETHIONINE, U1 small nuclear ribonucleoprotein A | Authors: | Ren, A, Sun, A. | Deposit date: | 2019-11-13 | Release date: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.708 Å) | Cite: | SAM-VI riboswitch structure and signature for ligand discrimination. Nat Commun, 10, 2019
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6KOR
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![BU of 6kor by Molmil](/molmil-images/mine/6kor) | Crystal structure of the RRM domain of SYNCRIP | Descriptor: | Heterogeneous nuclear ribonucleoprotein Q | Authors: | Chen, Y, Chan, J, Chen, W, Jobichen, C. | Deposit date: | 2019-08-12 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | SYNCRIP, a new player in pri-let-7a processing. Rna, 26, 2020
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6JVY
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![BU of 6jvy by Molmil](/molmil-images/mine/6jvy) | Crystal structure of RBM38 in complex with single-stranded DNA | Descriptor: | DNA (5'-D(*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*TP*G)-3'), RNA-binding protein 38, SULFATE ION | Authors: | Qian, K, Li, M, Wang, J, Zhang, M, Wang, M. | Deposit date: | 2019-04-17 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Structural basis for mRNA recognition by human RBM38. Biochem.J., 477, 2020
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6JVX
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![BU of 6jvx by Molmil](/molmil-images/mine/6jvx) | Crystal structure of RBM38 in complex with RNA | Descriptor: | RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3'), RNA-binding protein 38, SULFATE ION | Authors: | Qian, K, Li, M, Wang, J, Zhang, M, Wang, M. | Deposit date: | 2019-04-17 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis for mRNA recognition by human RBM38. Biochem.J., 477, 2020
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6J6Q
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![BU of 6j6q by Molmil](/molmil-images/mine/6j6q) | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6N
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![BU of 6j6n by Molmil](/molmil-images/mine/6j6n) | Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6H
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![BU of 6j6h by Molmil](/molmil-images/mine/6j6h) | Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | Descriptor: | ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6G
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![BU of 6j6g by Molmil](/molmil-images/mine/6j6g) | Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | Descriptor: | ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6ID1
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![BU of 6id1 by Molmil](/molmil-images/mine/6id1) | Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6ID0
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![BU of 6id0 by Molmil](/molmil-images/mine/6id0) | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6ICZ
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![BU of 6icz by Molmil](/molmil-images/mine/6icz) | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6HPJ
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![BU of 6hpj by Molmil](/molmil-images/mine/6hpj) | Structure of human SRSF1 RRM1 bound to AACAAA RNA | Descriptor: | Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 1, RNA (5'-R(*AP*AP*CP*AP*AP*A)-3') | Authors: | Allain, F.T.H, Clery, A. | Deposit date: | 2018-09-21 | Release date: | 2020-11-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing. Nat Commun, 12, 2021
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6HIP
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![BU of 6hip by Molmil](/molmil-images/mine/6hip) | Structure of SPF45 UHM bound to HIV-1 Rev ULM | Descriptor: | HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... | Authors: | Pabis, M, Corsini, L, Sattler, M. | Deposit date: | 2018-08-30 | Release date: | 2019-03-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47, 2019
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6GX6
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![BU of 6gx6 by Molmil](/molmil-images/mine/6gx6) | Crystal structure of IMP3 RRM12 in complex with RNA (ACAC) | Descriptor: | 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3, PHOSPHATE ION, ... | Authors: | Jia, M, Gut, H, Chao, A.J. | Deposit date: | 2018-06-26 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of IMP3 RRM12 recognition of RNA. RNA, 24, 2018
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6GSN
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![BU of 6gsn by Molmil](/molmil-images/mine/6gsn) | |
6GSM
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![BU of 6gsm by Molmil](/molmil-images/mine/6gsm) | Structure of a partial yeast 48S preinitiation complex in open conformation. | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-06-14 | Release date: | 2019-07-31 | Last modified: | 2023-02-22 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Large-scale movement of eIF3 domains during translation initiation modulate start codon selection. Nucleic Acids Res., 2021
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6GML
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![BU of 6gml by Molmil](/molmil-images/mine/6gml) | Structure of paused transcription complex Pol II-DSIF-NELF | Descriptor: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | Deposit date: | 2018-05-27 | Release date: | 2018-09-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
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6GD3
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![BU of 6gd3 by Molmil](/molmil-images/mine/6gd3) | Structure of HuR RRM3 in complex with RNA (UAUUUA) | Descriptor: | ELAV-like protein 1, RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3'), SODIUM ION | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-04-21 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6GD2
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![BU of 6gd2 by Molmil](/molmil-images/mine/6gd2) | Structure of HuR RRM3 in complex with RNA | Descriptor: | ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3') | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-04-21 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6GD1
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![BU of 6gd1 by Molmil](/molmil-images/mine/6gd1) | Structure of HuR RRM3 | Descriptor: | SODIUM ION, Thioredoxin 1,ELAV-like protein 1 | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-04-21 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6GC5
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![BU of 6gc5 by Molmil](/molmil-images/mine/6gc5) | |
6GBM
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![BU of 6gbm by Molmil](/molmil-images/mine/6gbm) | Solution structure of FUS-RRM bound to stem-loop RNA | Descriptor: | RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS | Authors: | Loughlin, F.E, Allain, F.H.-T. | Deposit date: | 2018-04-15 | Release date: | 2019-02-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. Mol. Cell, 73, 2019
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6G90
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![BU of 6g90 by Molmil](/molmil-images/mine/6g90) | Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ... | Authors: | Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K. | Deposit date: | 2018-04-10 | Release date: | 2018-08-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Prespliceosome structure provides insights into spliceosome assembly and regulation. Nature, 559, 2018
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