5C9K
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3BIA
| Tim-4 in complex with sodium potassium tartrate | Descriptor: | L(+)-TARTARIC ACID, SODIUM ION, T-cell immunoglobulin and mucin domain-containing protein 4 | Authors: | Santiago, C, Ballesteros, A, Kaplan, G.G, Freeman, G.J, Casasnovas, J.M. | Deposit date: | 2007-11-30 | Release date: | 2008-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds. Immunity, 27, 2007
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5C2B
| anti-CXCL13 parental scFv - 3B4 | Descriptor: | CHLORIDE ION, scFv 3B4 | Authors: | Tu, C, Bard, J, Mosyak, L. | Deposit date: | 2015-06-15 | Release date: | 2015-11-04 | Last modified: | 2020-06-17 | Method: | X-RAY DIFFRACTION (1.4049 Å) | Cite: | Optimization of a scFv-based biotherapeutic by CDR side-chain clash repair To Be Published
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5C6W
| anti-CXCL13 scFv - E10 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Tu, C, Bard, J, Mosyak, L. | Deposit date: | 2015-06-23 | Release date: | 2015-11-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Optimization of a scFv-based biotherapeutic by CDR side-chain clash repair To Be Published
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5DZL
| Crystal structure of the protein human CEACAM1 | Descriptor: | Carcinoembryonic antigen-related cell adhesion molecule 1 | Authors: | Huang, Y.H, Russell, A, Gandhi, A.K, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | Deposit date: | 2015-09-25 | Release date: | 2015-10-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.4006 Å) | Cite: | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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5E56
| Crystal structure of mouse CTLA-4 | Descriptor: | Cytotoxic T-lymphocyte protein 4, SODIUM ION | Authors: | Fedorov, A.A, Fedorov, E.V, SAMANTA, D, Bonanno, J.B, Almo, S.C. | Deposit date: | 2015-10-07 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.504 Å) | Cite: | Crystal structure of mouse CTLA-4 To Be Published
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5EB9
| Crystal Structure Of Chicken CD8aa Homodimer | Descriptor: | CD8 alpha chain | Authors: | Liu, Y.J, Qi, J.X, Xia, C. | Deposit date: | 2015-10-18 | Release date: | 2016-09-14 | Method: | X-RAY DIFFRACTION (2.006 Å) | Cite: | The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species. Sci Rep, 6, 2016
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2ZG3
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3BDX
| Crystal structure of the unstable and highly fibrillogenic Pro7Ser mutant of the Recombinant variable domain 6AJL2 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Amyloid lambda 6 light chain variable region PIP (fragment), ... | Authors: | Hernandez-Santoyo, A, Fuentes-Silva, D, Del Pozo Yauner, L, Becerril, B, Rodriguez-Romero, A. | Deposit date: | 2007-11-15 | Release date: | 2008-10-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A single mutation at the sheet switch region results in conformational changes favoring lambda6 light-chain fibrillogenesis. J.Mol.Biol., 396, 2010
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3B9K
| Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab Light Chain, ... | Authors: | Shore, D, Wilson, I.A. | Deposit date: | 2007-11-05 | Release date: | 2008-11-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 alphabeta to MHC Class I J.Mol.Biol., 384, 2008
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3BDB
| Crystal Structure of Novel Immune-Type Receptor 11 Extracellular Fragment from Ictalurus punctatus including Stalk Region | Descriptor: | Novel immune-type receptor 11 | Authors: | Ostrov, D.A, Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Magis, A.T, Bailey, K.M, Litman, G.W. | Deposit date: | 2007-11-14 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition. Immunity, 29, 2008
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3B5T
| Crystal Structure of Novel Immune-Type Receptor 10 Se-Met Extracellular Fragment Mutant N30D | Descriptor: | Novel immune-type receptor 10 | Authors: | Ostrov, D.A, Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Magis, A.T, Bailey, K.M, Litman, G.W. | Deposit date: | 2007-10-26 | Release date: | 2008-06-24 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition. Immunity, 29, 2008
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3BJ9
| Crystal structure of the Surrogate Light Chain Variable Domain VpreBJ | Descriptor: | 1,2-ETHANEDIOL, Immunoglobulin iota chain, Immunoglobulin lambda-like polypeptide 1 | Authors: | Morstadt, L.M, Bohm, A.A, Stollar, B.D, Baleja, J.D. | Deposit date: | 2007-12-03 | Release date: | 2008-03-04 | Last modified: | 2019-09-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Engineering and characterization of a single chain surrogate light chain variable domain. Protein Sci., 17, 2008
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3BI9
| Tim-4 | Descriptor: | ACETATE ION, T-cell immunoglobulin and mucin domain-containing protein 4 | Authors: | Santiago, C, Ballesteros, A, Kaplan, G.G, Freeman, G.J, Casasnovas, J.M. | Deposit date: | 2007-11-30 | Release date: | 2008-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds. Immunity, 27, 2007
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3BIB
| Tim-4 in complex with phosphatidylserine | Descriptor: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, SODIUM ION, T-cell immunoglobulin and mucin domain-containing protein 4 | Authors: | Santiago, C, Ballesteros, A, Kaplan, G.G, Freeman, G.J, Casasnovas, J.M. | Deposit date: | 2007-11-30 | Release date: | 2008-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds. Immunity, 27, 2007
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3BX7
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1DLF
| HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FV FRAGMENT FROM AN ANTI-DANSYL SWITCH VARIANT ANTIBODY IGG2A(S) CRYSTALLIZED AT PH 5.25 | Descriptor: | ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S), SULFATE ION | Authors: | Nakasako, M, Takahashi, H, Shimada, I, Arata, Y. | Deposit date: | 1998-07-14 | Release date: | 1999-07-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody. J.Mol.Biol., 291, 1999
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1EK3
| KAPPA-4 IMMUNOGLOBULIN VL, REC | Descriptor: | CALCIUM ION, CHLORIDE ION, KAPPA-4 IMMUNOGLOBULIN LIGHT CHAIN VL | Authors: | Pokkuluri, P.R, Huang, D.-B, Raffen, R, Stevens, F.J, Schiffer, M. | Deposit date: | 2000-03-06 | Release date: | 2001-03-06 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Structure of Amyloidogenic Kappa-4 Immunoglobulin VL, REC To be Published
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1EEU
| M4L/Y(27D)D/Q89D/T94H mutant of LEN | Descriptor: | ISOPROPYL ALCOHOL, KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | Deposit date: | 2000-02-03 | Release date: | 2001-02-03 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions. Protein Sci., 11, 2002
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1EFQ
| Q38D mutant of LEN | Descriptor: | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), URANYL (VI) ION, ZINC ION | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | Deposit date: | 2000-02-09 | Release date: | 2001-02-09 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions. Protein Sci., 11, 2002
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1EEQ
| M4L/Y(27D)D/T94H Mutant of LEN | Descriptor: | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | Authors: | Pokkuluri, P.R, Raffen, R, Dieckman, L, Boogaard, C, Stevens, F.J, Schiffer, M. | Deposit date: | 2000-02-01 | Release date: | 2001-02-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Increasing protein stability by polar surface residues: domain-wide consequences of interactions within a loop. Biophys.J., 82, 2002
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1EAJ
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1DCL
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1CFV
| MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI | Descriptor: | ESTRONE BETA-D-GLUCURONIDE, MONOCLONAL ANTIBODY FV4155, ZINC ION | Authors: | Trinh, C.H, Phillips, S.E.V. | Deposit date: | 1997-04-11 | Release date: | 1997-10-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity. Structure, 5, 1997
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1DL7
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