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4Y77
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BU of 4y77 by Molmil
Yeast 20S proteasome in complex with Ac-LAF-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAF-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-13
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
7LS2
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BU of 7ls2 by Molmil
80S ribosome from mouse bound to eEF2 (Class I)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T.
Deposit date:2021-02-17
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Nat Commun, 12, 2021
8CU8
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BU of 8cu8 by Molmil
Cryo-EM structure of Ferritin 2 from Caenorhabditis elegans, FTN-2
Descriptor: FE (III) ION, Ferritin
Authors:Malcolm, T.R, Brown, H.G, Hanssen, E.
Deposit date:2022-05-16
Release date:2023-05-24
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (1.91 Å)
Cite:Biochemical Characterization of Caenorhabditis elegans Ferritins
To Be Published
8CUJ
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BU of 8cuj by Molmil
Human excitatory amino acid transporter 3 (EAAT3) protomer in an outward facing apo state in 150 mM NMDG-Cl
Descriptor: Excitatory amino acid transporter 3
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
4Y8O
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BU of 4y8o by Molmil
Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAF-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAF-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
7X08
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BU of 7x08 by Molmil
S protein of SARS-CoV-2 in complex with 2G1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
Authors:Guo, Y.Y, Zhang, Y.Y, Zhou, Q.
Deposit date:2022-02-21
Release date:2022-03-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
Cell Discov, 8, 2022
4Y6Z
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BU of 4y6z by Molmil
Yeast 20S proteasome in complex with Ac-PAL-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAL-ep, CHLORIDE ION, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2015-02-13
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8H
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BU of 4y8h by Molmil
Yeast 20S proteasome in complex with N3-APAL-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4YA2
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BU of 4ya2 by Molmil
Yeast 20S proteasome beta2-H116N mutant in complex with Ac-LAE-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAE-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-17
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8T
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BU of 4y8t by Molmil
Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAE-ep
Descriptor: Ac-PAE-ep, MAGNESIUM ION, Proteasome subunit alpha type-1, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
7WUH
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BU of 7wuh by Molmil
SARS-CoV-2 Spike in complex with Fab of m31A7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, X, Wu, Y.-M.
Deposit date:2022-02-08
Release date:2022-03-23
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models.
Sci Transl Med, 14, 2022
8D56
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BU of 8d56 by Molmil
One RBD-up state of SARS-CoV-2 BA.2 variant spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J, Tang, W.C, Gao, H.L, Shi, W, Peng, H.Q, Volloch, S.R, Xiao, T.S, Chen, B.
Deposit date:2022-06-04
Release date:2023-06-07
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and functional characteristics of the SARS-CoV-2 Omicron subvariant BA.2 spike protein.
Nat.Struct.Mol.Biol., 30, 2023
7LU5
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BU of 7lu5 by Molmil
SAMHD1(113-626) H206R D207N R366H
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Authors:Temple, J.T, Bowen, N.E.
Deposit date:2021-02-20
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
J.Biol.Chem., 297, 2021
8D55
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BU of 8d55 by Molmil
Closed state of SARS-CoV-2 BA.2 variant spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, J, Tang, W.C, Gao, H.L, Shi, W, Peng, H.Q, Volloch, S.R, Xiao, T.S, Chen, B.
Deposit date:2022-06-04
Release date:2023-06-07
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural and functional characteristics of the SARS-CoV-2 Omicron subvariant BA.2 spike protein.
Nat.Struct.Mol.Biol., 30, 2023
8CUI
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BU of 8cui by Molmil
Human excitatory amino acid transporter 3 (EAAT3) in an intermediate outward facing apo state
Descriptor: Excitatory amino acid transporter 3
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
7LI9
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BU of 7li9 by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI8
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BU of 7li8 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in inward open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, DODECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LKY
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BU of 7lky by Molmil
Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641
Descriptor: DIMETHYL SULFOXIDE, Isoform 1 of PHD finger protein 1, Peptidomimetic inhibitor UNC6641, ...
Authors:Liu, J, Kutateladze, T.G.
Deposit date:2021-02-03
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1).
J.Med.Chem., 64, 2021
5WJZ
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BU of 5wjz by Molmil
Cryo-EM structure of B. subtilis flagellar filaments E115G
Descriptor: Flagellin
Authors:Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H.
Deposit date:2017-07-24
Release date:2017-10-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:A structural model of flagellar filament switching across multiple bacterial species.
Nat Commun, 8, 2017
7LI7
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BU of 7li7 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in occluded conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
8CUA
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BU of 8cua by Molmil
Human excitatory amino acid transporter 3 (EAAT3) with bound potassium in an intermediate outward facing state
Descriptor: Excitatory amino acid transporter 3, MERCURY (II) ION, POTASSIUM ION
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
7L9E
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BU of 7l9e by Molmil
Crystal structure of apo-alpha glucosidase
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-01-03
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity.
J.Med.Chem., 64, 2021
7LI6
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BU of 7li6 by Molmil
apo SERT reconstituted in lipid nanodisc in KCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
5WSG
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BU of 5wsg by Molmil
Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution
Descriptor: 3'-exon-intron, 3'-intron-lariat, 5'-exon, ...
Authors:Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
Deposit date:2016-12-07
Release date:2017-01-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a yeast step II catalytically activated spliceosome
Science, 355, 2017
7L6B
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BU of 7l6b by Molmil
The empty AAV12 capsid
Descriptor: VP1
Authors:Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2020-12-23
Release date:2021-02-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Completion of the AAV Structural Atlas: Serotype Capsid Structures Reveals Clade-Specific Features.
Viruses, 13, 2021

225681

數據於2024-10-02公開中

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