3DAH
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7P9N
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![BU of 7p9n by Molmil](/molmil-images/mine/7p9n) | Crystal structure of CD73 in complex with AMP in the open form | Descriptor: | 5'-nucleotidase, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-27 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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6SHQ
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![BU of 6shq by Molmil](/molmil-images/mine/6shq) | Escherichia coli AGPase in complex with AMP. Symmetry C2 | Descriptor: | ADENOSINE MONOPHOSPHATE, Glucose-1-phosphate adenylyltransferase | Authors: | Cifuente, J.O, Comino, N, D'Angelo, C, Marina, A, Gil-Carton, D, Albesa-Jove, D, Guerin, M.E. | Deposit date: | 2019-08-07 | Release date: | 2020-02-05 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM. Curr Res Struct Biol, 2, 2020
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6SI8
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![BU of 6si8 by Molmil](/molmil-images/mine/6si8) | Escherichia coli AGPase in complex with AMP. | Descriptor: | ADENOSINE MONOPHOSPHATE, Glucose-1-phosphate adenylyltransferase | Authors: | Cifuente, J.O, Comino, N, D'Angelo, C, Marina, A, Gil-Carton, D, Albesa-Jove, D, Guerin, M.E. | Deposit date: | 2019-08-09 | Release date: | 2020-02-05 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM. Curr Res Struct Biol, 2, 2020
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2ERZ
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![BU of 2erz by Molmil](/molmil-images/mine/2erz) | Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil | Descriptor: | 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, cAMP-dependent protein kinase inhibitor, alpha form, ... | Authors: | Jacobs, M. | Deposit date: | 2005-10-25 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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6F2V
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![BU of 6f2v by Molmil](/molmil-images/mine/6f2v) | Crystal structure of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3) in complex with AMP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... | Authors: | Dohler, C, Zebisch, M, Strater, N. | Deposit date: | 2017-11-27 | Release date: | 2018-08-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure and substrate binding mode of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3). Sci Rep, 8, 2018
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4TS5
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![BU of 4ts5 by Molmil](/molmil-images/mine/4ts5) | Sulfolobus solfataricus adenine phosphoribosyltransferase with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Purine phosphoribosyltransferase (GpT-1) | Authors: | Kadziola, A. | Deposit date: | 2014-06-18 | Release date: | 2014-07-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Adenine Phosphoribosyltransferase from Sulfolobus solfataricus Is an Enzyme with Unusual Kinetic Properties and a Crystal Structure that Suggests It Evolved from a 6-Oxopurine Phosphoribosyltransferase. Biochemistry, 54, 2015
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1DEL
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2VFY
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6FCL
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6FD6
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![BU of 6fd6 by Molmil](/molmil-images/mine/6fd6) | Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 30 days post crystallization (with AMP and PPi products fully generated) | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, MAGNESIUM ION, ... | Authors: | Nioche, P, Huyet, J, Ozeir, M. | Deposit date: | 2017-12-21 | Release date: | 2018-08-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase. Cell Chem Biol, 25, 2018
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4J75
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![BU of 4j75 by Molmil](/molmil-images/mine/4j75) | Crystal Structure of a parasite tRNA synthetase, product-bound | Descriptor: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | Authors: | Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J. | Deposit date: | 2013-02-12 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design. Mol.Biochem.Parasitol., 189, 2013
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2F17
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![BU of 2f17 by Molmil](/molmil-images/mine/2f17) | Mouse Thiamin Pyrophosphokinase in a Ternary Complex with Pyrithiamin Pyrophosphate and AMP at 2.5 angstrom | Descriptor: | 1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-METHYLPYRIDINIUM, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, ... | Authors: | Liu, J.Y, Timm, D.E, Hurley, T.D. | Deposit date: | 2005-11-14 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Pyrithiamine as a substrate for thiamine pyrophosphokinase J.Biol.Chem., 281, 2006
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4OZL
