7WUH

SARS-CoV-2 Spike in complex with Fab of m31A7

Summary for 7WUH

• Entry DOI: 10.2210/pdb7wuh/pdb
• EMDB information: 32832
• Descriptor: Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• Functional Keywords: sars-cov-2, monoclonal antibody, broad neutralization, m31a7, mono-glcnac-decorated s vaccine, memory b cells, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 9
• Total formula weight: 588377.94

Authors

Chen, X.,Wu, Y.-M. (deposition date: 2022-02-08, release date: 2022-03-23, Last modification date: 2022-07-06)

• Primary citation: Huang, H.Y.,Liao, H.Y.,Chen, X.,Wang, S.W.,Cheng, C.W.,Shahed-Al-Mahmud, M.,Liu, Y.M.,Mohapatra, A.,Chen, T.H.,Lo, J.M.,Wu, Y.M.,Ma, H.H.,Chang, Y.H.,Tsai, H.Y.,Chou, Y.C.,Hsueh, Y.P.,Tsai, C.Y.,Huang, P.Y.,Chang, S.Y.,Chao, T.L.,Kao, H.C.,Tsai, Y.M.,Chen, Y.H.,Wu, C.Y.,Jan, J.T.,Cheng, T.R.,Lin, K.I.,Ma, C.,Wong, C.H.; Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models.; Sci Transl Med, 14:eabm0899-eabm0899, 2022; PubMed: 35230146; DOI: 10.1126/scitranslmed.abm0899

Experimental method

ELECTRON MICROSCOPY (4.7 Å)