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![BU of 4ozl by Molmil](/molmil-images/mine/4ozl) | GlnK2 from Haloferax mediterranei complexed with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Nitrogen regulatory protein P-II, SULFATE ION | Authors: | Palanca, C, Pedro-Roig, L, Llacer, J.L, Camacho, M, Bonete, M.J, Rubio, V. | Deposit date: | 2014-02-17 | Release date: | 2014-07-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4942 Å) | Cite: | The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations. Febs J., 281, 2014
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3SZQ
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![BU of 3szq by Molmil](/molmil-images/mine/3szq) | Structure of an S. pombe APTX/DNA/AMP/Zn complex | Descriptor: | 5'-D(*CP*CP*CP*TP*G)-3', 5'-D(*TP*AP*TP*CP*GP*GP*AP*AP*TP*CP*AP*GP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ... | Authors: | Tumbale, P, Krahn, J, Williams, R.S. | Deposit date: | 2011-07-19 | Release date: | 2011-10-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.353 Å) | Cite: | Structure of an aprataxin-DNA complex with insights into AOA1 neurodegenerative disease. Nat.Struct.Mol.Biol., 18, 2011
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1KHZ
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![BU of 1khz by Molmil](/molmil-images/mine/1khz) | Structure of the ADPR-ase in complex with AMPCPR and Mg | Descriptor: | ADP-ribose pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, CHLORIDE ION, ... | Authors: | Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M. | Deposit date: | 2001-12-01 | Release date: | 2002-10-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase. Biochemistry, 41, 2002
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5UJJ
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3E3N
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![BU of 3e3n by Molmil](/molmil-images/mine/3e3n) | The Glycogen phosphorylase b R state- AMP complex | Descriptor: | ADENOSINE MONOPHOSPHATE, Glycogen phosphorylase, muscle form, ... | Authors: | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2008-08-07 | Release date: | 2009-08-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Glycogen phosphorylase revisited: extending the resolution of the R- and T-state structures of the free enzyme and in complex with allosteric activators. Acta Crystallogr.,Sect.F, 77, 2021
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5X0F
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5X0J
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![BU of 5x0j by Molmil](/molmil-images/mine/5x0j) | Free serine kinase (E30Q mutant) in complex with phosphoserine and AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Free serine kinase, MAGNESIUM ION, ... | Authors: | Nagata, R, Fujihashi, M, Miki, K. | Deposit date: | 2017-01-20 | Release date: | 2017-04-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structural Study on the Reaction Mechanism of a Free Serine Kinase Involved in Cysteine Biosynthesis ACS Chem. Biol., 12, 2017
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6ZZ9
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5DJI
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![BU of 5dji by Molmil](/molmil-images/mine/5dji) | Structure of M. tuberculosis CysQ, a PAP phosphatase with AMP, PO4, and 2Mg bound | Descriptor: | 3'-phosphoadenosine 5'-phosphate phosphatase, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Fisher, A.J, Erickson, A.I. | Deposit date: | 2015-09-02 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.659 Å) | Cite: | Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound. Biochemistry, 54, 2015
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5DJH
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![BU of 5djh by Molmil](/molmil-images/mine/5djh) | Structure of M. tuberculosis CysQ, a PAP phosphatase with AMP, PO4, and 3Mg bound | Descriptor: | 3'-phosphoadenosine 5'-phosphate phosphatase, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Fisher, A.J, Erickson, A.I. | Deposit date: | 2015-09-02 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound. Biochemistry, 54, 2015
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5L6V
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![BU of 5l6v by Molmil](/molmil-images/mine/5l6v) | Crystal structure of E. coli ADP-glucose pyrophosphorylase (AGPase) in complex with a negative allosteric regulator adenosine monophosphate (AMP) - AGPase*AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Glucose-1-phosphate adenylyltransferase, PHOSPHATE ION, ... | Authors: | Cifuente, J.O, Albesa-Jove, D, Comino, N, Madariaga-Marcos, J, Agirre, J, Lopez-Fernandez, S, Garcia-Alija, M, Guerin, M.E. | Deposit date: | 2016-05-31 | Release date: | 2016-09-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.667 Å) | Cite: | Structural Basis of Glycogen Biosynthesis Regulation in Bacteria. Structure, 24, 2016
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1MDB
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![BU of 1mdb by Molmil](/molmil-images/mine/1mdb) | CRYSTAL STRUCTURE OF DhbE IN COMPLEX WITH DHB-ADENYLATE | Descriptor: | 2,3-DIHYDROXY-BENZOIC ACID, 2,3-dihydroxybenzoate-AMP ligase, ADENOSINE MONOPHOSPHATE, ... | Authors: | May, J.J, Kessler, N, Marahiel, M.A, Stubbs, M.T. | Deposit date: | 2002-08-07 | Release date: | 2002-09-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases. Proc.Natl.Acad.Sci.USA, 99, 2002
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